Silence Therapeutics

London, United Kingdom Founded: 1999 • Age: 27 yrs
RNA therapeutics for hematology and cardiovascular diseases are developed.
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About Silence Therapeutics

Silence Therapeutics is a company based in London (United Kingdom) founded in 1999.. The company has 116 employees as of December 31, 2024. Silence Therapeutics has completed 1 acquisition, including Intradigm Corporation. Silence Therapeutics operates in a competitive market with competitors including BridgeBio, Spark Therapeutics, Alnylam, ATAI and Insitro, among others.

  • Headquarter London, United Kingdom
  • Employees 116 as on 31 Dec, 2024
  • Stage Public
  • Sectors
    Healthcare
    Technology
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Silence Therapeutics, Plc.
Operational Areas
Healthcare → Healthcare Products & Supplies
Technology → Quantum & Emerging Technologies
Healthcare → Biotechnology, Genomics & Life Sciences Research
Key Metrics
  • Annual Revenue
    $42.35 M
    30.7
    as on Dec 31, 2024
  • Net Profit
    $-44.36 M
    20.12
    as on Dec 31, 2024
  • EBITDA
    $-47.96 M
    9.6
    as on Dec 31, 2024
  • Latest Funding Round
    $120 M (USD), Post-IPO

    May 25, 2021

  • Investors
    Astrazeneca

    & 5 more

  • Employee Count
    116

    as on Dec 31, 2024

  • Investments & Acquisitions
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IPO & Listings of Silence Therapeutics

Silence Therapeutics is a publicly listed company on the OTC with ticker symbol SLNCF in USA, operating in the Commercial services sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

Exchange: OTC · Ticker: SLNCF . Sector: Commercial services · USA
People of Silence Therapeutics
Headcount 50-200
Employee Profiles 34
Board Members and Advisors 12
Employee Profiles
People
J.P. Gabriel
Chief Technical Operations Officer
People
Jaimin B. Shah
Svp, General Counsel
People
Rhonda Hellums
CFO
People
Clare Elliott Cgma Acma
Senior Director, Head Of Fp&a

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Board Members and Advisors
people
James Ede-Golightly
Non-Executive Director
people
Alistair Gray
Senior Independent Non-Executive Director
people
Annemieke Aartsma-Rus
Scientific Advisor
people
Henry Ginsberg
Scientific Advisor

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Funding Insights of Silence Therapeutics

  • Total Funding
  • Total Rounds 11
  • Last Round Post-IPO — $120.0M
  • First Round

    (16 Dec 2009)

  • Investors Count 6
Date Amount Transaction Name Valuation Lead Investors Investors
May, 2021 Amount Post-IPO - Silence Therapeutics Valuation

investors

Feb, 2021 Amount Post-IPO - Silence Therapeutics Valuation

investors

Apr, 2020 Amount Post-IPO - Silence Therapeutics Valuation

investors

Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Investors in Silence Therapeutics

Silence Therapeutics has secured backing from 6 investors, including institutional and venture fund investors. Prominent investors backing the company include Astrazeneca, Mallinckrodt Pharmaceuticals and Adage Capital Management. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Investor Description Founded Year Domain Location
US private equity investments are managed by BVF Partners.
Founded Year Domain Location
-
Founded Year Domain Location
Private equity firm focused on company buyouts
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by Silence Therapeutics

Silence Therapeutics has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include Intradigm Corporation. These strategic investments and acquisitions demonstrate the company's commitment to growth through portfolio expansion, market consolidation, technology integration, and strategic partnerships that enhance competitive positioning and drive long-term value creation.

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Acquisitions
Company Name Description Domain Location Founded Year Amount
Develops RNA interference (RNAi) therapeutics for the treatment of cancer.
2000
Company Name Description Domain Location Founded Year Amount
OVO is recognized as a smart digital payment application.
2017
Bionic investment advisor platform
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014

Financial Statements - Silence Therapeutics

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Silence Therapeutics Comparisons

Employees
+
Add Comparison
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Competitors of Silence Therapeutics

Silence Therapeutics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as BridgeBio, Spark Therapeutics, Alnylam, ATAI and Insitro, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Therapeutics for genetic diseases are developed through targeted interventions.
domain founded_year HQ Location
Gene therapies for rare diseases including retinal dystrophies are developed.
domain founded_year HQ Location
RNA interference-based therapeutics are developed for multiple disorders.
domain founded_year HQ Location
A biopharmaceutical company accelerating innovative mental health treatments.
domain founded_year HQ Location
An AI-enabled platform is developed for infectious disease treatment.
domain founded_year HQ Location
Therapeutics for rare and ultra-rare metabolic diseases are developed.
Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

Latest news on Silence Therapeutics

Frequently Asked Questions about Silence Therapeutics

When was Silence Therapeutics founded?

Silence Therapeutics was founded in 1999 and raised its 1st funding round 10 years after it was founded.

Where is Silence Therapeutics located?

Silence Therapeutics is headquartered in London, United Kingdom. It is registered at London, England, United Kingdom.

How many employees does Silence Therapeutics have?

As of Dec 31, 2024, the latest employee count at Silence Therapeutics is 116.

What is the annual revenue of Silence Therapeutics?

Annual revenue of Silence Therapeutics is $42.35M as on Dec 31, 2024.

What does Silence Therapeutics do?

Founded in 1999 and headquartered in London, United Kingdom, RNA therapeutics are developed by the company for hematology and cardiovascular diseases. The pipeline features gene silencing approaches, including one that targets the Lipoprotein(A) gene to reduce risks of heart disease and stroke, and another that silences the TMPRSS6 gene to regulate iron levels in the body. Operations focus on advancing these treatments through clinical development.

Who are the top competitors of Silence Therapeutics?

Silence Therapeutics's top competitors include Spark Therapeutics, BridgeBio and Forge Biologics.

Is Silence Therapeutics publicly traded?

Yes, Silence Therapeutics is publicly traded on OTC under the ticker symbol SLNCF.

How many acquisitions has Silence Therapeutics made?

Silence Therapeutics has made 1 acquisition, including Intradigm Corporation.

Who are Silence Therapeutics's investors?

Silence Therapeutics has 6 investors. Key investors include Astrazeneca, Mallinckrodt Pharmaceuticals, Adage Capital Management, BVF Partners, and Consonance Capital.

What is Silence Therapeutics's ticker symbol?

The ticker symbol of Silence Therapeutics is SLNCF on OTC.

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