iTeos Therapeutics

Cambridge, United States Founded: 2011 • Age: 15 yrs Listed Acquired By Concentra Biosciences
Anti-cancer immunotherapies are developed targeting tumor micro-environment.

About iTeos Therapeutics

iTeos Therapeutics is a Healthcare company based in Cambridge (United States) founded in 2011, and was acquired by Concentra Biosciences in July 2025. Anti-cancer immunotherapies are developed targeting tumor micro-environment. iTeos Therapeutics has raised $204.31 million across 9 funding rounds from investors including Pfizer, Janus Henderson Investors and RTW Investments. The company has 32 employees. iTeos Therapeutics offers products and services including Belrestotug (EOS-448), EOS-984, and EOS-215. Its focus areas include Life Sciences, Immunotherapy, Small Molecule and Immunosuppressive Pathway Inhibitors. Its legal entity is iTeos Therapeutics Inc. Its competitors include C4 Therapeutics, Erasca and MiRagen; 3 of its 3 listed competitors have raised funding.

Company details

iTeos Therapeutics was founded in 2011 and is based in Cambridge, United States. Focus is placed on immuno-oncology within the biotechnology sector, where anti-cancer agents are developed to address immuno-metabolism and immunosuppressive cells in the tumor microenvironment. Operations center on advancing a pipeline that includes an Adenosine A2A receptor antagonist currently in early-phase clinical trials, along with a TIGIT immune checkpoint blocking antibody.

Key Metrics
  • Annual Revenue
    $35 M (USD)
    178
    as on Dec 31, 2024
  • Net Profit
    -$134.41 M (USD)
    -19
    as on Dec 31, 2024
  • EBITDA
    -$159.53 M (USD)
    -6
    as on Dec 31, 2024
  • Total Equity Funding
    $204.31M (USD)

    in 9 rounds

  • Latest Funding Round
    $125.36M (USD), Series B

    Apr 2020

  • Investors
    Pfizer

    & 19 more

  • Employee Count
    32
  • Acquired by

Products & Services of iTeos Therapeutics

iTeos Therapeutics offers a comprehensive portfolio of products and services, including Belrestotug (EOS-448), EOS-984, and EOS-215.

Belrestotug (EOS-448)
Immunotherapy Drug

Immunotherapy targeting immune checkpoints for cancer treatment.

EOS-984
Immunotherapy Drug

Drug candidate enhancing anti-tumor immune responses in trials.

EOS-215
Immunotherapy Drug

Under development for advanced malignancies in clinical studies.

Funding Insights of iTeos Therapeutics

iTeos Therapeutics has successfully raised a total of $204.31M across 9 strategic funding rounds. The most recent funding activity was a Series B round of $125.36 million completed in April 2020. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $204.31M
  • Total Rounds 9
  • Last Round Series B β€” $125.36M
  • First Round $7.81M

    (Dec 2011)

  • Investors Count 19

All 9 funding rounds of iTeos Therapeutics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Apr 2020$125.36MSeries B–RA Capital Management, Boxer Capital
Jan 2020$16.76MGrant––
–
Jun 2018$75MSeries B–MPM Capital
May 2016$1.13MGrant––
Dec 2015$3.2MGrant––
–
Apr 2015Grant––
Dec 2014Series A–SRIW
–
May 2012$3.96MSeries A–Ludwig Institute for Cancer Research, Life Sciences Research Partners
–
Dec 2011$7.81MGrant––
–
Valuation history

20 investors in total: 20 institutional.

Investors in iTeos Therapeutics

iTeos Therapeutics has secured backing from 20 investors, including institutional and venture fund investors. Prominent investors backing the company include Pfizer, Janus Henderson Investors and RTW Investments.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Biotech startups are funded by this venture capital firm.
boxercap.comSan Diego, United States
Life Sciences focused VC firm investing in the US
2010rtwfunds.comNew York, United States
Multiple sectors are targeted for venture capital investments.
1934janushenderson.comLondon, United Kingdom
Long-term private equity investments in transformational opportunities are pursued.
invus.comNew York, United States
Late-stage life sciences investments are managed via VC and PE.
hbmpartners.comZug, Switzerland
Life-Sciences focused early and growth stage VC firm funding companies in China & the US
6dimensionscapital.comPudong, China
Buyouts are pursued by SRIW as a private equity firm.
sriw.beLiege, Belgium
Capital and talent are provided to biotech companies by Curative Ventures.
curativeventures.comDallas, United States
Fund+ is focused on investing in life sciences companies.
2019fundplus.beLeuven, Belgium
vivesfund.com
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Investor details for iTeos Therapeutics

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People of iTeos Therapeutics

38 people are tracked at iTeos Therapeutics (16 in leadership, 12 in board & advisors, 10 in team); the tracked headcount is 32.

