Lineage Cell Therapeutics

Carlsbad, United States Founded: 1990 • Age: 36 yrs Listed
Lineage Cell Therapeutics is focused on developing allogeneic cell therapies.

About Lineage Cell Therapeutics

Lineage Cell Therapeutics is a publicly listed company based in Carlsbad (United States) founded in 1990. Lineage Cell Therapeutics is focused on developing allogeneic cell therapies. It operates on a HealthTech model. Lineage Cell Therapeutics has raised $45.8 million across 22 funding rounds from investors including Juvenescence, State of California and HHS. The company has 77 employees. Lineage Cell Therapeutics has completed 4 acquisitions, including Asterias Biotherapeutics, Canadian Neighbor Pharmacy and Glycosan. Its chief executive, as recorded, is Brian Culley. Lineage Cell Therapeutics offers products and services including OpRegen and OPC1. Its focus areas include Biotechnology and Cell Therapy. Its legal entity is Lineage Cell Therapeutics, Inc. Its competitors include Revance Therapeutics, Dermavant and Sol-Gel Technologies; 3 of its 3 listed competitors have raised funding.

Company details

Lineage Cell Therapeutics is engaged in the development of novel allogeneic cell therapies targeting serious neurological and ophthalmic conditions. The company utilizes a proprietary cell-based technology platform for designing, manufacturing, and testing specialized human cells. These cells are intended to replace or support dysfunctional cells caused by degenerative diseases, aging, or traumatic injuries. Programs such as OpRegen for dry AMD and OPC1 for spinal cord injury are advanced internally or with strategic partners like Genentech to enhance therapeutic value and success probability in the healthcare sector.

  • Headquarters Carlsbad, United States
  • Employees 77
  • Stage Public
  • Sectors
    Healthcare
  • Website category Health · Biotechnology and Pharmaceuticals
  • Email
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  • Phone
    β€’β€’β€’β€’ β€’β€’β€’β€’
  • Website lineagecell.com
  • Social LinkedIn X Facebook YouTube
  • Legal Name Lineage Cell Therapeutics, Inc.
Key Metrics
  • Annual Revenue
    $14.56 M (USD)
    53.24
    as on Dec 31, 2025
  • Net Profit
    -$63.53 M (USD)
    -241.41
    as on Dec 31, 2025
  • EBITDA
    -$21.08 M (USD)
    -1.01
    as on Dec 31, 2025
  • Total Equity Funding
    $45.8M (USD)

    in 22 rounds

  • Investors
  • Employee Count
    77
  • Investments & Acquisitions

Products & Services of Lineage Cell Therapeutics

Lineage Cell Therapeutics offers a comprehensive portfolio of products and services, including OpRegen and OPC1.

OpRegen
Cell Therapy

Cell therapy developed for dry AMD treatment in patients.

OPC1
Cell Therapy

Cell therapy designed for spinal cord injury recovery.

Apps and channels of Lineage Cell Therapeutics

its YouTube channel Lineage Cell Therapeutics has 330 subscribers and 18 videos.

Lineage Cell Therapeutics
YouTube 330 subscribers 18 videos Nonprofits & Activism
Open channel

Videos from Lineage Cell Therapeutics

The most watched videos on Lineage Cell Therapeutics's YouTube channel, Lineage Cell Therapeutics (330 subscribers). Click a video to play it here.

OPC1 Patient Spotlight - Jake Javier - Part 1
2.8K views
How Lineage Cell Therapeutics is working to become a leader in cell transplant medicine
1.7K views
OPC1 Patient Spotlight - Chris Block - Part 1
1.2K views
Sonia Cohen's OpRegen Story
1.2K views

More on Lineage Cell Therapeutics.

