HotSpot Therapeutics

Boston, United States Founded: 2017 • Age: 9 yrs
Developer of a platform for protein function analysis

About HotSpot Therapeutics

HotSpot Therapeutics is a Healthcare company based in Boston (United States) founded in 2017. Developer of a platform for protein function analysis. HotSpot Therapeutics has raised $210 million across 3 funding rounds from investors including Atlas Venture, Revelation Partners and Life Sciences Partners. The company has 37 employees. HotSpot Therapeutics offers products and services including Smart Allosteryâ„¢ Platform. Its focus areas include HealthTech, Life Sciences Tech, Research & Development and Drug Discovery. Its legal entity is HOTSPOT THERAPEUTICS INC. Its competitors include Insitro, Certara and GRO Biosciences; 2 of its 3 listed competitors have raised funding.

Company details

HotSpot Therapeutics offers a proprietary platform for protein structure-function analysis. The company has developed the proprietary technology platform used to analyze the allosteric druggable sites on the regulatory proteins required for its function using novel compounds.

  • Headquarters Boston, United States
  • Employees 37
  • Sectors
    Healthcare
  • Email
    ••••••••
  • Phone
    •••• ••••
  • Website hotspotthera.com
  • Social LinkedIn X
  • Legal Name Hotspot Therapeutics Inc
Key Metrics
  • Total Equity Funding
    $210M (USD)

    in 3 rounds

  • Latest Funding Round
    $100M (USD), Series C

    Nov 2021

  • Investors
  • Employee Count
    37

Products & Services of HotSpot Therapeutics

HotSpot Therapeutics offers a comprehensive portfolio of products and services, including Smart Allostery™ Platform.

Smart Allostery™ Platform
Drug Discovery Platform

Integrates AI, pharmacology, and chemistry for allosteric medicine development.

Funding Insights of HotSpot Therapeutics

HotSpot Therapeutics has successfully raised a total of $210M across 3 strategic funding rounds. The most recent funding activity was a Series C round of $100 million completed in November 2021. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $210M
  • Total Rounds 3
  • Last Round Series C — $100M
  • First Round $45M

    (Jul 2018)

  • Investors Count 14

All 3 funding rounds of HotSpot Therapeutics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Nov 2021$100MSeries C–Pivotal bioVenture Partners
May 2020$65MSeries B–SR One
Jul 2018$45MSeries A–Atlas Venture, Sofinnova Partners
–
Valuation history

14 investors in total: 14 institutional.

Investors in HotSpot Therapeutics

HotSpot Therapeutics has secured backing from 14 investors, including institutional and venture fund investors. Prominent investors backing the company include Atlas Venture, Revelation Partners and Life Sciences Partners.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Venture capital firm investing in life science and biotechnology sectors
1980atlasventure.comCambridge, United States
Sofinnova Partners is focused on life sciences and healthcare investments.
sofinnovapartners.comParis, France
Private equity investments in life sciences businesses are managed.
1998lspvc.comAmsterdam, Netherlands
A biotechnology venture capital firm investing in innovative science.
srone.com
Growth-stage companies are invested in by this venture capital fund.
pavilioncapital.comNew York, United States
Multistage investments are directed toward technology, healthcare, and climate sectors.
b.capitalManhattan Beach, United States
Seed and early-stage therapeutics companies are invested in by MRLV.
mrlv.comCambridge, United States
Venture capital firm focused on healthcare startups
solasta-ventures.comBoston, United States
Brace Pharma Capital is focused on investing in innovative therapies.
bracepharma.comAtlanta, United States
Diversified investment management services are provided to clients.
2011monasheecap.comBoston, United States
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Investor details for HotSpot Therapeutics

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People of HotSpot Therapeutics

51 people are tracked at HotSpot Therapeutics (16 in leadership, 25 in board & advisors, 10 in team); the tracked headcount is 37.