NameRoleGroup
Philippe Brantegem
VP, Human ResourcesLeadership
Sandrine Segura Gozzini
Vp, Global Head Of CMCLeadership
Angela James
Vice President, Clinical DevelopmentLeadership
Michel Detheux
President & CEOLeadership
Matt Call
COOLeadership
David Feltquate
Chief Medical OfficerLeadership
Clarisse Truong-Maurin
Director, Lead Clinical Development ScientistLeadership
Olivier de Henau
Senior Medical DirectorLeadership
Steven Thys
Vice President Clinical OperationsLeadership
Benoit Dethy
Director Finance And AccountingLeadership
Prakash Bolleddula
Senior Director, Clinical PharmacologyLeadership
Gregory Driessens
Sr Director, Medicine Development LeadLeadership
Madhu Mawal-Dewan
Senior Director, Global Head Medical WritingLeadership
Michele Kelly
Senior Director Clinical QualityLeadership
Cédric Daems
Head Of Talent Acquisition & HR Business Partner Pre-clinical (director)Leadership
Erica Houthuys
Global Program Head, Eos-984 (director)Leadership
Aaron Davis
DirectorBoard & advisors
Tony Ho
DirectorBoard & advisors
Gordon Freeman
Chairman of the SABBoard & advisors
Derek Dirocco
DirectorBoard & advisors

18 more people are available in the full profile.

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Complete people profiles for iTeos Therapeutics

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Timeline of iTeos Therapeutics

5 dated milestones of iTeos Therapeutics across 14 years, from founding to its latest funding, stage changes and deals.

  1. Founded iTeos Therapeutics is founded.
  2. Funding First funding round of $7.8M.
  3. Funding Latest funding round, Series B, of $125.4M.
  4. IPO Lists on the stock exchange (IPO).
  5. Exit Acquired by Concentra Biosciences.

Competitors of iTeos Therapeutics

iTeos Therapeutics has 3 listed competitors in our database, 3 of them funded. They include C4 Therapeutics, Erasca and MiRagen.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
c4therapeutics.com2016Cambridge, United States$223M121
Small-molecule drugs for cancer treatment are developed via Degronimid platform.
erasca.com2018San Diego, United States$300M120
Small molecule therapeutics for cancer treatment are developed.
miragen.com2007Boulder, United States$111.29M92
MicroRNA-based therapeutics are developed for treating multiple diseases.
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Detailed competitors of iTeos Therapeutics

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Top companies in Immunology & Cancer Therapeutics

3 companies that operate in the same segment as iTeos Therapeutics (Immunology & Cancer Therapeutics) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Targeted and immune-oncology drugs for cancer treatment are developed.
2010Cambridge, Massachusetts, United StatesUSD 172 M
Immuno-modulatory therapies for dementia and neurodegenerative disorders are developed.
2013San Francisco, California, United StatesUSD 214.78 MUSD 21.05 M211
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Related news about Iteos Therapeutics

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Frequently Asked Questions about iTeos Therapeutics

iTeos Therapeutics was founded in 2011.

iTeos Therapeutics is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.

iTeos Therapeutics is a funded company, having raised a total of $204.31M across 9 funding rounds to date. The company's 1st funding round was a Grant of $7.81M, raised on Dec 2011.

iTeos Therapeutics has 32 employees.

Annual revenue of iTeos Therapeutics is $35M as on Dec 31, 2024.

iTeos Therapeutics was founded in 2011 and is based in Cambridge, United States. Focus is placed on immuno-oncology within the biotechnology sector, where anti-cancer agents are developed to address immuno-metabolism and immunosuppressive cells in the tumor microenvironment. Operations center on advancing a pipeline that includes an Adenosine A2A receptor antagonist currently in early-phase clinical trials, along with a TIGIT immune checkpoint blocking antibody.

iTeos Therapeutics's top competitors include C4 Therapeutics, Erasca and MiRagen.

iTeos Therapeutics offers Belrestotug (EOS-448), EOS-984, and EOS-215.

iTeos Therapeutics has 20 investors. Key investors include Pfizer, Janus Henderson Investors, RTW Investments, Bpifrance, and RA Capital.

iTeos Therapeutics operates through Iteos Therapeutics Inc.

Yes. iTeos Therapeutics was acquired by Concentra Biosciences in July 2025.

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