About PainReform
PainReform is a company based in Herzliya (Israel) founded in 2007. It operates as a HealthTech. PainReform has raised $12 million across 4 funding rounds from investors including LayerBio. The company has 6 employees as of December 31, 2024. PainReform has completed 1 acquisition, including LayerBio. PainReform offers products and services including PRF-110. PainReform operates in a competitive market with competitors including Flexion Therapeutics, Eliem Therapeutics, Zogenix, Heron Therapeutics and Ethypharm, among others.
- Headquarter Herzliya, Israel
- Employees 6 as on 31 Dec, 2024
- Stage Public
-
Sectors
Healthcare
-
Email
***********
-
Phone
*********
-
Website
*********
-
Social
*********
- Legal Name Painreform Ltd.
-
Annual Revenue
$00as on Dec 31, 2024
-
Net Profit
$-14.59 M-56.12as on Dec 31, 2024
-
EBITDA
$-14.66 M-53.17as on Dec 31, 2024
-
Total Equity Funding
$12 M (USD)
in 4 rounds
-
Latest Funding Round
$600 K (USD), Post-IPO
Jul 10, 2025
- Investors
-
Employee Count
6
as on Dec 31, 2024
- Investments & Acquisitions
Unlock complete access to The Company Check
Get unrestricted viewing across everything we track — from companies and brands to investors, funding rounds, acquisitions, financials, and more.
- Unlimited viewing on all profiles Companies, investors, financials, funding, acquisitions & directors
- Full access to every database India & global coverage, advanced filters and rich profile details
- Always-on access from your team account Single premium plan for everything you see on the portal
IPO & Listings of PainReform
PainReform is a publicly listed company on the NASDAQ with ticker symbol PRFX in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.
Products & Services of PainReform
PainReform offers a comprehensive portfolio of products and services, including PRF-110. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.
A viscous solution for post-surgical pain relief.
Unlock access to complete
Unlock access to complete
Unlock access to complete
Funding Insights of PainReform
PainReform has successfully raised a total of $12M across 4 strategic funding rounds. The most recent funding activity was a Post-IPO round of $600 thousand completed in July 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.
- Total Funding Total Funding
- Total Rounds 4
- Last Round Post-IPO — $600,000
-
First Round
First Round
(10 Jul 2018)
- Investors Count 1
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jul, 2025 | Amount | Post-IPO - PainReform | Valuation |
investors |
|
| Jul, 2025 | Amount | Post-IPO - PainReform | Valuation |
investors |
|
| Mar, 2021 | Amount | Post-IPO - PainReform | Valuation |
investors |
|
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
|
| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
|
| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
|
| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
Investors in PainReform
PainReform has secured backing from 1 investor. Prominent investors backing the company include LayerBio. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.
| Investor | Description | Founded Year | Domain | Location |
|---|---|---|---|---|
|
Drug delivery solutions are developed for ophthalmology and wound care.
|
Founded Year | Domain | Location |
| Investor | Description | Founded Year | Domain | Location |
|---|---|---|---|---|
|
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
|
Founded Year | Domain | Location | |
|
Startup ecosystems are ignited through strategic investments by Signite Partners.
|
Founded Year | Domain | Location | |
|
Venture capital is directed toward companies in multiple sectors.
|
Founded Year | Domain | Location | |
|
Venture capital is invested in cybersecurity, fintech, and AI startups.
|
Founded Year | Domain | Location |
Investments & Acquisitions by PainReform
PainReform has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include LayerBio. These strategic investments and acquisitions demonstrate the company's commitment to growth through portfolio expansion, market consolidation, technology integration, and strategic partnerships that enhance competitive positioning and drive long-term value creation.
| Company Name | Description | Domain | Location | Founded Year | Amount |
|---|---|---|---|---|---|
|
Bionic investment advisor platform
|
2016 | ||||
|
Fine Asian gourmet food is offered by an internet-first restaurant.
|
2016 | ||||
|
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
|
2014 | ||||
|
Fine Asian gourmet food is offered by an internet-first restaurant.
|
2016 |
| Company Name | Description | Domain | Location | Founded Year | Amount |
|---|---|---|---|---|---|
|
Drug delivery solutions are developed for ophthalmology and wound care.
|
2013 |
| Company Name | Description | Domain | Location | Founded Year | Amount |
|---|---|---|---|---|---|
|
OVO is recognized as a smart digital payment application.
|
2017 | ||||
|
Bionic investment advisor platform
|
2016 | ||||
|
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
|
2014 | ||||
|
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
|
2014 |
Financial Statements - PainReform
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
|
| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
|
| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
|
| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
Painreform Comparisons
Competitors of PainReform
PainReform operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Flexion Therapeutics, Eliem Therapeutics, Zogenix, Heron Therapeutics and Ethypharm, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.
| Company Name | Domain | Founded year | HQ Location | Description |
|---|---|---|---|---|
| domain | founded_year | HQ Location |
Developer of therapies for the treatment of musculoskeletal disorders
|
|
| domain | founded_year | HQ Location |
Develops antibody-based treatments for autoimmune and inflammatory disorders.
|
|
| domain | founded_year | HQ Location |
Drug delivery systems for CNS disorders and pain are developed.
|
|
| domain | founded_year | HQ Location |
Reformulated injectables for chemotherapy side effects and pain are developed.
|
|
| domain | founded_year | HQ Location |
Therapies for pain and addiction treatment are developed.
|
| Company Name | Domain | Founded year | HQ Location | Description |
|---|---|---|---|---|
| domain | founded_year | HQ Location |
Multiple services are booked via an app-based platform.
|
|
| domain | founded_year | HQ Location |
On-demand services are booked through an app-based platform.
|
|
| domain | founded_year | HQ Location |
App based platform offering on demand delivery and ride-hailing services
|
|
| domain | founded_year | HQ Location |
Operates an on-demand hyperlocal delivery app for food and groceries.
|
Latest news on Painreform
Frequently Asked Questions about PainReform
When was PainReform founded?
PainReform was founded in 2007 and raised its 1st funding round 11 years after it was founded.
Where is PainReform located?
PainReform is headquartered in Herzliya, Israel. It is registered at Herzliya, Central District, Israel.
Is PainReform a funded company?
PainReform is a funded company, having raised a total of $12M across 4 funding rounds to date. The company's 1st funding round was a Post-IPO of $6M, raised on Jul 10, 2018.
How many employees does PainReform have?
As of Dec 31, 2024, the latest employee count at PainReform is 6.
What does PainReform do?
PainReform is a clinical-stage specialty pharmaceutical company engaged in the reformulation of established therapeutics. An extended-release drug-delivery system is developed to provide prolonged post-surgical pain relief, minimizing the need for repeated doses and reducing reliance on opiates. The primary product, PRF-110, is a viscous oil-based solution instilled into surgical wounds for localized analgesia. The company operates in the healthcare sector, targeting pain management solutions with innovative technologies to enhance efficacy and patient comfort while reducing adverse effects.
Who are the top competitors of PainReform?
PainReform's top competitors include Flexion Therapeutics, Cara Therapeutics and Satsuma Pharmaceuticals.
What products or services does PainReform offer?
PainReform offers PRF-110.
Is PainReform publicly traded?
Yes, PainReform is publicly traded on NASDAQ under the ticker symbol PRFX.
How many acquisitions has PainReform made?
PainReform has made 1 acquisition, including LayerBio.
Who are PainReform's investors?
PainReform has 1 investor. Key investors include LayerBio.
What is PainReform's ticker symbol?
The ticker symbol of PainReform is PRFX on NASDAQ.