About HistoSonics
HistoSonics is a Healthcare company based in Ann Arbor (United States) founded in 2009, and was acquired by K5 Global in August 2025. Tissue ablation is achieved through non-invasive ultrasound Histotripsy technology. HistoSonics has raised $565.73 million across 12 funding rounds from investors including Varian, University of Michigan and Fletcher Spaght. The company has 56 employees. Its chief executive, as recorded, is Mike Blue. Its website histosonics.com draws about 15 thousand monthly visits. HistoSonics offers products and services including Histotripsy System and Clinical Trials Platform. Its focus areas include Life Sciences, Oncology, Medical Devices and Therapies. Its legal entity is HISTOSONICS, INC ATTN CHRISTINE.
Company details
HistoSonics was founded in 2009 in Ann Arbor, United States, and focuses on medical technology within the ultrasound therapeutics sector. Histotripsy technology, licensed from the University of Michigan, is developed as a non-invasive, image-guided system that uses pulsed sound waves to create cavitation for mechanical tissue destruction at the cellular level. Applications span cardiovascular, oncology, neurology, and urology fields, targeting tumors, plaque, and other tissues.
- Headquarters Ann Arbor, United States
- Employees 56
- Stage Acquired
- SectorsHealthcare
- Email••••••••
- Website histosonics.com
- Social LinkedIn X Facebook
- Acquired by K5 Global (Aug 2025)
- Legal Name Histosonics, Inc Attn Christine
Products & Services of HistoSonics
HistoSonics offers a comprehensive portfolio of products and services, including Histotripsy System and Clinical Trials Platform.
Non-invasive platform for mechanical destruction of liver tumors.
System for testing histotripsy in oncology applications.
Funding Insights of HistoSonics
HistoSonics has successfully raised a total of $565.73M across 12 strategic funding rounds. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.
- Total Funding $565.73M
- Total Rounds 12
- First Round $14.17M
(May 2014)
- Investors Count 24
Latest 10 of 12 funding rounds of HistoSonics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jun 2026 | Series E | – | – | ||
| Oct 2025 | $250M | Series E | – | – | |
| Jul 2024 | $102M | Series D | – | Alpha Wave Global | |
| Dec 2022 | $85M | Series D | – | Johnson & Johnson Innovation | |
| Nov 2020 | $15M | Debt – Conventional | – | – | |
| Jun 2020 | $40.76M | Series C | – | Yonjin Capital | |
| Apr 2019 | $54M | Series C | – | Varian Medical Systems | |
| Feb 2019 | $7M | Series B | – | – | – |
| Feb 2017 | $8.3M | Series B | – | Venture Investors | |
| Jul 2015 | $3M | Series A | – | – |
27 investors in total: 26 institutional and 1 angel.
Investors in HistoSonics
HistoSonics has secured backing from 27 investors, including venture fund, institutional, and angel investors. Prominent investors backing the company include Varian, University of Michigan and Fletcher Spaght.
| Investor | Description | Founded Year | Domain | Location |
|---|---|---|---|---|
Venture capital firm focused on growth-stage companies | alphawaveglobal.com | New York, United States | ||
Amzak Health is engaged in venture investments in life sciences. | amzakhealth.com | New York, United States | ||
Investments are focused on tech and life sciences startups. | healthquestcapital.com | Belmont, United States | ||
Multiple sectors focused seed & early stage VC firm investing in the US, Europe & Asia | ventureinvestors.com | Madison, United States | ||
Lumira Ventures is engaged in life sciences venture capital investment. | lumiraventures.com | Toronto, Canada | ||
Venture capital firm backed by Yongjin Group | yjventure.com | Cambridge, United States | ||
Tech & Life Sciences focused VC firm investing in early stage companies in the US & Europe | hatterasvp.com | Durham, United States | ||
Early-stage investments in US tech companies are made. | 2001 | esplp.com | Cleveland, United States | |
Grand Angels is engaged in angel investing for startups. | 2005 | grandangels.org | Grand Rapids, United States | |
| zli.umich.edu/wolverine-venture-fund |
Investor details for HistoSonics
The complete investor list, round-by-round participation and investor portfolios require an active premium plan.
- Complete investor list
- Round participation
- Investor portfolios
- Co-investor network
Verified entity values are shown only after access is granted.
