About Plexium
Plexium is a company based in San Diego (United States) founded in 2017 by Andrew MacConnell.. Plexium has raised $225.12 million across 5 funding rounds from investors including Citadel, RA Capital and SoftBank Vision Fund. The company has 81 employees as of December 31, 2021. Plexium offers products and services including TPD Platform, Monovalent Degraders, and Molecular Glues. Plexium operates in a competitive market with competitors including Accutar Biotechnology, Lycia Therapeutics, Vicinitas, Photys Therapeutics and Uvic Steratics, among others.
- Headquarter San Diego, United States
- Employees 81 as on 31 Dec, 2021
- Founders Andrew MacConnell
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Sectors
Healthcare
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Phone
*********
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Website
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Social
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- Legal Name Plexium, Inc.
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Annual Revenue
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Net Profit
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EBITDA
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Total Equity Funding
$225.12 M (USD)
in 5 rounds
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Latest Funding Round
$60.12 M (USD), Series B
Jul 14, 2025
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Investors
Citadel
& 12 more
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Employee Count
81
as on Dec 31, 2021
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Products & Services of Plexium
Plexium offers a comprehensive portfolio of products and services, including TPD Platform, Monovalent Degraders, and Molecular Glues. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.
Platform for discovering targeted protein degrader therapeutics
Drugs designed for rational protein degradation applications
Compounds that facilitate targeted protein interactions
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Funding Insights of Plexium
Plexium has successfully raised a total of $225.12M across 5 strategic funding rounds. The most recent funding activity was a Series B round of $60.12 million completed in July 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.
- Total Funding Total Funding
- Total Rounds 5
- Last Round Series B — $60.1M
- First Round First Round
- Investors Count 13
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jul, 2025 | Amount | Series B - Plexium | Valuation |
investors |
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| Feb, 2022 | Amount | Series B - Plexium | Valuation | TCG Crossover , BVF Partners | |
| Jan, 2021 | Amount | Series A - Plexium | Valuation | Lux Capital , Pivotal bioVenture Partners |
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
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| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
Investors in Plexium
Plexium has secured backing from 13 investors, including institutional and venture fund investors. Prominent investors backing the company include Citadel, RA Capital and SoftBank Vision Fund. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.
| Investor | Description | Founded Year | Domain | Location |
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Founded Year | Domain | Location | |
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US private equity investments are managed by BVF Partners.
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Founded Year | Domain | Location | |
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VC firm focusing on life science sector
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Founded Year | Domain | Location |
| Investor | Description | Founded Year | Domain | Location |
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Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
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Founded Year | Domain | Location | |
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Startup ecosystems are ignited through strategic investments by Signite Partners.
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Founded Year | Domain | Location | |
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Venture capital is directed toward companies in multiple sectors.
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Founded Year | Domain | Location | |
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Venture capital is invested in cybersecurity, fintech, and AI startups.
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Founded Year | Domain | Location |
Investments & Acquisitions by Plexium
| Company Name | Description | Domain | Location | Founded Year | Amount |
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Bionic investment advisor platform
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2016 | ||||
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Fine Asian gourmet food is offered by an internet-first restaurant.
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2016 | ||||
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Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
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2014 | ||||
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Fine Asian gourmet food is offered by an internet-first restaurant.
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2016 |
Financial Statements - Plexium
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
Plexium Comparisons
Competitors of Plexium
Plexium operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Accutar Biotechnology, Lycia Therapeutics, Vicinitas, Photys Therapeutics and Uvic Steratics, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.
| Company Name | Domain | Founded year | HQ Location | Description |
|---|---|---|---|---|
| domain | founded_year | HQ Location |
AI-assisted tools for drug discovery are developed.
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| domain | founded_year | HQ Location |
Protein degradation drugs are developed for cancer and autoimmune diseases.
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| domain | founded_year | HQ Location |
Developer of therapeutics for cancer and genetic disorders
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| domain | founded_year | HQ Location |
Protein-based small molecules are developed to treat human diseases.
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| domain | founded_year | HQ Location |
Anti-cancer drugs are developed via Proteolysis Targeting Chimera technology.
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| Company Name | Domain | Founded year | HQ Location | Description |
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| domain | founded_year | HQ Location |
Multiple services are booked via an app-based platform.
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| domain | founded_year | HQ Location |
On-demand services are booked through an app-based platform.
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| domain | founded_year | HQ Location |
App based platform offering on demand delivery and ride-hailing services
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| domain | founded_year | HQ Location |
Operates an on-demand hyperlocal delivery app for food and groceries.
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Latest news on Plexium
Frequently Asked Questions about Plexium
When was Plexium founded?
Plexium was founded in 2017 and raised its 1st funding round 1 year after it was founded.
Where is Plexium located?
Plexium is headquartered in San Diego, United States. It is registered at San Diego, California, United States.
Is Plexium a funded company?
Plexium is a funded company, having raised a total of $225.12M across 5 funding rounds to date. The company's 1st funding round was a Series A of $35M, raised on Feb 01, 2018.
How many employees does Plexium have?
As of Dec 31, 2021, the latest employee count at Plexium is 81.
What does Plexium do?
Plexium offers integrated chemistry services. They provide synthetic organic chemistry, analytical chemistry, spectroscopy, combinatorial chemistry, and others.
Who are the top competitors of Plexium?
Plexium's top competitors include Photys Therapeutics, Uvic Steratics and Accutar Biotechnology.
What products or services does Plexium offer?
Plexium offers TPD Platform, Monovalent Degraders, and Molecular Glues.
Who are Plexium's investors?
Plexium has 13 investors. Key investors include Citadel, RA Capital, SoftBank Vision Fund, The Column Group, and TCG Crossover.