Funding Insights of Lineage Cell Therapeutics

Lineage Cell Therapeutics has successfully raised a total of $45.8M across 22 strategic funding rounds. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $45.8M
  • Total Rounds 22
  • First Round $3.5M

    (May 2009)

  • Investors Count 4

Latest 10 of 22 funding rounds of Lineage Cell Therapeutics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Apr 2024Grant––
May 2023$50,000Grant––
Sep 2020$576,440Grant––
Aug 2020$24.6MPost-IPO––
Aug 2019$670,621Grant––
–
May 2019$2.52MGrant––
–
Jun 2018$743,345Grant––
–
May 2018$1.93MGrant––
–
Apr 2018$385,923Grant––
Sep 2017$2.23MGrant––
Valuation history

4 investors in total: 4 institutional.

Investors in Lineage Cell Therapeutics

Lineage Cell Therapeutics has secured backing from 4 investors, including institutional investors. Prominent investors backing the company include Juvenescence, State of California and HHS.

All
Institutional
InvestorDescriptionFounded YearDomainLocation
Access to government programs and development services is provided.
1997ca.govUnited States
Business development in Israel is supported by a government organization.
1965matimop.org.ilJerusalem, Israel
Public health and human services are overseen by HHS.
1953hhs.gov
Provider of proprietary ketone ester-based therapeutic drink for age-related disorders and metabolic health
2017juvlabs.comDublin, Ireland
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Investor details for Lineage Cell Therapeutics

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People of Lineage Cell Therapeutics

1 people are tracked at Lineage Cell Therapeutics (1 in leadership); the tracked headcount is 77.

NameRoleGroup
Brian Culley
CEOLeadership
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IPO & Listings of Lineage Cell Therapeutics

Lineage Cell Therapeutics is a publicly listed company on the AMEX with ticker symbol LCTX in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

  • IPO date08 Apr 2014
  • Listed onNYSEAMERICAN: LCTX
  • Listed entityLineage Cell Therapeutics, Inc.
  • Exchange sectorHealth technology
  • ISINUS53566P1093
  • Share price$0.91 (-4.8% on the day) · 2026-10-13
  • Market capitalisation$229.7M
  • EPS (diluted, trailing year)$-0.18
  • Volume (last session)1,784,674

Financials of Lineage Cell Therapeutics

Exchange-reported annual figures
YearRevenueNet incomeEBITDA
2025$14.6M-$63.5M-$21.1M
2024$9.5M-$18.6M-$20.9M
2023$8.9M-$21.5M-$24.0M
2022$14.7M-$26.3M-$21.8M
2021$3.9M-$43.0M-$48.8M
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Detailed financial statements for Lineage Cell Therapeutics

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Investments & Acquisitions by Lineage Cell Therapeutics

Lineage Cell Therapeutics has strategically engaged in corporate development activities, having acquired 4 companies. Notable acquisitions include Asterias Biotherapeutics, Canadian Neighbor Pharmacy and Glycosan.

Acquisitions
Company NameDescriptionDomainLocationFoundedAcquiredAmount
Developer of cell therapy programs to treat cancer and neurological diseases
asteriasbio.comFremont, United States2013Nov 2018β€’β€’β€’β€’
Canadian Neighbor Pharmacy is engaged in online distribution of generic medications.
asteriasbiotherapeutics.comMenlo Park, United States2012Nov 2018β€’β€’β€’β€’
Bio-medical research services and genomic databases are provided by XenneX.
xennexinc.comCambridge, United States2003Apr 2012β€’β€’β€’β€’
Biocompatible hydrogels mimicking extracellular matrix are developed for tissue engineering.
glycosan.comAlameda, United States2006Feb 2011β€’β€’β€’β€’
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Complete acquisition details for Lineage Cell Therapeutics

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Timeline of Lineage Cell Therapeutics

8 dated milestones of Lineage Cell Therapeutics across 34 years, from founding to its latest funding, stage changes and deals.

