Nuclein

Austin, United States Founded: 2017 • Age: 9 yrs
Handheld PCR devices for infectious disease detection are developed.

About Nuclein

Nuclein is a Healthcare company based in Austin (United States) founded in 2017. Handheld PCR devices for infectious disease detection are developed. Nuclein has raised $30.09 million across 7 funding rounds from investors including Trinity Investors. Nuclein offers products and services including DASH Rapid PCR System and DASH SARS-CoV-2 & Flu A/B Test. Its focus areas include Life Sciences, Infectious Diseases, Medical Devices and Screening. Its legal entity is Nuclein, LLC. Its competitors include CellScope, Orphidia and Mel-Mont Medical; 2 of its 3 listed competitors have raised funding.

Company details

Nuclein was founded in 2017 in Austin, United States, and operates in the medical diagnostics sector. A handheld PCR device named NUCLEIN is developed, utilizing standard real-time PCR technology. No technical expertise is required for operation, and the battery-powered unit delivers results within one hour. Applications include diagnosis of COVID-19 and other infectious diseases in field settings.

Operational Areas
Key Metrics
  • Total Equity Funding
    $30.09M (USD)

    in 7 rounds

  • Latest Funding Round
    $11.11M (USD), Series B

    Jul 2026

  • Investors

Products & Services of Nuclein

Nuclein offers a comprehensive portfolio of products and services, including DASH Rapid PCR System and DASH SARS-CoV-2 & Flu A/B Test.

DASH Rapid PCR System
Diagnostic Device

Delivers lab-quality PCR results in 15 minutes for point-of-care use.

DASH SARS-CoV-2 & Flu A/B Test
Test Kit

Enables detection of SARS-CoV-2 and influenza viruses via PCR.

Funding Insights of Nuclein

Nuclein has successfully raised a total of $30.09M across 7 strategic funding rounds. The most recent funding activity was a Series B round of $11.11 million completed in July 2026. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $30.09M
  • Total Rounds 7
  • Last Round Series B โ€” $11.11M
  • First Round $14M

    (Mar 2021)

  • Investors Count 1

All 7 funding rounds of Nuclein with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Jul 2026$11.11MSeries Bโ€“โ€“
โ€“
Jun 2026$1.3MDebt – Conventionalโ€“โ€“
โ€“
Jul 2025$9.78MDebt – Conventionalโ€“โ€“
โ€“
Jan 2025$750,000Series Bโ€“โ€“
โ€“
Dec 2023$8.79MDebt – Conventionalโ€“โ€“
โ€“
Mar 2023$4.22MSeries Bโ€“โ€“
โ€“
Mar 2021$14MSeries Bโ€“Trinity Investors
โ€“
Valuation history

1 investors in total: 1 institutional.

Investors in Nuclein

Nuclein has secured backing from 1 investor, including venture fund investors. Prominent investors backing the company include Trinity Investors.

All
Venture Fund
InvestorDescriptionFounded YearDomainLocation
trinityinvestors.com
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Investor details for Nuclein

The complete investor list, round-by-round participation and investor portfolios require an active premium plan.

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People of Nuclein

13 people are tracked at Nuclein (8 in leadership, 5 in team).

NameRoleGroup
Mark Hunter
Vice President, OperationsLeadership
Jeffrey Stukuls
CFOLeadership
Alan Blake
Chief Executive OfficerLeadership
Huiping Zhu
Vice President, Assay DevelopmentLeadership
Michael Karberg
Chief ScientistLeadership
Brian Estes, GPHR, PHR
Chief People OfficerLeadership
Reid Sadler
Chief Commercial Officer (cco)Leadership
Miranda Chavez
Director Of Program ManagementLeadership
Skyler Cadenhead
Product Development ManagerTeam
Jeannie Phipps
ControllerTeam
Ryan Cho
Senior Software Quality EngineerTeam
Grant Kuempel
Senior Systems Integration EngineerTeam
Johnathan Kwong, CQE, CQA
Quality Systems ManagerTeam
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Complete people profiles for Nuclein

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Timeline of Nuclein

3 dated milestones of Nuclein across 9 years, from founding to its latest funding, stage changes and deals.

  1. Founded Nuclein is founded.
  2. Funding First funding round of $14.0M.
  3. Funding Latest funding round, Series B, of $11.1M.

Competitors of Nuclein

Nuclein has 3 listed competitors in our database, 2 of them funded. They include CellScope, Orphidia and Mel-Mont Medical.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
cellscope.com2010San Francisco, United States$4.62M
In-ear visibility is enabled by smartphone-attached otoscope for at-home diagnosis.
orphidia.com2013San Francisco, United States
Handheld device for point-of-care chronic disease diagnostics is developed.
mel-montmedical.com2014Doral, United States$3M
Molecular screening devices for early infectious disease detection are developed.
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Detailed competitors of Nuclein

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Web traffic of Nuclein

The website of Nuclein (nuclein.com) receives about 1.9K visits a month.

  • Monthly visits
    1.9K

    ▼ 39.7% vs previous month

Top companies in Infectious Diseases

3 companies that operate in the same segment as Nuclein (Infectious Diseases) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Developer of molecular diagnostic testing solutions
1996Sunnyvale, California, United StatesUSD 19.1 MUSD 54.88 M208
Therapeutics for drug-resistant bacterial infections are developed.
2013Cambridge, Massachusetts, United StatesUSD 114.7 MUSD 59.62 M32
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Related news about Nuclein

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Frequently Asked Questions about Nuclein

Nuclein was founded in 2017 and raised its 1st funding round 4 years after it was founded.

Nuclein is headquartered in Austin, United States. It is registered at Austin, Texas, United States.

Nuclein is a funded company, having raised a total of $30.09M across 7 funding rounds to date. The company's 1st funding round was a Series B of $14M, raised on Mar 2021.

Nuclein was founded in 2017 in Austin, United States, and operates in the medical diagnostics sector. A handheld PCR device named NUCLEIN is developed, utilizing standard real-time PCR technology. No technical expertise is required for operation, and the battery-powered unit delivers results within one hour. Applications include diagnosis of COVID-19 and other infectious diseases in field settings.

Nuclein's top competitors include CellScope, Mel-Mont Medical and Orphidia.

Nuclein offers DASH Rapid PCR System and DASH SARS-CoV-2 & Flu A/B Test.

Nuclein has 1 investor. Key investors include Trinity Investors.

Nuclein operates through Nuclein, Llc.

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