Tango Therapeutics

Cambridge, United States Founded: 2017 • Age: 9 yrs Listed
Novel cancer drugs are developed using synthetic lethality screening.

About Tango Therapeutics

Tango Therapeutics is a publicly listed company based in Cambridge (United States) founded in 2017. It operates as a novel cancer drugs are developed using synthetic lethality screening. Tango Therapeutics has raised $165 million across 5 funding rounds from investors including Gilead, Casdin Capital and Boxer Capital. The company has 155 employees. Its chief executive is Barbara Weber. Its website tangotx.com draws about 17 thousand monthly visits. Tango Therapeutics offers products and services including PRMT5 Program and CoREST Program. Its focus areas include Life Sciences, Genomics, Genomics Research and Biomarker Discovery. Its competitors include Jazz Pharmaceuticals, C4 Therapeutics, Erasca, Metabolon and MiRagen and 2 more; 7 of its 7 listed competitors have raised funding.

Company details

Tango Therapeutics was founded in 2017 in Cambridge, United States, as a biotechnology firm focused on oncology. Precision therapies are created by identifying genetic vulnerabilities in tumor suppressor genes through DNA sequencing and CRISPR-based functional screens. Targets are selected for specific patient subgroups, exploiting synthetic lethality to induce tumor cell death while sparing healthy cells. Operations center on early-stage drug discovery in the precision medicine sector.

  • Headquarters Cambridge, United States
  • Employees 155
  • Stage Public
  • Sectors
    Healthcare
  • Website category Health · Biotechnology and Pharmaceuticals
  • Email
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  • Phone
    β€’β€’β€’β€’ β€’β€’β€’β€’
  • Website tangotx.com
  • Social LinkedIn
  • Legal Name Tango Therapeutics, Inc.
Key Metrics
  • Annual Revenue
    $62.38 M (USD)
    48.29
    as on Dec 31, 2025
  • Net Profit
    -$101.59 M (USD)
    22.03
    as on Dec 31, 2025
  • EBITDA
    -$109.01 M (USD)
    23.82
    as on Dec 31, 2025
  • Total Equity Funding
    $165M (USD)

    in 5 rounds

  • Latest Funding Round
    $15M (USD), Post-IPO

    Oct 2025

  • Investors
    Gilead

    & 4 more

  • Employee Count
    155

Products & Services of Tango Therapeutics

Tango Therapeutics offers a comprehensive portfolio of products and services, including PRMT5 Program and CoREST Program.

PRMT5 Program
Oncology Therapy

Targets tumors using synthetic lethality for precision medicine.

CoREST Program
Oncology Therapy

Develops targeted therapies for cancer treatment approaches.

Funding Insights of Tango Therapeutics

Tango Therapeutics has successfully raised a total of $165M across 5 strategic funding rounds. The most recent funding activity was a Post-IPO round of $15 million completed in October 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $165M
  • Total Rounds 5
  • Last Round Post-IPO β€” $15M
  • First Round $55M

    (Mar 2017)

  • Investors Count 5

All 5 funding rounds of Tango Therapeutics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Oct 2025$15MPost-IPO––
–
Aug 2023$80MPost-IPO––
–
Aug 2020$50MSeries B–Casdin Capital
Apr 2020$60MSeries B–Boxer Capital
Mar 2017$55MSeries A––
Valuation history

5 investors in total: 5 institutional.

Investors in Tango Therapeutics

Tango Therapeutics has secured backing from 5 investors, including venture fund and institutional investors. Prominent investors backing the company include Gilead, Casdin Capital and Boxer Capital.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Investing in Life Sciences sectors like Healthcare and Biotechnology.
–casdincapital.com-
Biotech startups are funded by this venture capital firm.
–boxercap.comSan Diego, United States
Tavistock Group is engaged in global diversified investments.
–tavistock.com-
Venture capital funding is provided to early-stage life science companies.
–thirdrockventures.comBoston, United States
Developer of medicines to treat HIV/AIDS, liver diseases, cancer & others
1987gilead.comFoster City, United States
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People of Tango Therapeutics

99 people are tracked at Tango Therapeutics (56 in leadership, 11 in board & advisors, 32 in team); the tracked headcount is 155.