  1. Founded Lineage Cell Therapeutics is founded.
  2. Funding First funding round of $3.5M.
  3. Acquisition Acquires Glycosan.
  4. Acquisition Acquires Xennex.
  5. IPO Lists on the stock exchange (IPO).
  6. Acquisition Acquires Asterias Biotherapeutics.
  7. Acquisition Acquires Canadian Neighbor Pharmacy.
  8. Funding Latest funding round, Grant,.

Competitors of Lineage Cell Therapeutics

Lineage Cell Therapeutics has 3 listed competitors in our database, 3 of them funded. They include Revance Therapeutics, Dermavant and Sol-Gel Technologies.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
revance.com2002Newark, United States$154.56M597
Neurotoxin products for aesthetic and therapeutic skin treatments are developed.
dermavant.com2016Phoenix, United States$160M
Small molecule therapeutics for inflammatory skin diseases are developed.
sol-gel.com1998United States$9M
Developing topical drug products for the treatment of rosacea, acne and interdigital tinea pedis.
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Detailed competitors of Lineage Cell Therapeutics

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Web traffic of Lineage Cell Therapeutics

The website of Lineage Cell Therapeutics (lineagecell.com) receives about 9.5K visits a month and ranks #2,352,150 among all websites worldwide, #3,216 in Biotechnology and Pharmaceuticals.

  • Monthly visits
    9.5K

    ▲ 16.1% vs previous month

  • Unique visitors
    3.8K

    per month

  • Global rank
    #2,352,150

    among all websites

  • Category rank
    #3,216

    Health · Biotechnology and Pharmaceuticals

Top companies in Orthopedics

3 companies that operate in the same segment as Lineage Cell Therapeutics (Orthopedics) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
Provider of high-frequency spinal cord stimulation implants
2006Menlo Park, California, United StatesUSD 154.1 MUSD 353.08 M1,215
Developer of therapies for the treatment of musculoskeletal disorders
2007Woburn, Massachusetts, United StatesUSD 62 MUSD 85.55 M692
Antibody-siRNA complexes are developed for cancer treatment.
2012San Diego, California, United StatesUSD 142.54 MUSD 10.9 M391
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Related news about Lineage Cell Therapeutics

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Frequently Asked Questions about Lineage Cell Therapeutics

Lineage Cell Therapeutics was founded in 1990 and raised its 1st funding round 19 years after it was founded.

Lineage Cell Therapeutics is headquartered in Carlsbad, United States. It is registered at Carlsbad, California, United States.

Brian Culley is the CEO of Lineage Cell Therapeutics, as recorded in our data.

Lineage Cell Therapeutics is a funded company, having raised a total of $45.8M across 22 funding rounds to date. The company's 1st funding round was a Grant of $2.23M, raised on May 2009.

Lineage Cell Therapeutics has 77 employees.

Annual revenue of Lineage Cell Therapeutics is $14.56M as on Dec 31, 2025.

Lineage Cell Therapeutics is engaged in the development of novel allogeneic cell therapies targeting serious neurological and ophthalmic conditions. The company utilizes a proprietary cell-based technology platform for designing, manufacturing, and testing specialized human cells. These cells are intended to replace or support dysfunctional cells caused by degenerative diseases, aging, or traumatic injuries. Programs such as OpRegen for dry AMD and OPC1 for spinal cord injury are advanced internally or with strategic partners like Genentech to enhance therapeutic value and success probability in the healthcare sector.

Lineage Cell Therapeutics's top competitors include Revance Therapeutics, Dermavant and Sol-Gel Technologies.

Lineage Cell Therapeutics offers OpRegen and OPC1.

Yes, Lineage Cell Therapeutics is publicly traded on AMEX under the ticker symbol LCTX.

Lineage Cell Therapeutics has made 4 acquisitions, including Asterias Biotherapeutics, Canadian Neighbor Pharmacy, and Glycosan.

Lineage Cell Therapeutics has 4 investors. Key investors include Juvenescence, State of California, HHS, and Israel Innovation Authority.

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