Orna

Cambridge, United States Founded: 2020 • Age: 6 yrs
Technologies for producing circular RNA therapeutics are developed.
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About Orna

Orna is a company based in Cambridge (United States) founded in 2020 by Alexander Wesselhoeft.. Orna has raised $201 million across 2 funding rounds from investors including Novartis, Merck and Kite Pharma. The company has 113 employees as of December 31, 2022. Orna has completed 1 acquisition, including ReNAgade. Orna offers products and services including oRNA, panCAR, and LNP Delivery. Orna operates in a competitive market with competitors including Dicerna Pharmaceuticals, OliX Pharmaceuticals, Envisagenics, Rznomics and Arcturus Therapeutics, among others.

  • Headquarter Cambridge, United States
  • Employees 113 as on 31 Dec, 2022
  • Founders Alexander Wesselhoeft
  • Sectors
    Healthcare
  • Email
    ***********
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Orna Therapeutics, Inc.
Operational Areas
Healthcare → Biotechnology, Genomics & Life Sciences Research
Key Metrics
  • Annual Revenue
  • Net Profit
  • EBITDA
  • Total Equity Funding
    $201 M (USD)

    in 2 rounds

  • Latest Funding Round
    $121 M (USD), Series B

    Aug 14, 2022

  • Investors
    Novartis

    & 9 more

  • Employee Count
    113

    as on Dec 31, 2022

  • Investments & Acquisitions
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Products & Services of Orna

Orna offers a comprehensive portfolio of products and services, including oRNA, panCAR, and LNP Delivery. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.

Primary

Engineered circular RNA for enhanced protein expression in disease treatment.

In vivo system for cancer cell therapy without preconditioning.

Lipid nanoparticles for targeted RNA delivery beyond the liver.

People of Orna
Headcount 10-50
Employee Profiles 24
Board Members and Advisors 5
Employee Profiles
People
William Shen
Chief Business Officer
People
Omer A. Chaudhry
Scientist, CMC
People
Thomas M. Barnes
CEO
People
Liz Molano
Head Of People And Culture

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Board Members and Advisors
people
Morana Jovan-Embiricos
Director
people
Daniel Anderson
Director
people
Brian Goodman
Director
people
Ansbert Gadicke
Chairman

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Funding Insights of Orna

Orna has successfully raised a total of $201M across 2 strategic funding rounds. The most recent funding activity was a Series B round of $121 million completed in August 2022. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 2
  • Last Round Series B — $121.0M
  • First Round

    (24 Feb 2021)

  • Investors Count 10
Date Amount Transaction Name Valuation Lead Investors Investors
Aug, 2022 Amount Series B - Orna Valuation Merck
Feb, 2021 Amount Series A - Orna Valuation MPM Capital , Taiho Ventures
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Investors in Orna

Orna has secured backing from 10 investors, including institutional and venture fund investors. Prominent investors backing the company include Novartis, Merck and Kite Pharma. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Investor Description Founded Year Domain Location
-
Founded Year Domain Location
Taiho Ventures is focused on investing in global biotech ventures.
Founded Year Domain Location
-
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by Orna

Orna has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include ReNAgade. These strategic investments and acquisitions demonstrate the company's commitment to growth through portfolio expansion, market consolidation, technology integration, and strategic partnerships that enhance competitive positioning and drive long-term value creation.

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Acquisitions
Company Name Description Domain Location Founded Year Amount
RNA-based medicines are developed for treating multiple diseases.
2021
Company Name Description Domain Location Founded Year Amount
OVO is recognized as a smart digital payment application.
2017
Bionic investment advisor platform
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014

Financial Statements - Orna

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Orna Comparisons

Employees
+
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Competitors of Orna

Orna operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Dicerna Pharmaceuticals, OliX Pharmaceuticals, Envisagenics, Rznomics and Arcturus Therapeutics, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Drugs are developed using RNA interference technology platform.
domain founded_year HQ Location
RNAi therapeutics are developed for dermal, ophthalmic, and pulmonary diseases.
domain founded_year HQ Location
RNA splicing therapeutics are discovered and developed through AI-driven biotechnology.
domain founded_year HQ Location
Developer of drugs for anti-cancer and refractory diseases based on RNA Platform technology
domain founded_year HQ Location
RNAi technologies are developed for treating rare orphan diseases.
Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

Frequently Asked Questions about Orna

When was Orna founded?

Orna was founded in 2020 and raised its 1st funding round 1 year after it was founded.

Where is Orna located?

Orna is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.

Who is the current CEO of Orna?

Tom Barnes is the current CEO of Orna.

Is Orna a funded company?

Orna is a funded company, having raised a total of $201M across 2 funding rounds to date. The company's 1st funding round was a Series A of $80M, raised on Feb 24, 2021.

How many employees does Orna have?

As of Dec 31, 2022, the latest employee count at Orna is 113.

What does Orna do?

Orna was founded in 2020 in Cambridge, United States, within the biotechnology sector focused on RNA therapeutics. Purification methods, IRES technology for protein expression, and lipid nanoparticle formulations are developed by the company. RNA viruses and enzymes are utilized to enable production, delivery, and gene expression in the human body. Therapeutics targeting cancer, autoimmune diseases, regenerative medicine, and genetic disorders are being advanced.

Who are the top competitors of Orna?
What products or services does Orna offer?

Orna offers oRNA, panCAR, and LNP Delivery.

How many acquisitions has Orna made?

Orna has made 1 acquisition, including ReNAgade.

Who are Orna's investors?

Orna has 10 investors. Key investors include Novartis, Merck, Kite Pharma, Bristol-Myers Squibb, and Turmeric Acquisition Corp.

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