NameRoleGroup
Barbara Weber
CEO & PresidentLeadership
Adam Crystal
President, Research & DevelopmentLeadership
Eric Robertson
Director, Clinical ComplianceLeadership
Laurie Callen
Vice President, BiometricsLeadership
Maxim Pimkin
Senior Director, Clinical DevelopmentLeadership
Heather Dibenedetto
VP of Development OperationsLeadership
Daniella Beckman
Chief Financial OfficerLeadership
Hongming Li
Director, Process Chemistry, CMCLeadership
Jon Come
Senior DirectorLeadership
Abi O'Hare
Head Of Talent AcquisitionLeadership
Elizabeth Hickin
Vp, Investor Relations And Corporate CommunicationsLeadership
Leanne Ahronian
Associate DirectorLeadership
Sandra Sutera
Vp, Head Of Program & Portfolio Management, Chief Of Staff To The President Of R&dLeadership
Katie Woolford
Associate Director Clinical OperationsLeadership
Jen Morawiak
Director, Clinical TrialsLeadership
Donna Fitzgerald
Director, Clinical SciencesLeadership
Jannik N. Andersen
Chief Scientific OfficerLeadership
Michael Palmieri
Head of Chemistry, Manufacturing, & ControlsLeadership
William Mallender
VP of BiochemistryLeadership
Sean Hetherman
Senior Director, Corporate ControllerLeadership

79 more people are available in the full profile.

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IPO & Listings of Tango Therapeutics

Tango Therapeutics is a publicly listed company on the NASDAQ with ticker symbol TNGX in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

  • IPO date08 Apr 2021
  • Listed onNASDAQ: TNGX
  • Listed entityTango Therapeutics, Inc.
  • Exchange sectorHealth technology
  • ISINUS87583X1090
  • Share price$22.22 (-8.07% on the day) · 2026-10-13
  • Market capitalisation$3.75B
  • EPS (diluted, trailing year)$-0.84
  • Volume (last session)9,619,155

Financials of Tango Therapeutics

Exchange-reported annual figures
YearRevenueNet incomeEBITDA
2025$62.4M-$101.6M-$109.0M
2024$42.1M-$130.3M-$143.1M
2023$36.5M-$101.7M-$111.8M
2022$24.9M-$108.2M-$107.0M
2021$37.0M-$58.2M-$56.2M
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Detailed financial statements for Tango Therapeutics

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Timeline of Tango Therapeutics

4 dated milestones of Tango Therapeutics across 8 years, from founding to its latest funding, stage changes and deals.

  1. Founded Tango Therapeutics is founded.
  2. Funding First funding round of $55.0M.
  3. IPO Lists on the stock exchange (IPO).
  4. Funding Latest funding round, Post-IPO, of $15.0M.

Competitors of Tango Therapeutics

Tango Therapeutics has 7 listed competitors in our database, 7 of them funded. They include Jazz Pharmaceuticals, C4 Therapeutics, Erasca, Metabolon and MiRagen, among others.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
jazzpharma.com2003Dublin, Ireland$265M2,800
Novel biopharmaceutical medicines are developed for unmet medical needs.
c4therapeutics.com2016Cambridge, United States$223M121
Small-molecule drugs for cancer treatment are developed via Degronimid platform.
erasca.com2018San Diego, United States$300M120
Small molecule therapeutics for cancer treatment are developed.
metabolon.com2000Morrisville, United States$165.87M189
Solutions for biomarker discovery and diagnostic testing are provided.
miragen.com2007Boulder, United States$111.29M92
MicroRNA-based therapeutics are developed for treating multiple diseases.
mereobiopharma.com2015London, United Kingdom$119M56
Therapeutics for cancer and rare diseases are developed.
nimbustx.com2009Cambridge, United States$685M81
Targeted therapeutics for cancer, metabolic, and inflammatory diseases are developed.
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Detailed competitors of Tango Therapeutics

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Web traffic of Tango Therapeutics

The website of Tango Therapeutics (tangotx.com) receives about 16.5K visits a month and ranks #1,726,028 among all websites worldwide, #2,338 in Biotechnology and Pharmaceuticals.

