Nested Knowledge

Saint Paul, United States Founded: 2018 • Age: 8 yrs
Clinical evidence platform provided for pharma, device, and research entities.
Annual revenue - Latest available
Total funding $6.8M 7 rounds
Employees - Tracked headcount
Investors 1 Known backers
Products - Services tracked
Competitors 9 Brand Intelligence

About Nested Knowledge

Nested Knowledge is a company based in Saint Paul (United States) founded in 2018 by Stephen Mead, Karl Holub, Keith Kallmes, and Kevin Kallmes. Nested Knowledge has raised $6.76 million across 7 funding rounds from investors including HHS. Nested Knowledge operates in a competitive market with competitors including OpenEvidence, Copient Health, iDoctus, The Clinics and Ciplamed, among others.

  • Headquarter Saint Paul, United States
  • Founders Stephen Mead, Karl Holub, Keith Kallmes, Kevin Kallmes
  • Sectors
    Healthcare
  • Email
    ***********
  • Phone
    *********
  • Website
    *********
  • Social
    *********
Operational Areas
Healthcare → Health Technology & Digital Health
Key Metrics
  • Annual Revenue
  • Net Profit
  • EBITDA
  • Total Equity Funding
    $6.76 M (USD)

    in 7 rounds

  • Latest Funding Round
    $4.18 M (USD), Series A

    Dec 31, 2025

  • Investors
  • Employee Count
    Employee Count
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People of Nested Knowledge

Headcount 10-50
Employee Profiles 9
Board Members and Advisors 4
Employee Profiles
People
Karl Holub
CTO, Co-founder
People
Kevin Kallmes
CEO, Co-Founder
People
Stephen Mead
Chief Software Engineer, Co-founder
People
Marius Sauca
Director, Business Development for Europe

Unlock access to complete

Board Members and Advisors
people
Julia Brodsky
Advisor
people
Dheerendra Kommala
Advisor
people
Tony Coniglio
Advisor

Unlock access to complete

Funding Insights of Nested Knowledge

Nested Knowledge has successfully raised a total of $6.76M across 7 strategic funding rounds. The most recent funding activity was a Series A round of $4.18 million completed in December 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 7
  • Last Round Series A — $4.2M
  • First Round

    (18 Mar 2019)

  • Investors Count 1
Date Amount Transaction Name Valuation Lead Investors Investors
Dec, 2025 Amount Series A - Nested Knowledge Valuation

investors

Sep, 2024 Amount Grant - Nested Knowledge Valuation

investors

HHS
Dec, 2023 Amount Seed - Nested Knowledge Valuation

investors

Investors in Nested Knowledge

Nested Knowledge has secured backing from 1 investor, including institutional investors. Prominent investors backing the company include HHS.

All
Institutional
Investor Description Founded Year Domain Location
Public health and human services are overseen by HHS.
Founded Year Domain Location

Investments & Acquisitions by Nested Knowledge

Investments

Financial Statements - Nested Knowledge

Nested Knowledge Comparisons

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Competitors of Nested Knowledge

Nested Knowledge operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as OpenEvidence, Copient Health, iDoctus, The Clinics and Ciplamed, among others.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Medical evidence is aggregated and visualized for healthcare professionals.
domain founded_year HQ Location
Predictive analysis solutions are provided for healthcare providers.
domain founded_year HQ Location
Medical app providing drug searches, interactions, and clinical tools for healthcare professionals.
domain founded_year HQ Location
App offering clinical resources
domain founded_year HQ Location
Offers online medical news, guidelines, and educational content for professionals.

Latest news on Nested Knowledge

Frequently Asked Questions about Nested Knowledge

Nested Knowledge was founded in 2018 and raised its 1st funding round 1 year after it was founded.

Nested Knowledge is headquartered in Saint Paul, United States. It is registered at Saint Paul, Minnesota, United States.

Kevin Kallmes is the current CEO of Nested Knowledge. They have also founded this company.

Nested Knowledge is a funded company, having raised a total of $6.76M across 7 funding rounds to date. The company's 1st funding round was a Seed of $1M, raised on Mar 18, 2019.

Provider of a clinical evidence platform for pharma, device, and research entities. The company offers a digital platform that helps both clinicians and corporate researchers to optimize their meta-analytical research process in a modernized visualization tool for comparing patient characteristics, treatment plans, and therapy outcomes. They offer individual and institutional subscriptions to use the platform to build and present living reviews as well as employing proprietary AI technologies to enhance the research process.

Nested Knowledge's top competitors include OpenEvidence, QxMD and Emerson Ecologics.

Nested Knowledge has 1 investor. Key investors include HHS.

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