People of HistoSonics
99 people are tracked at HistoSonics (33 in leadership, 7 in board & advisors, 59 in team); the tracked headcount is 56.
| Name | Role | Group |
|---|---|---|
Mike Blue | CEO | Leadership |
David Krenn | Chief Financial Officer | Leadership |
Joseph Herman | Medical Director | Leadership |
Trey Thomas | Area Sales Director - Eastern US | Leadership |
Alex Perez | Director Of Education | Leadership |
Josh Stopek | VP of Research & Development | Leadership |
Michele Bossert | VP of Education | Leadership |
Josh King | VP of Marketing | Leadership |
Eric Clyse | Vice President Operations | Leadership |
Geoff Gleason | Director, Clinical Operations | Leadership |
David Vershum | R&d Director - Embedded Systems | Leadership |
Michael Hodgkiss | Area Sales Director | Leadership |
Michael Pastrick | Sr. Director, Finance | Leadership |
Lisa Lapenna | Area Sales Director | Leadership |
Justin Grumbir | Director Of R&d | Leadership |
Nicole Brough | Director, Clinical Education | Leadership |
Jaime Kean | Director, Clinical Study Design And Planning | Leadership |
Jonathan Cannata | Sr. Director Of Research And Advanced Development | Leadership |
Donald Hayden | Vice President Of Global Sales | Leadership |
Scott Fehsenfeld | Area Sales Director | Leadership |
79 more people are available in the full profile.
Complete people profiles for HistoSonics
Full employee and board profiles, team structure, tenure and professional contact details require an active premium plan.
- Full employee list
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Timeline of HistoSonics
4 dated milestones of HistoSonics across 17 years, from founding to its latest funding, stage changes and deals.
- Founded HistoSonics is founded.
- Funding First funding round of $14.2M.
- Exit Acquired by K5 Global.
- Funding Latest funding round, Series E,.
Web traffic of HistoSonics
The website of HistoSonics (histosonics.com) receives about 14.7K visits a month.
- Monthly visits14.7K
▲ 13.7% vs previous month
Websites whose visitors overlap most with HistoSonics. Affinity shows how closely the audiences match.
| Website | Domain | Audience affinity | Monthly visits | Global rank | Profile |
|---|---|---|---|---|---|
fusfoundation.org | fusfoundation.org | 100% | #593,619 | – | |
| clinipace.com | 77% | View details | |||
| phasebio.com | 77% | 2.2K | #11,529,454 | View details | |
| fiercebiotech.com | 40% | 858.3K | #81,022 | View details |
Top companies in Oncology
3 companies that operate in the same segment as HistoSonics (Oncology) in United States, ranked by their profile score on The Company Check.
| Company | Description | Founded | Location | Total funding | Revenue | Employees |
|---|---|---|---|---|---|---|
mRNA-based therapeutics for diseases including cancer and infections are developed. | 2010 | Cambridge, Massachusetts, United States | USD 2.78 B | USD 1.94 B | 5,800 | |
Digital sequencing technology for cancer detection is developed. | 2012 | Redwood City, California, United States | USD 557.5 M | USD 982.02 M | 4,867 | |
Circulating tumor DNA is screened for early cancer detection. | 2016 | Menlo Park, California, United States | USD 2 B | USD 147.17 M | 1,141 |
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Related news about Histosonics
Complete news archive for HistoSonics
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Frequently Asked Questions about HistoSonics
HistoSonics was founded in 2009 and raised its 1st funding round 5 years after it was founded.
HistoSonics is headquartered in Ann Arbor, United States. It is registered at Ann Arbor, Michigan, United States.
Mike Blue is the CEO of HistoSonics, as recorded in our data.
HistoSonics is a funded company, having raised a total of $565.73M across 12 funding rounds to date. The company's 1st funding round was a Series A of $3M, raised on May 2014.
HistoSonics has 56 employees.
HistoSonics was founded in 2009 in Ann Arbor, United States, and focuses on medical technology within the ultrasound therapeutics sector. Histotripsy technology, licensed from the University of Michigan, is developed as a non-invasive, image-guided system that uses pulsed sound waves to create cavitation for mechanical tissue destruction at the cellular level. Applications span cardiovascular, oncology, neurology, and urology fields, targeting tumors, plaque, and other tissues.
HistoSonics offers Histotripsy System and Clinical Trials Platform.
HistoSonics has 27 investors. Key investors include Varian, University of Michigan, Fletcher Spaght, Signature NY, and Early Stage Partners.
HistoSonics operates through Histosonics, Inc Attn Christine.
Yes. HistoSonics was acquired by K5 Global in August 2025.