About ISTO Biologics
ISTO Biologics is a company based in St. Louis (United States) founded in 1997.. ISTO Biologics has raised $50.76 million across 15 funding rounds from investors including HHS, NIST and Life Sciences Partners. ISTO Biologics has completed 3 acquisitions, including Progenicare, TheraCell and Theracell. ISTO Biologics offers products and services including Magellan®, Influx™, InQu®, and Precise™. ISTO Biologics operates in a competitive market with competitors including Kuros Biosciences, OssDsign, BONESUPPORT, Askel Healthcare and Renovos, among others.
- Headquarter St. Louis, United States
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Sectors
Healthcare
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Phone
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Website
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Social
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- Legal Name Isto Technologies Ii, Llc,
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Annual Revenue
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Net Profit
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EBITDA
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Total Equity Funding
$50.76 M (USD)
in 15 rounds
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Latest Funding Round
$1.2 M (USD), Grant
Jul 29, 2015
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Investors
HHS
& 6 more
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Employee Count
Employee Count
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Investments & Acquisitions
Progenicare
& 2 more
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Products & Services of ISTO Biologics
ISTO Biologics offers a comprehensive portfolio of products and services, including Magellan®, Influx™, InQu®, and Precise™. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.
Device for creating platelet-rich plasma and bone marrow therapies.
Allograft products for bone grafting and tissue repair.
Biosynthetic bone graft for faster fusion and healing.
System for targeted leukocyte-rich or poor platelet-rich plasma.
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Funding Insights of ISTO Biologics
ISTO Biologics has successfully raised a total of $50.76M across 15 strategic funding rounds. The most recent funding activity was a Grant round of $1.2 million completed in July 2015. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.
- Total Funding Total Funding
- Total Rounds 15
- Last Round Grant — $1.2M
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First Round
First Round
(12 Oct 2001)
- Investors Count 7
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
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| Jul, 2015 | Amount | Grant - ISTO Biologics | Valuation |
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| Jul, 2015 | Amount | Grant - ISTO Biologics | Valuation |
investors |
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| Dec, 2014 | Amount | Series E - ISTO Biologics | Valuation |
investors |
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| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
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| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
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Investors in ISTO Biologics
ISTO Biologics has secured backing from 7 investors, including venture fund and institutional investors. Prominent investors backing the company include HHS, NIST and Life Sciences Partners. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.
| Investor | Description | Founded Year | Domain | Location |
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Life-Sciences focused early & growth stage VC firm investing in the US & Europe
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Private equity investments in life sciences businesses are managed.
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Founded Year | Domain | Location |
| Investor | Description | Founded Year | Domain | Location |
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Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
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Founded Year | Domain | Location | |
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Startup ecosystems are ignited through strategic investments by Signite Partners.
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Founded Year | Domain | Location | |
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Venture capital is directed toward companies in multiple sectors.
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Founded Year | Domain | Location | |
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Venture capital is invested in cybersecurity, fintech, and AI startups.
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Founded Year | Domain | Location |
Investments & Acquisitions by ISTO Biologics
ISTO Biologics has strategically engaged in corporate development activities, having acquired 3 companies. Notable acquisitions include Progenicare, TheraCell and Theracell. These strategic investments and acquisitions demonstrate the company's commitment to growth through portfolio expansion, market consolidation, technology integration, and strategic partnerships that enhance competitive positioning and drive long-term value creation.
| Company Name | Description | Domain | Location | Founded Year | Amount |
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Bionic investment advisor platform
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2016 | ||||
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Fine Asian gourmet food is offered by an internet-first restaurant.
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2016 | ||||
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Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
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2014 | ||||
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Fine Asian gourmet food is offered by an internet-first restaurant.
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2016 |
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Stem cell therapies for regenerative healthcare needs are developed.
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2012 | ||||
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Cell and gene therapy products and orthopedic services are provided.
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2008 | ||||
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Allograft solutions for spinal surgery are provided by TheraCell.
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2008 |
| Company Name | Description | Domain | Location | Founded Year | Amount |
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OVO is recognized as a smart digital payment application.
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2017 | ||||
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Bionic investment advisor platform
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2016 | ||||
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Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
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2014 | ||||
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Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
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2014 |
Financial Statements - ISTO Biologics
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
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| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
Isto Biologics Comparisons
Competitors of ISTO Biologics
ISTO Biologics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Kuros Biosciences, OssDsign, BONESUPPORT, Askel Healthcare and Renovos, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.
| Company Name | Domain | Founded year | HQ Location | Description |
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| domain | founded_year | HQ Location |
Provider of smart solutions for bone disease management
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| domain | founded_year | HQ Location |
Developer of regenerative 3D-printed orthopedic implants for craniofacial bone defects and trauma
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| domain | founded_year | HQ Location |
Injectable synthetic bone substitutes are developed for fracture treatment.
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| domain | founded_year | HQ Location |
Regenerative medicines for cartilage and bone tissue regeneration are developed.
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| domain | founded_year | HQ Location |
Renovos is focused on regenerative medicine and therapeutic delivery.
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| Company Name | Domain | Founded year | HQ Location | Description |
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| domain | founded_year | HQ Location |
Multiple services are booked via an app-based platform.
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| domain | founded_year | HQ Location |
On-demand services are booked through an app-based platform.
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| domain | founded_year | HQ Location |
App based platform offering on demand delivery and ride-hailing services
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| domain | founded_year | HQ Location |
Operates an on-demand hyperlocal delivery app for food and groceries.
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Latest news on Isto Biologics
Frequently Asked Questions about ISTO Biologics
When was ISTO Biologics founded?
ISTO Biologics was founded in 1997 and raised its 1st funding round 4 years after it was founded.
Where is ISTO Biologics located?
ISTO Biologics is headquartered in St. Louis, United States. It is registered at St. Louis, Missouri, United States.
Is ISTO Biologics a funded company?
ISTO Biologics is a funded company, having raised a total of $50.76M across 15 funding rounds to date. The company's 1st funding round was a Series E of $2.46M, raised on Oct 12, 2001.
What does ISTO Biologics do?
ISTO Biologics is an orthobiologics company developing treatments for cartilage and bone repair. Orthobiologics is a technique that uses a combination of biomaterials and cell-based therapies to promote healing and repair tissues. In biomaterials, ISTOs patented biosynthetic platform uses a mixture of synthetic polylactide-co-glycolide (PLGA) and hyaluronic acid (HyA) to make tissue scaffolds. This PLGAHyA combination scaffold supports bone formation. Their 2nd product is Influx, which is an osteoinductive bone graft, made of demineralized human trabecular bone, for spinal fusions and orthopedic applications. Their 3rd product line is called CellPoint and is a concentrated Bone Marrow aspirate system. The kit includes a cell separation kit and the accessories required to aspirate and concentrate bone marrow.
Who are the top competitors of ISTO Biologics?
ISTO Biologics's top competitors include BONESUPPORT, OssDsign and Kuros Biosciences.
What products or services does ISTO Biologics offer?
ISTO Biologics offers Magellan®, Influx™, InQu®, and Precise™.
How many acquisitions has ISTO Biologics made?
ISTO Biologics has made 3 acquisitions, including Progenicare, TheraCell, and Theracell.
Who are ISTO Biologics's investors?
ISTO Biologics has 7 investors. Key investors include HHS, NIST, Life Sciences Partners, NIH SBIR/STTR, and USPTO.