Cullgen

San Diego, United States Founded: 2018 • Age: 8 yrs Acquired By Gyre Therapeutics
Developer of small molecules targeting the ubiquitin-proteasome system

About Cullgen

Cullgen is a company based in San Diego (United States) founded in 2018 by Yue Xiong and Jian Jin was acquired by Gyre Therapeutics in March 2026.. Cullgen has raised $121 million across 4 funding rounds from investors including Gyre Therapeutics, GNI Group and Sincere Capital.

  • Headquarter San Diego, United States
  • Founders Yue Xiong, Jian Jin
  • Sectors
    Healthcare
  • Email
    ***********
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Cullgen Inc
Operational Areas
Healthcare → Pharmaceuticals & Therapeutics
Key Metrics
  • Annual Revenue
  • Net Profit
  • EBITDA
  • Total Equity Funding
    $121 M (USD)

    in 4 rounds

  • Latest Funding Round
    $40 M (USD), Series B

    May 08, 2023

  • Investors
  • Employee Count
    Employee Count
  • Acquired by
    Gyre Therapeutics

    (Mar 02, 2026)

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People of Cullgen
Headcount 50-200
Employee Profiles 11
Board Members and Advisors 10
Employee Profiles
People
Ying Luo
Chairman & President
People
Jialiang Wang
SVP, Translational Medicine
People
Yue Xiong
Chief Scientific Officer
People
Thomas Eastling
CFO

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Board Members and Advisors
people
Rodney L. Nussbaum
Director
people
Timothy Heffernan
Scientific Advisor
people
Trency Gu
Director
people
Frank Yan
Director

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Funding Insights of Cullgen

Cullgen has successfully raised a total of $121M across 4 strategic funding rounds. The most recent funding activity was a Series B round of $40 million completed in May 2023. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 4
  • Last Round Series B — $40.0M
  • First Round

    (02 Mar 2018)

  • Investors Count 12
Date Amount Transaction Name Valuation Lead Investors Investors
May, 2023 Amount Series B - Cullgen Valuation CICC Capital
Feb, 2021 Amount Series B - Cullgen Valuation 3E BioVentures
Apr, 2019 Amount Series A - Cullgen Valuation Highlight Capital , Sequoia Capital
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Investors in Cullgen

Cullgen has secured backing from 13 investors, including venture fund and institutional investors. Prominent investors backing the company include Gyre Therapeutics, GNI Group and Sincere Capital. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Investor Description Founded Year Domain Location
-
Founded Year Domain Location
Early-stage US tech investments are managed by Voyager Capital.
Founded Year Domain Location
Venture capital investments are made in technology and biotech sectors.
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by Cullgen

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016

Financial Statements - Cullgen

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Cullgen Comparisons

Employees
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Competitors of Cullgen

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

Latest news on Cullgen

Frequently Asked Questions about Cullgen

When was Cullgen founded?

Cullgen was founded in 2018.

Where is Cullgen located?

Cullgen is headquartered in San Diego, United States. It is registered at San Diego, California, United States.

Who is the current CEO of Cullgen?

Ying Luo is the current CEO of Cullgen.

Is Cullgen a funded company?

Cullgen is a funded company, having raised a total of $121M across 4 funding rounds to date. The company's 1st funding round was a Series A of $16M, raised on Mar 02, 2018.

What does Cullgen do?

Cullgen is developing small molecules for the treatment of cancer, inflammatory, and autoimmune diseases. The company has developed uSMITE, a protein degradation technology. The company is developing drugs using its technology which is based on ubiquitin-mediated small molecule induced target elimination. The candidate is targeting the ubiquitin-proteasome system. It is in the preclinical stage as of Feb 2019.

Who are Cullgen's investors?

Cullgen has 13 investors. Key investors include Gyre Therapeutics, GNI Group, Sincere Capital, Voyager Capital, and Wuxi Venture Capital Group.

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