Leap Therapeutics

Cambridge, United States Founded: 2011 • Age: 15 yrs
Novel immuno-oncology therapeutics are acquired and developed for clinical advancement.
Annual revenue - Latest available
Total funding $24.7M 7 rounds
Employees 52 Tracked headcount
Investors 4 Known backers
Products 3 Services tracked
Competitors 10 Brand Intelligence

About Leap Therapeutics

Leap Therapeutics is a company based in Cambridge (United States) founded in 2011. It operates as a HealthTech. Leap Therapeutics has raised $24.68 million across 7 funding rounds from investors including BeiGene, Perceptive Advisors and Healthcare Ventures. The company has 52 employees as of December 31, 2024. Leap Therapeutics has completed 1 acquisition, including Macrocure. Leap Therapeutics offers products and services including Sirexatamab (DKN-01), FL-301, and FL-501. Leap Therapeutics operates in a competitive market with competitors including Moderna, Jazz Pharmaceuticals, BeiGene, Advanced Accelerator Applications and Incyte, among others.

  • Headquarter Cambridge, United States
  • Employees 52 as on 31 Dec, 2024
  • Stage Public
  • Sectors
    Healthcare
  • Phone
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  • Website
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  • Social
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  • Legal Name Leap Therapeutics, Inc.
Operational Areas
Healthcare → Pharmaceuticals & Therapeutics Unlock Sub-Sector Unlock Segment
Healthcare → Healthcare Products & Supplies Unlock Sub-Sector Unlock Segment
Key Metrics
  • Annual Revenue
    Not available
  • Net Profit
    -$67.56 M (USD)
    17.02
    as on Dec 31, 2024
  • EBITDA
    -$70.05 M (USD)
    19.12
    as on Dec 31, 2024
  • Total Equity Funding
    $24.68 M (USD)

    in 7 rounds

  • Latest Funding Round
    $58.9 M (USD), Post-IPO

    Oct 06, 2025

  • Investors
    BeiGene

    & 3 more

  • Employee Count
    52

    as on Dec 31, 2024

  • Investments & Acquisitions
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IPO & Listings of Leap Therapeutics

Leap Therapeutics is a publicly listed company on the NASDAQ with ticker symbol LPTX in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

Exchange: NASDAQ · Ticker: LPTX · Sector: Health technology · USA

Products & Services of Leap Therapeutics

Leap Therapeutics offers a comprehensive portfolio of products and services, including Sirexatamab (DKN-01), FL-301, and FL-501.

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Primary

Targeted therapy developed for DKK1-expressing cancer tumors.

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Therapy developed for gastric and pancreatic cancer patients.

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Preclinical therapy targeting GDF-15 protein for cancer.

People of Leap Therapeutics

Headcount 10-50
Employee Profiles 15
Board Members and Advisors 1
Employee Profiles
People
Jonathan Miller
Vice President, Business Development & Finance
People
Mike Kagey
Vice President Of Translational Medicine
People
Abigail Guce-Merriam
Associate Director, CMC Downstream Development And Manufacturing
People
Steven Lam
Director Of Process Development And Manufacturing

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Board Members and Advisors
people
Christopher Mirabelli
Chairman

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Funding Insights of Leap Therapeutics

Leap Therapeutics has successfully raised a total of $24.68M across 7 strategic funding rounds. The most recent funding activity was a Post-IPO round of $58.9 million completed in October 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

Investors in Leap Therapeutics

Leap Therapeutics has secured backing from 4 investors, including venture fund and institutional investors. Prominent investors backing the company include BeiGene, Perceptive Advisors and Healthcare Ventures.

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Venture Fund
Institutional
Investor Description Founded Year Domain Location
Health-tech companies are targeted for venture capital investments.
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Venture capital investments are managed by Winklevoss brothers' family office.
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Investor details for Leap Therapeutics

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Investments & Acquisitions by Leap Therapeutics

Leap Therapeutics has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include Macrocure.

Investments
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Investment portfolio details for Leap Therapeutics

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Acquisitions
Company Name Description Domain Location Founded Year Amount
T-cell therapies for wound care are developed and commercialized.
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Complete acquisition details for Leap Therapeutics

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Financial Statements - Leap Therapeutics

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Detailed financials for Leap Therapeutics

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Leap Therapeutics Comparisons

Leap Therapeutics Primary company
Description
Novel immuno-oncology therapeutics are acquired and develope...
Location
Cambridge, United States
Founded Year
2011
Annual Revenue
Not available
Net Profit
-$67.56 M (USD)
EBITDA
-$70.05 M (USD)
Employees
52
As of 2024
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Peer comparison for Leap Therapeutics

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Competitors of Leap Therapeutics

Leap Therapeutics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Moderna, Jazz Pharmaceuticals, BeiGene, Advanced Accelerator Applications and Incyte, among others.

Company Name Domain Founded year HQ Location Description
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mRNA-based therapeutics for diseases including cancer and infections are developed.
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Novel biopharmaceutical medicines are developed for unmet medical needs.
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Targeted and immune-oncology drugs for cancer treatment are developed.
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Radiopharmaceuticals for oncology diagnostics and therapies are developed and marketed.
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Small molecules are developed for cancer and skin disease treatments.
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Cancer therapies are developed using selective pathway inhibitors.
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Detailed competitors of Leap Therapeutics

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Latest news on Leap Therapeutics

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Complete news archive for Leap Therapeutics

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Frequently Asked Questions about Leap Therapeutics

Leap Therapeutics was founded in 2011.

Leap Therapeutics is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.

Leap Therapeutics is a funded company, having raised a total of $24.68M across 7 funding rounds to date.

As of Dec 31, 2024, the latest employee count at Leap Therapeutics is 52.

Leap Therapeutics, Inc. is focused on the development of targeted and immuno-oncology therapeutics. The companys primary candidate, Sirexatamab (DKN-01), is a humanized monoclonal antibody targeting the Dickkopf-1 (DKK1) protein, being developed for patients with esophagogastric, gynecologic, and colorectal cancers. Additional programs include FL-301 for gastric and pancreatic cancer, and FL-501 targeting GDF-15 in preclinical stages. Solutions are aimed at addressing unmet needs in oncology through innovative therapies and combinations across multiple cancer types.

Leap Therapeutics's top competitors include Moderna, Jazz Pharmaceuticals and Advanced Accelerator Applications.

Leap Therapeutics offers Sirexatamab (DKN-01), FL-301, and FL-501.

Yes, Leap Therapeutics is publicly traded on NASDAQ under the ticker symbol LPTX.

Leap Therapeutics has made 1 acquisition, including Macrocure.

Leap Therapeutics has 4 investors. Key investors include BeiGene, Perceptive Advisors, Healthcare Ventures, and Winklevoss Capital.

The ticker symbol of Leap Therapeutics is LPTX on NASDAQ.

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