  • Monthly visits
    16.5K

    ▲ 61% vs previous month

  • Unique visitors
    4K

    per month

  • Global rank
    #1,726,028

    among all websites

  • Category rank
    #2,338

    Health · Biotechnology and Pharmaceuticals

Similar websites

Websites whose visitors overlap most with Tango Therapeutics. Affinity shows how closely the audiences match.

WebsiteDomainAudience affinityMonthly visitsGlobal rankProfile
biopharmadive.com
100%
680.7K#208,628View details
oncologypipeline.com
100%
76.4K#510,302View details
ispor.org
ispor.org
60%
–#299,577–

Top companies in Genomics & Gene Therapy Platforms

10 companies that operate in the same segment as Tango Therapeutics (Genomics & Gene Therapy Platforms), ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Digital sequencing technology for cancer detection is developed.
2012Redwood City, California, United StatesUSD 557.5 MUSD 982.02 M4,867
Circulating tumor DNA is screened for early cancer detection.
2016Menlo Park, California, United StatesUSD 2 BUSD 147.17 M1,141
Nanopore-based electronic systems for single-molecule analysis are developed.
2005Oxford, Oxfordshire, United KingdomUSD 1.34 BUSD 301.49 M1,372
Provider of genetic test solutions to study ancestry, genealogy, and inherited traits
2006Sunnyvale, California, United StatesUSD 943.53 MUSD 189.9 M562
Provider of DNA testing services to create a family tree and ancestor
2003Yehud, Central District, IsraelUSD 40 M––
Genetically modified cell lines are developed using AAV gene-editing platform.
2007Cambridge, Cambridgeshire, United KingdomUSD 46.29 M––
Gene therapies for rare diseases including retinal dystrophies are developed.
2013Philadelphia, Pennsylvania, United StatesUSD 82.8 MUSD 64.73 M822
Therapeutics for genetic diseases are developed through targeted interventions.
2015Palo Alto, California, United StatesUSD 434.2 MUSD 502.08 M730
Provider of an online genealogy platform offering a host of services
1996Lehi, Utah, United StatesUSD 146.2 M––
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Related news about Tango Therapeutics

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Frequently Asked Questions about Tango Therapeutics

Tango Therapeutics was founded in 2017.

Tango Therapeutics is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.

Barbara Weber is the current CEO of Tango Therapeutics.

Tango Therapeutics is a funded company, having raised a total of $165M across 5 funding rounds to date. The company's 1st funding round was a Series A of $55M, raised on Mar 2017.

Tango Therapeutics has 155 employees.

Annual revenue of Tango Therapeutics is $62.38M as on Dec 31, 2025.

Tango Therapeutics was founded in 2017 in Cambridge, United States, as a biotechnology firm focused on oncology. Precision therapies are created by identifying genetic vulnerabilities in tumor suppressor genes through DNA sequencing and CRISPR-based functional screens. Targets are selected for specific patient subgroups, exploiting synthetic lethality to induce tumor cell death while sparing healthy cells. Operations center on early-stage drug discovery in the precision medicine sector.

Tango Therapeutics's top competitors include Jazz Pharmaceuticals, C4 Therapeutics and Erasca.

Tango Therapeutics offers PRMT5 Program and CoREST Program.

Yes, Tango Therapeutics is publicly traded on NASDAQ under the ticker symbol TNGX.

Tango Therapeutics has 5 investors. Key investors include Gilead, Casdin Capital, Boxer Capital, Tavistock Group, and Third Rock Ventures.

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