Prelude Therapeutics

Philadelphia, United States Founded: 2016 • Age: 10 yrs
Chromatin-targeting drugs are developed for cancer and rare diseases.
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About Prelude Therapeutics

Prelude Therapeutics is a company based in Philadelphia (United States) founded in 2016 by Kris Vaddi. It operates as a HealthTech. Prelude Therapeutics has raised $145 million across 4 funding rounds from investors including Fidelity Investments and Orbimed. The company has 131 employees as of December 31, 2024. Prelude Therapeutics offers products and services including SMARCA2 Degraders, KAT6A Degraders, Precision ADCs, and CDK Inhibitors. Prelude Therapeutics operates in a competitive market with competitors including Jazz Pharmaceuticals, Revolution Medicines, Blueprint Medicines, Syndax and C4 Therapeutics, among others.

  • Headquarter Philadelphia, United States
  • Employees 131 as on 31 Dec, 2024
  • Founders Kris Vaddi
  • Stage Public
  • Sectors
    Healthcare
  • Email
    ***********
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Prelude Therapeutics Incorporated
Operational Areas
Healthcare → Healthcare Products & Supplies
Key Metrics
  • Annual Revenue
    $7 M
    0
    as on Dec 31, 2024
  • Net Profit
    $-127.17 M
    -4.38
    as on Dec 31, 2024
  • EBITDA
    $-137.94 M
    -5.21
    as on Dec 31, 2024
  • Total Equity Funding
    $145 M (USD)

    in 4 rounds

  • Latest Funding Round
    $50 M (USD), Series C

    Aug 24, 2020

  • Investors
  • Employee Count
    131

    as on Dec 31, 2024

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IPO & Listings of Prelude Therapeutics

Prelude Therapeutics is a publicly listed company on the NASDAQ with ticker symbol PRLD in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

Exchange: NASDAQ · Ticker: PRLD . Sector: Health technology · USA

Products & Services of Prelude Therapeutics

Prelude Therapeutics offers a comprehensive portfolio of products and services, including SMARCA2 Degraders, KAT6A Degraders, Precision ADCs, and CDK Inhibitors. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.

Primary

SMARCA2 degraders are developed for cancer treatment efficacy.

KAT6A degraders are designed for breast cancer treatment.

Precision ADCs are created for targeted cancer therapy.

CDK inhibitors are formulated for various cancer treatments.

People of Prelude Therapeutics
Headcount 50-200
Employee Profiles 45
Board Members and Advisors 5
Employee Profiles
People
Jane Huang
President & Chief Medical Officer
People
Bill Novotny
SVP of Clinical Development
People
Aimee Crombie
SVP & Head of Strategic Planning & Operations
People
Michele Porreca
Chief People Officer

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Funding Insights of Prelude Therapeutics

Prelude Therapeutics has successfully raised a total of $145M across 4 strategic funding rounds. The most recent funding activity was a Series C round of $50 million completed in August 2020. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 4
  • Last Round Series C — $50.0M
  • First Round

    (11 Jul 2016)

  • Investors Count 2
Date Amount Transaction Name Valuation Lead Investors Investors
Aug, 2020 Amount Series C - Prelude Therapeutics Valuation Fidelity Investments
Jun, 2019 Amount Series B - Prelude Therapeutics Valuation Orbimed
Aug, 2018 Amount Series B - Prelude Therapeutics Valuation

investors

Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

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Investors in Prelude Therapeutics

Prelude Therapeutics has secured backing from 2 investors, including venture fund and institutional investors. Prominent investors backing the company include Fidelity Investments and Orbimed. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Investor Description Founded Year Domain Location
Investments are made by OrbiMed in global healthcare innovations across biopharmaceuticals and related fields.
Founded Year Domain Location
Provider of brokerage accounts, retirement planning, wealth management, and trading platforms
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by Prelude Therapeutics

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016

Financial Statements - Prelude Therapeutics

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Prelude Therapeutics Comparisons

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Competitors of Prelude Therapeutics

Prelude Therapeutics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Jazz Pharmaceuticals, Revolution Medicines, Blueprint Medicines, Syndax and C4 Therapeutics, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Novel biopharmaceutical medicines are developed for unmet medical needs.
domain founded_year HQ Location
Cancer therapies are developed using selective pathway inhibitors.
domain founded_year HQ Location
Selective kinase inhibitors are developed for genomically defined cancers.
domain founded_year HQ Location
Targeted therapies for cancer treatment are developed.
domain founded_year HQ Location
Small-molecule drugs for cancer treatment are developed via Degronimid platform.
domain founded_year HQ Location
Small molecule therapeutics for cancer treatment are developed.
Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

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Frequently Asked Questions about Prelude Therapeutics

When was Prelude Therapeutics founded?

Prelude Therapeutics was founded in 2016.

Where is Prelude Therapeutics located?

Prelude Therapeutics is headquartered in Philadelphia, United States. It is registered at Philadelphia, Pennsylvania, United States.

Who is the current CEO of Prelude Therapeutics?

Kris Vaddi is the current CEO of Prelude Therapeutics. They have also founded this company.

Is Prelude Therapeutics a funded company?

Prelude Therapeutics is a funded company, having raised a total of $145M across 4 funding rounds to date. The company's 1st funding round was a Series B of $30M, raised on Jul 11, 2016.

How many employees does Prelude Therapeutics have?

As of Dec 31, 2024, the latest employee count at Prelude Therapeutics is 131.

What is the annual revenue of Prelude Therapeutics?

Annual revenue of Prelude Therapeutics is $7M as on Dec 31, 2024.

What does Prelude Therapeutics do?

Prelude Therapeutics is engaged in the discovery and development of innovative cancer medicines. The company specializes in precision oncology, targeting high unmet needs with novel drug candidates. Programs include first-in-class SMARCA2 and KAT6A degraders, alongside precision antibody-drug conjugates (ADCs). Their expertise in targeted protein degradation is leveraged to advance next-generation therapies. Collaborations with partners like AbCellera enhance their ADC development. The focus remains on extending precision medicine benefits to cancer patients across various tumor types and resistance mechanisms.

Who are the top competitors of Prelude Therapeutics?

Prelude Therapeutics's top competitors include Jazz Pharmaceuticals, C4 Therapeutics and argenx.

What products or services does Prelude Therapeutics offer?

Prelude Therapeutics offers SMARCA2 Degraders, KAT6A Degraders, Precision ADCs, and CDK Inhibitors.

Is Prelude Therapeutics publicly traded?

Yes, Prelude Therapeutics is publicly traded on NASDAQ under the ticker symbol PRLD.

Who are Prelude Therapeutics's investors?

Prelude Therapeutics has 2 investors. Key investors include Fidelity Investments, and Orbimed.

What is Prelude Therapeutics's ticker symbol?

The ticker symbol of Prelude Therapeutics is PRLD on NASDAQ.

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