NameRoleGroup
Dr. Stephan Hegge
Vice President Corporate StrategyLeadership
Jonathan Montagu
Co-Founder & CEOLeadership
Nisha Perez
Head Of DMPK And Clinical PharmacologyLeadership
Eva Jack
COOLeadership
Geraldine Harriman
Co-Founder & CSOLeadership
Natalie Wildenradt
Senior Director, Investor Relations, Public Relations & Corporate DevelopmentLeadership
Joe Wahle
Svp, Head Of ImmunologyLeadership
Taeg Kim
Director, ImmunologyLeadership
Wei Liu
Vp, Data Science And Platform BiologyLeadership
Nuruddeen Lewis
Senior Director, ImmunologyLeadership
Brian Hamman
Executive Director, Chemical BiologyLeadership
Emma W.
Vice President, CMC And Quality AssuranceLeadership
Fang Wang
Senior Vice PresidentLeadership
Kimberly Robell
Director, Translational SciencesLeadership
Evan Friedman
Vice President, Development OperationsLeadership
Yi Yao
Senior DirectorLeadership
Dan Grau
AdvisorBoard & advisors
Nicholas Keen
AdvisorBoard & advisors
Kevin Koch
AdvisorBoard & advisors
Jo Viney
AdvisorBoard & advisors

31 more people are available in the full profile.

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Timeline of HotSpot Therapeutics

3 dated milestones of HotSpot Therapeutics across 4 years, from founding to its latest funding, stage changes and deals.

  1. Founded HotSpot Therapeutics is founded.
  2. Funding First funding round of $45.0M.
  3. Funding Latest funding round, Series C, of $100.0M.

Competitors of HotSpot Therapeutics

HotSpot Therapeutics has 3 listed competitors in our database, 2 of them funded. They include Insitro, Certara and GRO Biosciences.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
insitro.com2018San Francisco, United States$643.21M257
An AI-enabled platform is developed for infectious disease treatment.
certara.com2008Princeton, United States827
Provider of a platform for in silico drug discovery and consulting services
grobio.com2016Boston, United States$91.15M22
Synthetic biology tools are developed via genetic code recoding techniques.
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Detailed competitors of HotSpot Therapeutics

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Web traffic of HotSpot Therapeutics

The website of HotSpot Therapeutics (hotspotthera.com) receives about 1.8K visits a month.

  • Monthly visits
    1.8K

    ▲ 15.6% vs previous month

Top companies in Life Sciences Platforms & Tools

3 companies that operate in the same segment as HotSpot Therapeutics (Life Sciences Platforms & Tools) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
Medidata is recognized as a leading provider of SaaS solutions for clinical research.
1999New York, New York, United StatesUSD 41.5 M
AI-based solutions for health management are provided.
2015Dallas, Texas, United StatesUSD 2.8 B1,111
Real-world health data is provided for research and decisions.
2012Menlo Park, California, United StatesUSD 259.16 M
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Related news about Hotspot Therapeutics

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Frequently Asked Questions about HotSpot Therapeutics

HotSpot Therapeutics was founded in 2017 and raised its 1st funding round 1 year after it was founded.

HotSpot Therapeutics is headquartered in Boston, United States. It is registered at Boston, Massachusetts, United States.

HotSpot Therapeutics is a funded company, having raised a total of $210M across 3 funding rounds to date. The company's 1st funding round was a Series A of $45M, raised on Jul 2018.

HotSpot Therapeutics has 37 employees.

HotSpot Therapeutics offers a proprietary platform for protein structure-function analysis. The company has developed the proprietary technology platform used to analyze the allosteric druggable sites on the regulatory proteins required for its function using novel compounds.

HotSpot Therapeutics's top competitors include Insitro, Certara and GRO Biosciences.

HotSpot Therapeutics offers Smart Allosteryâ„¢ Platform.

HotSpot Therapeutics has 14 investors. Key investors include Atlas Venture, Revelation Partners, Life Sciences Partners, Tekla Capital Management, and Monashee Investment Management.

HotSpot Therapeutics operates through Hotspot Therapeutics Inc.

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