Lyell Immunopharma

San Francisco, United States Founded: 2018 • Age: 8 yrs
CAR-T and TIL immunotherapies for solid tumors are developed.
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About Lyell Immunopharma

Lyell Immunopharma is a company based in San Francisco (United States) founded in 2018 by Rick Klausner.. Lyell Immunopharma has raised $493 million across 3 funding rounds from investors including GSK and Sahsen Ventures. The company has 300 employees as of December 31, 2024. Lyell Immunopharma has completed 1 acquisition, including ImmPACT-Bio. Lyell Immunopharma offers products and services including LYL314 and CAR T-cell Therapies. Lyell Immunopharma operates in a competitive market with competitors including Poseida Therapeutics, Juno Therapeutics, TScan Therapeutics, Hummingbird Bioscience and Autolus, among others.

  • Headquarter San Francisco, United States
  • Employees 300 as on 31 Dec, 2024
  • Founders Rick Klausner
  • Stage Public
  • Sectors
    Healthcare
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Lyell Immunopharma, Inc.
Operational Areas
Healthcare → Healthcare Products & Supplies
Healthcare → Pharmaceuticals & Therapeutics
Healthcare → Healthcare Products & Supplies
Key Metrics
  • Annual Revenue
    $61 K
    -53.08
    as on Dec 31, 2024
  • Net Profit
    $-342.99 M
    -46.18
    as on Dec 31, 2024
  • EBITDA
    $-204.26 M
    11.38
    as on Dec 31, 2024
  • Total Equity Funding
    $493 M (USD)

    in 3 rounds

  • Latest Funding Round
    $100 M (USD), Post-IPO

    Jul 25, 2025

  • Investors
    GSK

    & 1 more

  • Employee Count
    300

    as on Dec 31, 2024

  • Investments & Acquisitions
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IPO & Listings of Lyell Immunopharma

Lyell Immunopharma is a publicly listed company on the NASDAQ with ticker symbol LYEL in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

Exchange: NASDAQ · Ticker: LYEL . Sector: Health technology · USA

Products & Services of Lyell Immunopharma

Lyell Immunopharma offers a comprehensive portfolio of products and services, including LYL314 and CAR T-cell Therapies. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.

Primary

Targets relapsed large B-cell lymphoma through advanced cell therapies

Develops treatments for solid tumors and hematologic malignancies

People of Lyell Immunopharma
Headcount 200-500
Employee Profiles 60
Board Members and Advisors 9
Employee Profiles
People
Elizabeth Saccone M.b.a., Asq (Beth)
Head Of Business Operations & Program Management, Product Lead
People
Ryan M Smith
Director Of Procurement
People
Jessica Barragan
Researcher
People
James Cregg
Director Of Automation At Lyell Immunopharma

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Board Members and Advisors
people
Catherine Friedman
Director
people
Robert Nelsen
Director
people
William Rieflin
Director
people
Otis Brawley
Director

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Funding Insights of Lyell Immunopharma

Lyell Immunopharma has successfully raised a total of $493M across 3 strategic funding rounds. The most recent funding activity was a Post-IPO round of $100 million completed in July 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 3
  • Last Round Post-IPO — $100.0M
  • First Round
  • Investors Count 2
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2025 Amount Post-IPO - Lyell Immunopharma Valuation

investors

Mar, 2020 Amount Series C - Lyell Immunopharma Valuation GSK
Jun, 2018 Amount Seed - Lyell Immunopharma Valuation Sahsen Ventures
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Investors in Lyell Immunopharma

Lyell Immunopharma has secured backing from 2 investors, including institutional and venture fund investors. Prominent investors backing the company include GSK and Sahsen Ventures. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Investor Description Founded Year Domain Location
Investments in multiple sectors are made by Sahsen Ventures.
Founded Year Domain Location
Developer of pharmaceuticals and vaccines for various therapeutic areas
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by Lyell Immunopharma

Lyell Immunopharma has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include ImmPACT-Bio. These strategic investments and acquisitions demonstrate the company's commitment to growth through portfolio expansion, market consolidation, technology integration, and strategic partnerships that enhance competitive positioning and drive long-term value creation.

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Acquisitions
Company Name Description Domain Location Founded Year Amount
Biotechnology research and development are conducted in Israel.
2017
Company Name Description Domain Location Founded Year Amount
OVO is recognized as a smart digital payment application.
2017
Bionic investment advisor platform
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014

Financial Statements - Lyell Immunopharma

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Lyell Immunopharma Comparisons

Employees
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Competitors of Lyell Immunopharma

Lyell Immunopharma operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Poseida Therapeutics, Juno Therapeutics, TScan Therapeutics, Hummingbird Bioscience and Autolus, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Developer of gene therapies for treating cancer and liver orphan disease by using gene editing technologies
domain founded_year HQ Location
CAR T-cell and T-cell receptor immunotherapies for cancer are developed.
domain founded_year HQ Location
T cell-based treatments for immunological and oncological disorders are developed.
domain founded_year HQ Location
Antibody drugs for cancer treatment are developed.
domain founded_year HQ Location
Engineered T-cell immunotherapies are developed for cancer and auto-immune diseases.
Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

Latest news on Lyell Immunopharma

Frequently Asked Questions about Lyell Immunopharma

When was Lyell Immunopharma founded?

Lyell Immunopharma was founded in 2018.

Where is Lyell Immunopharma located?

Lyell Immunopharma is headquartered in San Francisco, United States. It is registered at San Francisco, California, United States.

Who is the current CEO of Lyell Immunopharma?

Rick Klausner is the current CEO of Lyell Immunopharma. They have also founded this company.

Is Lyell Immunopharma a funded company?

Lyell Immunopharma is a funded company, having raised a total of $493M across 3 funding rounds to date.

How many employees does Lyell Immunopharma have?

As of Dec 31, 2024, the latest employee count at Lyell Immunopharma is 300.

What is the annual revenue of Lyell Immunopharma?

Annual revenue of Lyell Immunopharma is $61K as on Dec 31, 2024.

What does Lyell Immunopharma do?

Founded in 2018 and based in San Francisco, United States, the biotechnology firm focuses on oncology. CAR-T therapies are advanced for treating ROR1-positive non-small cell lung cancer and triple-negative breast cancer through the lead program LYL797. An autologous TIL therapy, LYL845, is pursued for multiple solid tumors. Operations center on clinical development of these immunotherapies to address unmet needs in cancer care.

Who are the top competitors of Lyell Immunopharma?

Lyell Immunopharma's top competitors include Hummingbird Bioscience, Juno Therapeutics and Immatics.

What products or services does Lyell Immunopharma offer?

Lyell Immunopharma offers LYL314 and CAR T-cell Therapies.

Is Lyell Immunopharma publicly traded?

Yes, Lyell Immunopharma is publicly traded on NASDAQ under the ticker symbol LYEL.

How many acquisitions has Lyell Immunopharma made?

Lyell Immunopharma has made 1 acquisition, including ImmPACT-Bio.

Who are Lyell Immunopharma's investors?

Lyell Immunopharma has 2 investors. Key investors include GSK, and Sahsen Ventures.

What is Lyell Immunopharma's ticker symbol?

The ticker symbol of Lyell Immunopharma is LYEL on NASDAQ.

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