Keystone Heart

Tampa, United States Founded: 2004 • Age: 22 yrs Acquired By Venus MedTech
Embolic cerebral protection devices

About Keystone Heart

Keystone Heart is a Healthcare company based in Tampa (United States) founded in 2004, and was acquired by Venus MedTech in September 2018. It operates as an embolic cerebral protection devices. Keystone Heart has raised $14 million across 1 funding round from investors including Venus MedTech and Orbimed. Its focus areas include Life Sciences, Neurology, Medical Devices and Therapeutic Devices. Its competitors include Claret Medical, Emboline, Protembis, Synaptive Medical and Filterlex Medical and 4 more; 9 of its 9 listed competitors have raised funding.

Company details

Keystone Heart produces TriGuard, embolic cerebral protection devices to decrease the risk of stroke, neurocognitive decline and dementia caused by brain emboli during cardiovascular procedures such as Surgical valve replacement, Ablation for Atrial fibrillation, TAVR etc... The TriGuard device uses a self deploying and self positioning Nitinol frame and mesh to provide coverage to all three major blood vessels arising from the Aortic arch. TriGuard is not commercially available in USA as of June 2016.

Operational Areas
Key Metrics
  • Total Equity Funding
    $14M (USD)

    in 1 rounds

  • Latest Funding Round
    $14M (USD), Series B

    May 2014

  • Investors
  • Acquired by
    Venus MedTech

    (Sep 2018)

Funding Insights of Keystone Heart

Keystone Heart has successfully raised a total of $14M through 1 strategic funding round. The most recent funding activity was a Series B round of $14 million completed in May 2014. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $14M
  • Total Rounds 1
  • Last Round Series B β€” $14M
  • First Round $14M

    (May 2014)

  • Investors Count 1

All 1 funding rounds of Keystone Heart with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
May 2014$14MSeries B––
Valuation history

2 investors in total: 2 institutional.

Investors in Keystone Heart

Keystone Heart has secured backing from 2 investors, including venture fund investors. Prominent investors backing the company include Venus MedTech and Orbimed.

All
Venture Fund
InvestorDescriptionFounded YearDomainLocation
Investments are made by OrbiMed in global healthcare innovations across biopharmaceuticals and related fields.
1989orbimed.comNew York, United States
Transcatheter aortic and pulmonic valves are developed for cardiovascular procedures.
2009venusmedtech.comHangzhou, China
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Investor details for Keystone Heart

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Timeline of Keystone Heart

3 dated milestones of Keystone Heart across 14 years, from founding to its latest funding, stage changes and deals.

  1. Founded Keystone Heart is founded.
  2. Funding First funding round of $14.0M.
  3. Exit Acquired by Venus MedTech.

Competitors of Keystone Heart

Keystone Heart has 9 listed competitors in our database, 9 of them funded. They include Claret Medical, Emboline, Protembis, Synaptive Medical and Filterlex Medical, among others.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
claretmedical.com2009Santa Rosa, United States$47.76M105
Cerebral vascular protection systems for endovascular procedures are developed.
emboline.com2011Santa Cruz, United States$81.92M16
Aortic embolic protection devices are developed for cardiovascular procedures.
protembis.com2013Aachen, Germany$45.17M3
Manufacturer of cerebral protection device
synaptivemedical.com2012Toronto, Canada$76.83M–
Planning and imaging solutions for neurosurgery are developed.
filterlex.com2015Tel Aviv, Israel$16.89M–
Developer of an embolic protection device
embrella.net2007Malvern, United States$6.7M–
Embolic cerebral protection is enhanced for cardiovascular procedures.
transversemedical.com2011Golden, United States$26.77M–
Developer of a device to prevent stroke during transcatheter aortic valve replacement heart procedures
invictusmed.com2010San Antonio, United States$8.93M–
Pediatric medical devices for infant care are developed and explored.
neuramedica.com2014Oregon, United States$1.85M–
Bioabsorbable dural clips are developed for durotomy and spinal closures.
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Detailed competitors of Keystone Heart

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Top companies in Neurology

10 companies that operate in the same segment as Keystone Heart (Neurology), ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
Novel biopharmaceutical medicines are developed for unmet medical needs.
2003Dublin, IrelandUSD 265 MUSD 4.27 B2,800
Immuno-modulatory therapies for dementia and neurodegenerative disorders are developed.
2013San Francisco, California, United StatesUSD 214.78 MUSD 21.05 M211
Developer of therapeutics for psychiatric and neurologic diseases
2002New York, New York, United StatesUSD 80.87 MUSD 250.31 M600
Biologics platform developed for intracellular delivery in rare diseases.
2016Boston, Massachusetts, United StatesUSD 175.25 MUSD 25.42 M183
Developer of therapies for the treatment of musculoskeletal disorders
2007Woburn, Massachusetts, United StatesUSD 62 MUSD 85.55 M692
MR-interfaced ultrasound devices for cancer and neurology treatments are provided.
1999Tirat Carmel, Haifa District, IsraelUSD 574.2 M–541
AI-driven drug discovery platform for neurological diseases based on patients biomarkers
2019San Francisco, California, United StatesUSD 144.72 M–76
Small molecule drugs for rare diseases are developed.
1998South Plainfield, New Jersey, United StatesUSD 248.1 MUSD 1.73 B939
Developer of small molecule therapeutics for endocrine and CNS disorders
1992San Diego, California, United StatesUSD 10 MUSD 2.86 B1,800
Developer of antibodies to treat complement-mediated neurodegenerative diseases
2011San Francisco, California, United StatesUSD 256 M–100
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Related news about Keystone Heart

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Frequently Asked Questions about Keystone Heart

Keystone Heart was founded in 2004 and raised its 1st funding round 10 years after it was founded.

Keystone Heart is headquartered in Tampa, United States. It is registered at Tampa, Florida, United States.

Keystone Heart is a funded company, having raised a total of $14M across 1 funding round to date. The company's 1st funding round was a Series B of $14M, raised on May 2014.

Keystone Heart produces TriGuard, embolic cerebral protection devices to decrease the risk of stroke, neurocognitive decline and dementia caused by brain emboli during cardiovascular procedures such as Surgical valve replacement, Ablation for Atrial fibrillation, TAVR etc... The TriGuard device uses a self deploying and self positioning Nitinol frame and mesh to provide coverage to all three major blood vessels arising from the Aortic arch. TriGuard is not commercially available in USA as of June 2016.

Keystone Heart's top competitors include Protembis, Synaptive Medical and Emboline.

Keystone Heart has 2 investors. Key investors include Venus MedTech, and Orbimed.

Yes. Keystone Heart was acquired by Venus MedTech in September 2018.

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