HistoSonics

Ann Arbor, United States Founded: 2009 • Age: 17 yrs Acquired By K5 Global
Tissue ablation is achieved through non-invasive ultrasound Histotripsy technology.
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About HistoSonics

HistoSonics is a company based in Ann Arbor (United States) founded in 2009 was acquired by K5 Global in August 2025.. HistoSonics has raised $565.73 million across 11 funding rounds from investors including Varian, University of Michigan and Fletcher Spaght. The company has 56 employees as of December 31, 2022. HistoSonics offers products and services including Histotripsy System and Clinical Trials Platform. HistoSonics operates in a competitive market with competitors including Insightec, Profound Medical, Theraclion, Carthera and SONIRE Therapeutics, among others.

  • Headquarter Ann Arbor, United States
  • Employees 56 as on 31 Dec, 2022
  • Sectors
    Healthcare
  • Email
    ***********
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Histosonics, Inc Attn Christine
Operational Areas
Healthcare → Healthcare Products & Supplies
Key Metrics
  • Annual Revenue
  • Net Profit
  • EBITDA
  • Total Equity Funding
    $565.73 M (USD)

    in 11 rounds

  • Latest Funding Round
    $250 M (USD), Series E

    Oct 16, 2025

  • Investors
    Varian

    & 23 more

  • Employee Count
    56

    as on Dec 31, 2022

  • Acquired by
    K5 Global

    (Aug 07, 2025)

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Products & Services of HistoSonics

HistoSonics offers a comprehensive portfolio of products and services, including Histotripsy System and Clinical Trials Platform. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.

Primary

Non-invasive platform for mechanical destruction of liver tumors.

System for testing histotripsy in oncology applications.

People of HistoSonics
Headcount 10-50
Employee Profiles 92
Board Members and Advisors 7
Employee Profiles
People
Ariful Sunny
Software Test Engineer
People
David Krenn
Chief Financial Officer
People
Joseph Herman
Medical Director
People
Jeff Bruno
Account Manager

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Board Members and Advisors
people
Fred Lee Jr.
Board Member
people
Wen Chen
Board Member
people
Gerry Brunk
Board Member
people
Kadir Kadhiresan
Board Member

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Funding Insights of HistoSonics

HistoSonics has successfully raised a total of $565.73M across 11 strategic funding rounds. The most recent funding activity was a Series E round of $250 million completed in October 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 11
  • Last Round Series E — $250.0M
  • First Round

    (16 May 2014)

  • Investors Count 21
Date Amount Transaction Name Valuation Lead Investors Investors
Oct, 2025 Amount Series E - HistoSonics Valuation

investors

Jul, 2024 Amount Series D - HistoSonics Valuation Alpha Wave Global
Dec, 2022 Amount Series D - HistoSonics Valuation Johnson & Johnson Innovation
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Investors in HistoSonics

HistoSonics has secured backing from 24 investors, including venture fund, institutional, and angel investors. Prominent investors backing the company include Varian, University of Michigan and Fletcher Spaght. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Angel
Investor Description Founded Year Domain Location
Venture capital firm focused on growth-stage companies
Founded Year Domain Location
Amzak Health is engaged in venture investments in life sciences.
Founded Year Domain Location
Investments are focused on tech and life sciences startups.
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by HistoSonics

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016

Financial Statements - HistoSonics

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Histosonics Comparisons

Employees
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Competitors of HistoSonics

HistoSonics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Insightec, Profound Medical, Theraclion, Carthera and SONIRE Therapeutics, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
MR-interfaced ultrasound devices for cancer and neurology treatments are provided.
domain founded_year HQ Location
Image-guided prostate ablation systems for cancer treatment are developed.
domain founded_year HQ Location
Provider of non-invasive robotic ultrasound therapy devices
domain founded_year HQ Location
Ultrasound-based medical devices for brain tumor treatment are developed.
domain founded_year HQ Location
High-intensity focused ultrasound systems for targeted cancer treatments are developed.
Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

Latest news on Histosonics

Frequently Asked Questions about HistoSonics

When was HistoSonics founded?

HistoSonics was founded in 2009 and raised its 1st funding round 5 years after it was founded.

Where is HistoSonics located?

HistoSonics is headquartered in Ann Arbor, United States. It is registered at Ann Arbor, Michigan, United States.

Who is the current CEO of HistoSonics?

Mike Blue is the current CEO of HistoSonics.

Is HistoSonics a funded company?

HistoSonics is a funded company, having raised a total of $565.73M across 11 funding rounds to date. The company's 1st funding round was a Series D of $85M, raised on May 16, 2014.

How many employees does HistoSonics have?

As of Dec 31, 2022, the latest employee count at HistoSonics is 56.

What does HistoSonics do?

HistoSonics was founded in 2009 in Ann Arbor, United States, and focuses on medical technology within the ultrasound therapeutics sector. Histotripsy technology, licensed from the University of Michigan, is developed as a non-invasive, image-guided system that uses pulsed sound waves to create cavitation for mechanical tissue destruction at the cellular level. Applications span cardiovascular, oncology, neurology, and urology fields, targeting tumors, plaque, and other tissues.

Who are the top competitors of HistoSonics?

HistoSonics's top competitors include Insightec, Profound Medical and Theraclion.

What products or services does HistoSonics offer?

HistoSonics offers Histotripsy System and Clinical Trials Platform.

Who are HistoSonics's investors?

HistoSonics has 24 investors. Key investors include Varian, University of Michigan, Fletcher Spaght, Signature NY, and Early Stage Partners.

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