Neon Therapeutics

Cambridge, United States Founded: 2015 • Age: 11 yrs Acquired By BioNTech
Tumor-specific neoantigens are identified for personalized cancer vaccine development.

About Neon Therapeutics

Neon Therapeutics is a Healthcare company based in Cambridge (United States) founded in 2015, and was acquired by BioNTech in January 2020. Tumor-specific neoantigens are identified for personalized cancer vaccine development. Neon Therapeutics has raised $161 million across 3 funding rounds from investors including Fidelity Investments, BioNTech and ArrowMark Partners. The company has 306 employees. The company was acqui-hired. Its focus areas include Life Sciences, Oncology, Drugs and Diversified. Its legal entity is NEON THERAPEUTICS, INC. Its competitors include C4 Therapeutics, Erasca and Revolution Medicines; 3 of its 3 listed competitors have raised funding.

Company details

Neon Therapeutics develops personalized vaccines and autologous T-cell therapies for cancer. It is based on research from the Dana Farber Cancer Institute, the Broad Institute and the Massachusetts General Hospital. The company has a proprietary platform for identifying targets through immune monitoring and epitope profiling. Their lead candidate, NEO-PV-01, is a personalized neoantigen vaccine for cancer that is being investigated for the treatment of melanoma, smoking associated NSCLC, and bladder cancer and is currently undergoing clinical development (Phase 1b trials) in combination with Opdivo. The company uses next-generation genomic sequencing, a proprietary computational pipeline (which identifies cancer mutations and determines which mutations are most likely to encode immunogenic neoantigens recognized on tumor cells) and an n1 manufacturing process to produce vaccines that specifically target individual patient tumors. In addition, Neon Therapeutics is also investigating targeted autologous T-cell therapies for other oncology investigations.

  • Headquarters Cambridge, United States
  • Employees 306
  • Stage Acquired
  • Sectors
    Healthcare
  • Website neontherapeutics.com
  • Social LinkedIn X
  • Acquired by BioNTech (Jan 2020)
  • Legal Name Neon Therapeutics, Inc.
Key Metrics
  • Net Profit
    -$79.78 M (USD)
    -4
    as on Dec 31, 2019
  • EBITDA
    -$81.14 M (USD)
    -3
    as on Dec 31, 2019
  • Total Equity Funding
    $161M (USD)

    in 3 rounds

  • Latest Funding Round
    $36M (USD), Series B

    Dec 2017

  • Investors
  • Employee Count
    306
  • Acquired by
    BioNTech

    (Jan 2020)

Funding Insights of Neon Therapeutics

Neon Therapeutics has successfully raised a total of $161M across 3 strategic funding rounds. The most recent funding activity was a Series B round of $36 million completed in December 2017. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $161M
  • Total Rounds 3
  • Last Round Series B β€” $36M
  • First Round $55M

    (Oct 2015)

  • Investors Count 12

All 3 funding rounds of Neon Therapeutics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Dec 2017$36MSeries B––
Jan 2017$70MSeries B–PFM Health Sciences
Oct 2015$55MSeries A–Access Industries, Clal Biotechnology Industries
–
Valuation history

13 investors in total: 13 institutional.

Investors in Neon Therapeutics

Neon Therapeutics has secured backing from 13 investors, including institutional and venture fund investors. Prominent investors backing the company include Fidelity Investments, BioNTech and ArrowMark Partners.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Investment and holding company controlled by Len Blavatnik
accessindustries.comNew York, United States
PE firm investing in the US
nextechinvest.comZurich, Switzerland
Global private equity investments are managed with long-term focus.
hillhouseinvestment.comNew York, United States
Investing in Life Sciences sectors like Healthcare and Biotechnology.
casdincapital.com
Healthcare companies are invested in by this private equity firm.
pfmhealthsciences.comSan Francisco, United States
Venture capital funding is provided to early-stage life science companies.
thirdrockventures.comBoston, United States
Early-stage life sciences investments are made globally by Inbio Ventures.
inbio-ventures.comMoscow, Russia
Life Sciences focused VC firm investing in Israel and the US
1993cbi.co.ilTel Aviv, Israel
Provider of brokerage accounts, retirement planning, wealth management, and trading platforms
1946fidelity.comBoston, United States
Diversified investment management services are provided to institutional clients.
wellington.comBoston, United States
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Investor details for Neon Therapeutics

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People of Neon Therapeutics

2 people are tracked at Neon Therapeutics (2 in leadership); the tracked headcount is 306.

NameRoleGroup
Hugh O’Dowd
CEOLeadership
Kelledy Manson
Vice President of Product DevelopmentLeadership
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Timeline of Neon Therapeutics

4 dated milestones of Neon Therapeutics across 5 years, from founding to its latest funding, stage changes and deals.

  1. Founded Neon Therapeutics is founded.
  2. Funding First funding round of $55.0M.
  3. Funding Latest funding round, Series B, of $36.0M.
  4. Exit Acquired by BioNTech.

Competitors of Neon Therapeutics

Neon Therapeutics has 3 listed competitors in our database, 3 of them funded. They include C4 Therapeutics, Erasca and Revolution Medicines.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
c4therapeutics.com2016Cambridge, United States$223M121
Small-molecule drugs for cancer treatment are developed via Degronimid platform.
erasca.com2018San Diego, United States$300M120
Small molecule therapeutics for cancer treatment are developed.
revmed.com2014Redwood, United States$326.29M181
Cancer therapies are developed using selective pathway inhibitors.
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Detailed competitors of Neon Therapeutics

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Top companies in Immunology & Cancer Therapeutics

3 companies that operate in the same segment as Neon Therapeutics (Immunology & Cancer Therapeutics) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Targeted and immune-oncology drugs for cancer treatment are developed.
2010Cambridge, Massachusetts, United StatesUSD 172 M
Immuno-modulatory therapies for dementia and neurodegenerative disorders are developed.
2013San Francisco, California, United StatesUSD 214.78 MUSD 21.05 M211
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Related news about Neon Therapeutics

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Frequently Asked Questions about Neon Therapeutics

Neon Therapeutics was founded in 2015.

Neon Therapeutics is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.

Neon Therapeutics is a funded company, having raised a total of $161M across 3 funding rounds to date. The company's 1st funding round was a Series A of $55M, raised on Oct 2015.

Neon Therapeutics has 306 employees.

Neon Therapeutics develops personalized vaccines and autologous T-cell therapies for cancer. It is based on research from the Dana Farber Cancer Institute, the Broad Institute and the Massachusetts General Hospital. The company has a proprietary platform for identifying targets through immune monitoring and epitope profiling. Their lead candidate, NEO-PV-01, is a personalized neoantigen vaccine for cancer that is being investigated for the treatment of melanoma, smoking associated NSCLC, and bladder cancer and is currently undergoing clinical development (Phase 1b trials) in combination with Opdivo. The company uses next-generation genomic sequencing, a proprietary computational pipeline (which identifies cancer mutations and determines which mutations are most likely to encode immunogenic neoantigens recognized on tumor cells) and an n1 manufacturing process to produce vaccines that specifically target individual patient tumors. In addition, Neon Therapeutics is also investigating targeted autologous T-cell therapies for other oncology investigations.

Neon Therapeutics's top competitors include C4 Therapeutics, Erasca and Revolution Medicines.

Neon Therapeutics has 13 investors. Key investors include Fidelity Investments, BioNTech, ArrowMark Partners, Clal Biotechnology Industries, and Access Industries.

Neon Therapeutics operates through Neon Therapeutics, Inc..

Yes. Neon Therapeutics was acquired by BioNTech in January 2020.

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