About XtalPi
XtalPi is a company based in Cambridge (United States) founded in 2014.. XtalPi has raised $783.5 million across 7 funding rounds from investors including Google, Tencent and Mirae Asset. The company has 809 employees as of December 31, 2024. XtalPi has completed 1 acquisition, including Liverpool ChiroChem. XtalPi operates in a competitive market with competitors including Formation Bio, Owkin, BigHat, Benchsci and Predictive Oncology, among others.
- Headquarter Cambridge, United States
- Employees 809 as on 31 Dec, 2024
- Stage Public
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Sectors
HealthcareTechnology
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Phone
*********
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Website
*********
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Social
*********
- Legal Name Xtalpi Holdings Limited
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Annual Revenue
$37.19 M (USD)49.88as on Dec 31, 2024
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Net Profit
$-211.16 M (USD)22.27as on Dec 31, 2024
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EBITDA
$-90.11 M (USD)5.39as on Dec 31, 2024
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Total Equity Funding
$783.5 M (USD)
in 7 rounds
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Latest Funding Round
$268 M (USD), Post-IPO
Sep 17, 2025
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Investors
Google
& 20 more
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Employee Count
809
as on Dec 31, 2024
- Investments & Acquisitions
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IPO & Listings of XtalPi
XtalPi is a publicly listed company on the HKEX with ticker symbol 2228 in Hong Kong, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.
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Funding Insights of XtalPi
XtalPi has successfully raised a total of $783.5M across 7 strategic funding rounds. The most recent funding activity was a Post-IPO round of $268 million completed in September 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.
- Total Funding Total Funding
- Total Rounds 7
- Last Round Post-IPO — $268.0M
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First Round
First Round
(01 Jun 2015)
- Investors Count 21
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Sep, 2025 | Amount | Post-IPO - XtalPi | Valuation |
investors |
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| Feb, 2025 | Amount | Post-IPO - XtalPi | Valuation |
investors |
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| Aug, 2021 | Amount | Series D - XtalPi | Valuation | Orbimed |
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
Investors in XtalPi
XtalPi has secured backing from 21 investors, including venture fund and institutional investors. Prominent investors backing the company include Google, Tencent and Mirae Asset. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.
| Investor | Description | Founded Year | Domain | Location |
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Investments are made by OrbiMed in global healthcare innovations across biopharmaceuticals and related fields.
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Founded Year | Domain | Location | |
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A venture capital firm focused on technology and innovation investments.
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Founded Year | Domain | Location | |
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Venture capital and private equity investments are made across technologies.
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Founded Year | Domain | Location |
| Investor | Description | Founded Year | Domain | Location |
|---|---|---|---|---|
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Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
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Founded Year | Domain | Location | |
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Startup ecosystems are ignited through strategic investments by Signite Partners.
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Founded Year | Domain | Location | |
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Venture capital is directed toward companies in multiple sectors.
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Founded Year | Domain | Location | |
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Venture capital is invested in cybersecurity, fintech, and AI startups.
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Founded Year | Domain | Location |
Investments & Acquisitions by XtalPi
XtalPi has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include Liverpool ChiroChem. These strategic investments and acquisitions demonstrate the company's commitment to growth through portfolio expansion, market consolidation, technology integration, and strategic partnerships that enhance competitive positioning and drive long-term value creation.
| Company Name | Description | Domain | Location | Founded Year | Amount |
|---|---|---|---|---|---|
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Bionic investment advisor platform
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2016 | ||||
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Fine Asian gourmet food is offered by an internet-first restaurant.
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2016 | ||||
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Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
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2014 | ||||
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Fine Asian gourmet food is offered by an internet-first restaurant.
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2016 |
| Company Name | Description | Domain | Location | Founded Year | Amount |
|---|---|---|---|---|---|
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Small organic molecules are supplied for biotech and pharmaceutical R&D.
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2014 |
| Company Name | Description | Domain | Location | Founded Year | Amount |
|---|---|---|---|---|---|
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OVO is recognized as a smart digital payment application.
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2017 | ||||
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Bionic investment advisor platform
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2016 | ||||
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Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
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2014 | ||||
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Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
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2014 |
Financial Statements - XtalPi
| Date | Amount | Transaction Name | Valuation | Lead Investors | Investors |
|---|---|---|---|---|---|
| Jul, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Jan, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
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| Feb, 2021 | Amount | Post-IPO - Grab | Valuation |
investors |
Xtalpi Comparisons
Competitors of XtalPi
XtalPi operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Formation Bio, Owkin, BigHat, Benchsci and Predictive Oncology, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.
| Company Name | Domain | Founded year | HQ Location | Description |
|---|---|---|---|---|
| domain | founded_year | HQ Location |
AI-powered drug discovery platform for various diseases
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| domain | founded_year | HQ Location |
An agentic AI platform is developed for biomedical research insights.
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| domain | founded_year | HQ Location |
Antibody therapies are developed through machine learning and synthetic biology.
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| domain | founded_year | HQ Location |
AI platform used for extracting antibody data from scientific papers.
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| domain | founded_year | HQ Location |
AI-based platform for cancer diagnostics and precision medicine is utilized.
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| domain | founded_year | HQ Location |
AI-driven drug discovery platform for the treatment of cancer
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| Company Name | Domain | Founded year | HQ Location | Description |
|---|---|---|---|---|
| domain | founded_year | HQ Location |
Multiple services are booked via an app-based platform.
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| domain | founded_year | HQ Location |
On-demand services are booked through an app-based platform.
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| domain | founded_year | HQ Location |
App based platform offering on demand delivery and ride-hailing services
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| domain | founded_year | HQ Location |
Operates an on-demand hyperlocal delivery app for food and groceries.
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Latest news on Xtalpi
Frequently Asked Questions about XtalPi
When was XtalPi founded?
XtalPi was founded in 2014 and raised its 1st funding round 1 year after it was founded.
Where is XtalPi located?
XtalPi is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.
Is XtalPi a funded company?
XtalPi is a funded company, having raised a total of $783.5M across 7 funding rounds to date. The company's 1st funding round was a Series D of $400M, raised on Jun 01, 2015.
How many employees does XtalPi have?
As of Dec 31, 2024, the latest employee count at XtalPi is 809.
What is the annual revenue of XtalPi?
Annual revenue of XtalPi is $37.19M as on Dec 31, 2024.
What does XtalPi do?
XtalPi has developed a proprietary technology FACES(Fast Accurate Crystalline Engineering System), which is a cloud-based computing system to predict the crystal structure which will identify polymorphs of the compound. The companys algorithms are integrated with the Amazon Web Service (AWS) high-performance computing (HPC) resources in the cloud. The team claims to have a strong background in quantum physics and machine learning. It provides services to pharmaceutical companies at various stages of drug development. The company has deployed its technology to develop an Intelligent Digital Drug Discovery and Development (ID4) platform to improve the efficiency, accuracy, and success rate of drug discovery.
Who are the top competitors of XtalPi?
XtalPi's top competitors include Owkin, Formation Bio and Benchsci.
Is XtalPi publicly traded?
Yes, XtalPi is publicly traded on HKEX under the ticker symbol 2228.
How many acquisitions has XtalPi made?
XtalPi has made 1 acquisition, including Liverpool ChiroChem.
Who are XtalPi's investors?
XtalPi has 21 investors. Key investors include Google, Tencent, Mirae Asset, CICC, and Orbimed.
What is XtalPi's ticker symbol?
The ticker symbol of XtalPi is 2228 on HKEX.
What is XtalPi's valuation?
The valuation of XtalPi is $2.01B as of Aug 2021.
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