About XtalPi
XtalPi is a company based in Cambridge (United States) founded in 2014. XtalPi has raised $783.5 million across 7 funding rounds from investors including Google, Tencent and Mirae Asset. The company has 809 employees as of December 31, 2024. XtalPi has completed 1 acquisition, including Liverpool ChiroChem. XtalPi operates in a competitive market with competitors including Formation Bio, Owkin, BigHat, Benchsci and Predictive Oncology, among others.
- Headquarter Cambridge, United States
- Employees 809 as on 31 Dec, 2024
- Stage Public
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Sectors
HealthcareTechnology
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Phone
Locked
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Website
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Social
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- Legal Name Xtalpi Holdings Limited
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Annual Revenue
$37.19 M (USD)49.88as on Dec 31, 2024
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Net Profit
-$211.16 M (USD)22.27as on Dec 31, 2024
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EBITDA
-$90.11 M (USD)5.39as on Dec 31, 2024
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Total Equity Funding
$783.5 M (USD)
in 7 rounds
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Latest Funding Round
$268 M (USD), Post-IPO
Sep 17, 2025
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Investors
Google
& 20 more
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Employee Count
809
as on Dec 31, 2024
- Investments & Acquisitions
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IPO & Listings of XtalPi
XtalPi is a publicly listed company on the HKEX with ticker symbol 2228 in Hong Kong, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.
People of XtalPi
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Funding Insights of XtalPi
XtalPi has successfully raised a total of $783.5M across 7 strategic funding rounds. The most recent funding activity was a Post-IPO round of $268 million completed in September 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.
Investors in XtalPi
XtalPi has secured backing from 21 investors, including venture fund and institutional investors. Prominent investors backing the company include Google, Tencent and Mirae Asset.
| Investor | Description | Founded Year | Domain | Location |
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Investments are made by OrbiMed in global healthcare innovations across biopharmaceuticals and related fields.
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A venture capital firm focused on technology and innovation investments.
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Venture capital and private equity investments are made across technologies.
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Investor details for XtalPi
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Investments & Acquisitions by XtalPi
XtalPi has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include Liverpool ChiroChem.
Investment portfolio details for XtalPi
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| Company Name | Description | Domain | Location | Founded Year | Amount |
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Small organic molecules are supplied for biotech and pharmaceutical R&D.
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Locked | Locked | 2014 | Locked |
Complete acquisition details for XtalPi
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Financial Statements - XtalPi
Detailed financials for XtalPi
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Xtalpi Comparisons
Peer comparison for XtalPi
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Competitors of XtalPi
XtalPi operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Formation Bio, Owkin, BigHat, Benchsci and Predictive Oncology, among others.
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AI-powered drug discovery platform for various diseases
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An agentic AI platform is developed for biomedical research insights.
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Antibody therapies are developed through machine learning and synthetic biology.
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AI platform used for extracting antibody data from scientific papers.
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AI-based platform for cancer diagnostics and precision medicine is utilized.
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AI-driven drug discovery platform for the treatment of cancer
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Detailed competitors of XtalPi
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Latest news on Xtalpi
Complete news archive for XtalPi
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Frequently Asked Questions about XtalPi
XtalPi was founded in 2014 and raised its 1st funding round 1 year after it was founded.
XtalPi is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.
XtalPi is a funded company, having raised a total of $783.5M across 7 funding rounds to date.
As of Dec 31, 2024, the latest employee count at XtalPi is 809.
Annual revenue of XtalPi is $37.19M as on Dec 31, 2024.
XtalPi has developed a proprietary technology FACES(Fast Accurate Crystalline Engineering System), which is a cloud-based computing system to predict the crystal structure which will identify polymorphs of the compound. The companys algorithms are integrated with the Amazon Web Service (AWS) high-performance computing (HPC) resources in the cloud. The team claims to have a strong background in quantum physics and machine learning. It provides services to pharmaceutical companies at various stages of drug development. The company has deployed its technology to develop an Intelligent Digital Drug Discovery and Development (ID4) platform to improve the efficiency, accuracy, and success rate of drug discovery.
XtalPi's top competitors include Owkin, Formation Bio and Benchsci.
Yes, XtalPi is publicly traded on HKEX under the ticker symbol 2228.
XtalPi has made 1 acquisition, including Liverpool ChiroChem.
XtalPi has 21 investors. Key investors include Google, Tencent, Mirae Asset, CICC, and Orbimed.
The ticker symbol of XtalPi is 2228 on HKEX.
The valuation of XtalPi is $2.01B as of Aug 2021.