Lyell Immunopharma

San Francisco, United States Founded: 2018 • Age: 8 yrs
CAR-T and TIL immunotherapies for solid tumors are developed.
Annual revenue $61,000 Latest available
Total funding $493.0M 3 rounds
Employees 300 Tracked headcount
Investors 2 Known backers
Products 2 Services tracked
Competitors 9 Brand Intelligence

About Lyell Immunopharma

Lyell Immunopharma is a company based in San Francisco (United States) founded in 2018 by Rick Klausner. Lyell Immunopharma has raised $493 million across 3 funding rounds from investors including GSK and Sahsen Ventures. The company has 300 employees as of December 31, 2024. Lyell Immunopharma has completed 1 acquisition, including ImmPACT-Bio. Lyell Immunopharma offers products and services including LYL314 and CAR T-cell Therapies. Lyell Immunopharma operates in a competitive market with competitors including Poseida Therapeutics, Juno Therapeutics, TScan Therapeutics, Hummingbird Bioscience and Autolus, among others.

  • Headquarter San Francisco, United States
  • Employees 300 as on 31 Dec, 2024
  • Founders Rick Klausner
  • Stage Public
  • Sectors
    Healthcare
  • Phone
    Locked
  • Website
    Locked
  • Social
    Locked
  • Legal Name Lyell Immunopharma, Inc.
Operational Areas
Healthcare → Healthcare Products & Supplies Unlock Sub-Sector Unlock Segment
Healthcare → Pharmaceuticals & Therapeutics Unlock Sub-Sector Unlock Segment
Healthcare → Healthcare Products & Supplies Unlock Sub-Sector Unlock Segment
Key Metrics
  • Annual Revenue
    $61 K (USD)
    -53.08
    as on Dec 31, 2024
  • Net Profit
    -$342.99 M (USD)
    -46.18
    as on Dec 31, 2024
  • EBITDA
    -$204.26 M (USD)
    11.38
    as on Dec 31, 2024
  • Total Equity Funding
    $493 M (USD)

    in 3 rounds

  • Latest Funding Round
    $100 M (USD), Post-IPO

    Jul 25, 2025

  • Investors
    GSK

    & 1 more

  • Employee Count
    300

    as on Dec 31, 2024

  • Investments & Acquisitions
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IPO & Listings of Lyell Immunopharma

Lyell Immunopharma is a publicly listed company on the NASDAQ with ticker symbol LYEL in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

Exchange: NASDAQ · Ticker: LYEL · Sector: Health technology · USA

Products & Services of Lyell Immunopharma

Lyell Immunopharma offers a comprehensive portfolio of products and services, including LYL314 and CAR T-cell Therapies.

Product name locked
Category locked
Primary

Targets relapsed large B-cell lymphoma through advanced cell therapies

Product name locked
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Develops treatments for solid tumors and hematologic malignancies

People of Lyell Immunopharma

Headcount 200-500
Employee Profiles 60
Board Members and Advisors 9
Employee Profiles
People
Elizabeth Saccone M.b.a., Asq (Beth)
Head Of Business Operations & Program Management, Product Lead
People
Ryan M Smith
Director Of Procurement
People
Jessica Barragan
Researcher
People
James Cregg
Director Of Automation At Lyell Immunopharma

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Board Members and Advisors
people
Catherine Friedman
Director
people
Robert Nelsen
Director
people
William Rieflin
Director
people
Otis Brawley
Director

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Funding Insights of Lyell Immunopharma

Lyell Immunopharma has successfully raised a total of $493M across 3 strategic funding rounds. The most recent funding activity was a Post-IPO round of $100 million completed in July 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

Investors in Lyell Immunopharma

Lyell Immunopharma has secured backing from 2 investors, including institutional and venture fund investors. Prominent investors backing the company include GSK and Sahsen Ventures.

All
Venture Fund
Institutional
Investor Description Founded Year Domain Location
Investments in multiple sectors are made by Sahsen Ventures.
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Developer of pharmaceuticals and vaccines for various therapeutic areas
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Investor details for Lyell Immunopharma

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Investments & Acquisitions by Lyell Immunopharma

Lyell Immunopharma has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include ImmPACT-Bio.

Investments
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Investment portfolio details for Lyell Immunopharma

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Acquisitions
Company Name Description Domain Location Founded Year Amount
Biotechnology research and development are conducted in Israel.
Locked Locked 2017 Locked
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Complete acquisition details for Lyell Immunopharma

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Financial Statements - Lyell Immunopharma

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Detailed financials for Lyell Immunopharma

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Lyell Immunopharma Comparisons

Lyell Immunopharma Primary company
Description
CAR-T and TIL immunotherapies for solid tumors are developed...
Location
San Francisco, United States
Founded Year
2018
Annual Revenue
$61 K (USD)
Net Profit
-$342.99 M (USD)
EBITDA
-$204.26 M (USD)
Employees
300
As of 2024
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Peer comparison for Lyell Immunopharma

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Competitors of Lyell Immunopharma

Lyell Immunopharma operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Poseida Therapeutics, Juno Therapeutics, TScan Therapeutics, Hummingbird Bioscience and Autolus, among others.

Company Name Domain Founded year HQ Location Description
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Developer of gene therapies for treating cancer and liver orphan disease by using gene editing technologies
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CAR T-cell and T-cell receptor immunotherapies for cancer are developed.
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T cell-based treatments for immunological and oncological disorders are developed.
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Antibody drugs for cancer treatment are developed.
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Engineered T-cell immunotherapies are developed for cancer and auto-immune diseases.
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Detailed competitors of Lyell Immunopharma

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Latest news on Lyell Immunopharma

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Complete news archive for Lyell Immunopharma

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Frequently Asked Questions about Lyell Immunopharma

Lyell Immunopharma was founded in 2018.

Lyell Immunopharma is headquartered in San Francisco, United States. It is registered at San Francisco, California, United States.

Rick Klausner is the current CEO of Lyell Immunopharma. They have also founded this company.

Lyell Immunopharma is a funded company, having raised a total of $493M across 3 funding rounds to date.

As of Dec 31, 2024, the latest employee count at Lyell Immunopharma is 300.

Annual revenue of Lyell Immunopharma is $61K as on Dec 31, 2024.

Founded in 2018 and based in San Francisco, United States, the biotechnology firm focuses on oncology. CAR-T therapies are advanced for treating ROR1-positive non-small cell lung cancer and triple-negative breast cancer through the lead program LYL797. An autologous TIL therapy, LYL845, is pursued for multiple solid tumors. Operations center on clinical development of these immunotherapies to address unmet needs in cancer care.

Lyell Immunopharma's top competitors include Hummingbird Bioscience, Juno Therapeutics and Immatics.

Lyell Immunopharma offers LYL314 and CAR T-cell Therapies.

Yes, Lyell Immunopharma is publicly traded on NASDAQ under the ticker symbol LYEL.

Lyell Immunopharma has made 1 acquisition, including ImmPACT-Bio.

Lyell Immunopharma has 2 investors. Key investors include GSK, and Sahsen Ventures.

The ticker symbol of Lyell Immunopharma is LYEL on NASDAQ.

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