Prelude Therapeutics

Philadelphia, United States Founded: 2016 • Age: 10 yrs
Chromatin-targeting drugs are developed for cancer and rare diseases.
Annual revenue $7.0M Latest available
Total funding $145.0M 4 rounds
Employees 131 Tracked headcount
Investors 2 Known backers
Products 4 Services tracked
Competitors 10 Brand Intelligence

About Prelude Therapeutics

Prelude Therapeutics is a company based in Philadelphia (United States) founded in 2016 by Kris Vaddi. It operates as a HealthTech. Prelude Therapeutics has raised $145 million across 4 funding rounds from investors including Fidelity Investments and Orbimed. The company has 131 employees as of December 31, 2024. Prelude Therapeutics offers products and services including SMARCA2 Degraders, KAT6A Degraders, Precision ADCs, and CDK Inhibitors. Prelude Therapeutics operates in a competitive market with competitors including Jazz Pharmaceuticals, Revolution Medicines, Blueprint Medicines, Syndax and C4 Therapeutics, among others.

  • Headquarter Philadelphia, United States
  • Employees 131 as on 31 Dec, 2024
  • Founders Kris Vaddi
  • Stage Public
  • Sectors
    Healthcare
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  • Legal Name Prelude Therapeutics Incorporated
Operational Areas
Healthcare → Healthcare Products & Supplies Unlock Sub-Sector Unlock Segment
Key Metrics
  • Annual Revenue
    $7 M (USD)
    0
    as on Dec 31, 2024
  • Net Profit
    -$127.17 M (USD)
    -4.38
    as on Dec 31, 2024
  • EBITDA
    -$137.94 M (USD)
    -5.21
    as on Dec 31, 2024
  • Total Equity Funding
    $145 M (USD)

    in 4 rounds

  • Latest Funding Round
    $50 M (USD), Series C

    Aug 24, 2020

  • Investors
  • Employee Count
    131

    as on Dec 31, 2024

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IPO & Listings of Prelude Therapeutics

Prelude Therapeutics is a publicly listed company on the NASDAQ with ticker symbol PRLD in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

Exchange: NASDAQ · Ticker: PRLD · Sector: Health technology · USA

Products & Services of Prelude Therapeutics

Prelude Therapeutics offers a comprehensive portfolio of products and services, including SMARCA2 Degraders, KAT6A Degraders, Precision ADCs, and CDK Inhibitors.

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Primary

SMARCA2 degraders are developed for cancer treatment efficacy.

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KAT6A degraders are designed for breast cancer treatment.

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Precision ADCs are created for targeted cancer therapy.

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CDK inhibitors are formulated for various cancer treatments.

People of Prelude Therapeutics

Headcount 50-200
Employee Profiles 45
Board Members and Advisors 5
Employee Profiles
People
Jane Huang
President & Chief Medical Officer
People
Bill Novotny
SVP of Clinical Development
People
Aimee Crombie
SVP & Head of Strategic Planning & Operations
People
Michele Porreca
Chief People Officer

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Funding Insights of Prelude Therapeutics

Prelude Therapeutics has successfully raised a total of $145M across 4 strategic funding rounds. The most recent funding activity was a Series C round of $50 million completed in August 2020. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

Investors in Prelude Therapeutics

Prelude Therapeutics has secured backing from 2 investors, including venture fund and institutional investors. Prominent investors backing the company include Fidelity Investments and Orbimed.

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Venture Fund
Institutional
Investor Description Founded Year Domain Location
Investments are made by OrbiMed in global healthcare innovations across biopharmaceuticals and related fields.
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Provider of brokerage accounts, retirement planning, wealth management, and trading platforms
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Investor details for Prelude Therapeutics

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Investments & Acquisitions by Prelude Therapeutics

Investments
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Investment portfolio details for Prelude Therapeutics

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Financial Statements - Prelude Therapeutics

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Detailed financials for Prelude Therapeutics

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Prelude Therapeutics Comparisons

Prelude Therapeutics Primary company
Description
Chromatin-targeting drugs are developed for cancer and rare ...
Location
Philadelphia, United States
Founded Year
2016
Annual Revenue
$7 M (USD)
Net Profit
-$127.17 M (USD)
EBITDA
-$137.94 M (USD)
Employees
131
As of 2024
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Peer comparison for Prelude Therapeutics

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Competitors of Prelude Therapeutics

Prelude Therapeutics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Jazz Pharmaceuticals, Revolution Medicines, Blueprint Medicines, Syndax and C4 Therapeutics, among others.

Company Name Domain Founded year HQ Location Description
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Novel biopharmaceutical medicines are developed for unmet medical needs.
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Cancer therapies are developed using selective pathway inhibitors.
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Selective kinase inhibitors are developed for genomically defined cancers.
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Targeted therapies for cancer treatment are developed.
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Small-molecule drugs for cancer treatment are developed via Degronimid platform.
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Small molecule therapeutics for cancer treatment are developed.
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Detailed competitors of Prelude Therapeutics

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Latest news on Prelude Therapeutics

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Complete news archive for Prelude Therapeutics

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Frequently Asked Questions about Prelude Therapeutics

Prelude Therapeutics was founded in 2016.

Prelude Therapeutics is headquartered in Philadelphia, United States. It is registered at Philadelphia, Pennsylvania, United States.

Kris Vaddi is the current CEO of Prelude Therapeutics. They have also founded this company.

Prelude Therapeutics is a funded company, having raised a total of $145M across 4 funding rounds to date.

As of Dec 31, 2024, the latest employee count at Prelude Therapeutics is 131.

Annual revenue of Prelude Therapeutics is $7M as on Dec 31, 2024.

Prelude Therapeutics is engaged in the discovery and development of innovative cancer medicines. The company specializes in precision oncology, targeting high unmet needs with novel drug candidates. Programs include first-in-class SMARCA2 and KAT6A degraders, alongside precision antibody-drug conjugates (ADCs). Their expertise in targeted protein degradation is leveraged to advance next-generation therapies. Collaborations with partners like AbCellera enhance their ADC development. The focus remains on extending precision medicine benefits to cancer patients across various tumor types and resistance mechanisms.

Prelude Therapeutics's top competitors include Jazz Pharmaceuticals, C4 Therapeutics and argenx.

Prelude Therapeutics offers SMARCA2 Degraders, KAT6A Degraders, Precision ADCs, and CDK Inhibitors.

Yes, Prelude Therapeutics is publicly traded on NASDAQ under the ticker symbol PRLD.

Prelude Therapeutics has 2 investors. Key investors include Fidelity Investments, and Orbimed.

The ticker symbol of Prelude Therapeutics is PRLD on NASDAQ.

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