Entasis Therapeutics

Waltham, United States Founded: 2015 • Age: 11 yrs Listed Acquired By Innoviva
Small molecules for drug-resistant bacterial infections are developed.

About Entasis Therapeutics

Entasis Therapeutics is a Healthcare company based in Waltham (United States) founded in 2015, and was acquired by Innoviva in May 2022. Small molecules for drug-resistant bacterial infections are developed. Entasis Therapeutics has raised $121.9 million across 5 funding rounds from investors including Astrazeneca, Blackstone and TPG. The company has 40 employees. The company was acqui-hired. Entasis Therapeutics offers products and services including GIAPREZA, XERAVA, XACDURO, and ZOLIFLODACIN. Its focus areas include Life Sciences, Infectious Diseases, Drugs and Bacterial. Its legal entity is Innoviva Specialty Therapeutics. Its competitors include Paratek Pharma, Spero Therapeutics and Cempra; 3 of its 3 listed competitors have raised funding.

Company details

Entasis Therapeutics was founded in 2015 and is based in Waltham, United States, within the biotechnology sector. Focus is placed on developing small-molecule antibiotics targeting multidrug-resistant Gram-negative infections, such as those caused by Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae. A single-dose oral therapy for both susceptible and resistant Neisseria gonorrhoeae is also pursued. The lead candidate, ETX0914, is advanced as an oral antibiotic for uncomplicated gonorrhea treatment.

  • Headquarters Waltham, United States
  • Employees 40
  • Stage Public
  • Sectors
    Healthcare
  • Website entasistx.com
  • Social LinkedIn X
  • Acquired by Innoviva (May 2022)
  • Legal Name Innoviva Specialty Therapeutics
Operational Areas
Key Metrics
  • Annual Revenue
    $7 M (USD)
    40
    as on Dec 31, 2019
  • Total Equity Funding
    $121.9M (USD)

    in 5 rounds

  • Latest Funding Round
    $25M (USD), Post-IPO

    Aug 2020

  • Investors
  • Employee Count
    40
  • Acquired by
    Innoviva

    (May 2022)

Products & Services of Entasis Therapeutics

Entasis Therapeutics offers a comprehensive portfolio of products and services, including GIAPREZA, XERAVA, XACDURO, and ZOLIFLODACIN.

GIAPREZA
Therapy

Treats critical care conditions like low blood pressure.

XERAVA
Antibiotic

Fights serious bacterial infections in hospitalized patients.

XACDURO
Antibiotic

Addresses infections caused by drug-resistant microorganisms.

ZOLIFLODACIN
Investigational Antibiotic

Targets uncomplicated gonorrhea infections in clinical development.

Funding Insights of Entasis Therapeutics

Entasis Therapeutics has successfully raised a total of $121.9M across 5 strategic funding rounds. The most recent funding activity was a Post-IPO round of $25 million completed in August 2020. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $121.9M
  • Total Rounds 5
  • Last Round Post-IPO β€” $25M
  • First Round $40M

    (Mar 2015)

  • Investors Count 9

All 5 funding rounds of Entasis Therapeutics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Aug 2020$25MPost-IPO––
Apr 2020$35MPost-IPO––
Sep 2017$31.9MSeries B––
Apr 2016$50MSeries B––
Mar 2015$40MSeries A––
Valuation history

9 investors in total: 9 institutional.

Investors in Entasis Therapeutics

Entasis Therapeutics has secured backing from 9 investors, including institutional and venture fund investors. Prominent investors backing the company include Astrazeneca, Blackstone and TPG.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Biotech funding, drug development support, and investment in life sciences.
sofinnova.com
Fund of funds focused on pre-seed and seed-stage companies
1992tpg.comFort Worth, United States
Healthcare sector private equity investments are managed by the firm.
1991frazierhealthcare.comSeattle, United States
Diversified investment management is provided across multiple asset classes.
1985blackstone.comNew York, United States
Private equity and venture capital fund focused on the healthcare sector
novoholdings.dkHellerup, Denmark
Respiratory prescription drugs are developed and in-licensed for COPD treatment.
1996inva.comBrisbane, United States
A global healthcare investment firm supporting therapeutic-focused companies.
2017pivotalbiovp.comSan Francisco, United States
Eventide Mutual Funds is managed by Eventide Asset Management, offering investment solutions.
eventidefunds.comBoston, United States
Pharmaceutical and biologics products are developed and distributed worldwide.
1913astrazeneca.comCambridge, United Kingdom
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Investor details for Entasis Therapeutics

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People of Entasis Therapeutics

8 people are tracked at Entasis Therapeutics (7 in board & advisors, 1 in team); the tracked headcount is 40.

NameRoleGroup
Paul G Ambrose
Clinical Board MemberBoard & advisors
Mark Noe
Clinical Board MemberBoard & advisors
Karen Bush
Clinical Board MemberBoard & advisors
Louis B. Rice
Clinical Board MemberBoard & advisors
Andrew F. Shorr
Clinical Board MemberBoard & advisors
Helen W. Boucher
Clinical Board MemberBoard & advisors
Kerry Laplante
Clinical Board MemberBoard & advisors
Betzy Keiley
General CounselTeam
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Complete people profiles for Entasis Therapeutics

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Timeline of Entasis Therapeutics

5 dated milestones of Entasis Therapeutics across 7 years, from founding to its latest funding, stage changes and deals.

  1. Founded Entasis Therapeutics is founded.
  2. Funding First funding round of $40.0M.
  3. IPO Lists on the stock exchange (IPO).
  4. Funding Latest funding round, Post-IPO, of $25.0M.
  5. Exit Acquired by Innoviva.

Competitors of Entasis Therapeutics

Entasis Therapeutics has 3 listed competitors in our database, 3 of them funded. They include Paratek Pharma, Spero Therapeutics and Cempra.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
paratekpharma.com1996Boston, United States$96.48M205
Therapeutics for antimicrobial resistant infections are developed.
sperotherapeutics.com2013Cambridge, United States$114.7M46
Therapeutics for drug-resistant bacterial infections are developed.
cempra.com2006Chapel Hill, United States$149.5M78
Clinical-stage pharmaceutical company focused on developing antibacterials
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Detailed competitors of Entasis Therapeutics

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Top companies in Infectious Diseases

3 companies that operate in the same segment as Entasis Therapeutics (Infectious Diseases) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Developer of molecular diagnostic testing solutions
1996Sunnyvale, California, United StatesUSD 19.1 MUSD 54.88 M208
Therapeutics for drug-resistant bacterial infections are developed.
2013Cambridge, Massachusetts, United StatesUSD 114.7 MUSD 59.62 M32
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Related news about Entasis Therapeutics

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Frequently Asked Questions about Entasis Therapeutics

Entasis Therapeutics was founded in 2015.

Entasis Therapeutics is headquartered in Waltham, United States. It is registered at Waltham, Massachusetts, United States.

Entasis Therapeutics is a funded company, having raised a total of $121.9M across 5 funding rounds to date. The company's 1st funding round was a Series A of $40M, raised on Mar 2015.

Entasis Therapeutics has 40 employees.

Annual revenue of Entasis Therapeutics is $7M as on Dec 31, 2019.

Entasis Therapeutics was founded in 2015 and is based in Waltham, United States, within the biotechnology sector. Focus is placed on developing small-molecule antibiotics targeting multidrug-resistant Gram-negative infections, such as those caused by Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae. A single-dose oral therapy for both susceptible and resistant Neisseria gonorrhoeae is also pursued. The lead candidate, ETX0914, is advanced as an oral antibiotic for uncomplicated gonorrhea treatment.

Entasis Therapeutics's top competitors include Spero Therapeutics, Paratek Pharma and Cempra.

Entasis Therapeutics offers GIAPREZA, XERAVA, XACDURO, and ZOLIFLODACIN.

Entasis Therapeutics has 9 investors. Key investors include Astrazeneca, Blackstone, TPG, Innoviva, and Frazier Healthcare Partners.

Entasis Therapeutics operates through Innoviva Specialty Therapeutics.

Yes. Entasis Therapeutics was acquired by Innoviva in May 2022.

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