Checkmate Pharmaceuticals

Cambridge, United States Founded: 2015 • Age: 11 yrs Listed Acquired By Regeneron Pharmaceuticals
Oligonucleotides for cancer immunotherapy are developed via innate immune activation.

About Checkmate Pharmaceuticals

Checkmate Pharmaceuticals is a Healthcare company based in Cambridge (United States) founded in 2015, and was acquired by Regeneron Pharmaceuticals in April 2022. It operates as an oligonucleotides for cancer immunotherapy are developed via innate immune activation. Checkmate Pharmaceuticals has raised $175.08 million across 6 funding rounds from investors including Regeneron Pharmaceuticals, BrightEdge and Longitude Capital. The company has 16 employees. The company was acqui-hired. Its focus areas include Life Sciences, Immunotherapy, Vaccine and Therapeutic. Its legal entity is CHECKMATE PHARMACEUTICALS, INC. Its competitors include Moderna, Jazz Pharmaceuticals, BeiGene, Advanced Accelerator Applications and Incyte and 4 more; 8 of its 9 listed competitors have raised funding.

Company details

Founded in 2015 and based in Cambridge, United States, Checkmate Pharmaceuticals operates in the biotechnology sector. Focus is placed on research and development of CpG DNA-based therapies to stimulate the innate immune system against tumors. This approach integrates Toll-like receptor 9 activation with checkpoint inhibitors. The lead candidate, CMP-001, a CpG-A oligonucleotide, is evaluated in combination with pembrolizumab for melanoma treatment in a Phase 1b trial.

Key Metrics

Funding Insights of Checkmate Pharmaceuticals

Checkmate Pharmaceuticals has successfully raised a total of $175.08M across 6 strategic funding rounds. The most recent funding activity was a Series C round of $85.08 million completed in June 2020. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $175.08M
  • Total Rounds 6
  • Last Round Series C β€” $85.08M
  • First Round $25M

    (Feb 2017)

  • Investors Count 10

All 6 funding rounds of Checkmate Pharmaceuticals with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Jun 2020$85.08MSeries C–Longitude Capital, Novo Holdings
Apr 2020$10MDebt – Conventional––
–
Jan 2020$16MSeries B––
–
Mar 2019$22MSeries B–Decheng Capital
Jun 2017$27MSeries B–F-Prime Capital
Feb 2017$25MSeries A––
Valuation history

11 investors in total: 11 institutional.

Investors in Checkmate Pharmaceuticals

Checkmate Pharmaceuticals has secured backing from 11 investors, including venture fund and institutional investors. Prominent investors backing the company include Regeneron Pharmaceuticals, BrightEdge and Longitude Capital.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Private equity firm focused on life science sector
–longitudecapital.comMenlo Park, United States
Private equity and venture capital fund focused on the healthcare sector
–novoholdings.dkHellerup, Denmark
Early-stage life science focused VC firm investing in geographies such as Europe and the US
–medicxi.comLondon, United Kingdom
Venture capital firm
–omegafunds.comBoston, United States
Sectoral Asset Management is focused on global healthcare investment.
2000sectoral.comMontreal, Canada
Biotech funding, drug development support, and investment in life sciences.
–sofinnova.com-
A life sciences investment firm focused on novel therapeutics is operated.
2011venbio.comSan Francisco, United States
Investments in life sciences, technology, healthtech, and crypto sectors from global locations.
–fprimecapital.com-
Venture capital firm focused on life science and technology sectors
–decheng.comShanghai, China
Search engine optimization tools for enterprises are provided.
2007brightedge.comSan Mateo, United States
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Investor details for Checkmate Pharmaceuticals

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People of Checkmate Pharmaceuticals

959 people are tracked at Checkmate Pharmaceuticals (452 in leadership, 3 in board & advisors, 504 in team); the tracked headcount is 16.

NameRoleGroup
Nanita Cranford
Vice President, Global Regulatory OperationsLeadership
Kris Sprague
Global Head, Program And Project PlanningLeadership
Danielle Clemente
Director HR Business PartnerLeadership
Leslie Cascone Rohrbacker
Executive Director Human ResourcesLeadership
Barbara Forster
Senior Director, Global BenefitsLeadership
Jeanne O'Connell
Director QC Technical ResourcesLeadership
George D. Yancopoulos
President & Chief Scientific OfficerLeadership
Leonard S. Schleifer
Founder, President & CEOLeadership
Priscila Gonçalves
Senior Medical DirectorLeadership
Janie Parrino
Global Program Head, Immunology, Inflammation, And Infectious DiseasesLeadership
Nicole Dossin
Senior Director, Development Program Management (ces And Precision Medicine)Leadership
Paulina Olivo Weber
Director, Development Operations And Portfolio ManagementLeadership
Dana Pipkin
National Account DirectorLeadership
Gina Thomas
Vice President Talent AcquisitionLeadership
Humberto Lara-Guerra
Senior Medical Director Clinical SciencesLeadership
Yvette Payne
Director Hematology Field Medical TeamLeadership
Srinivasan Sadanandhamurthy
Senior Director, Data EngineeringLeadership
Frank Loganzo
Director, Solution Partner, Research & Preclinical Development ITLeadership
Colleen Scott
Director, Talent ManagementLeadership
Naveen Karumuri
Associate Director, AI Engineering.Leadership

939 more people are available in the full profile.

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Timeline of Checkmate Pharmaceuticals

5 dated milestones of Checkmate Pharmaceuticals across 7 years, from founding to its latest funding, stage changes and deals.

  1. Founded Checkmate Pharmaceuticals is founded.
  2. Funding First funding round of $25.0M.
  3. Funding Latest funding round, Series C, of $85.1M.
  4. IPO Lists on the stock exchange (IPO).
  5. Exit Acquired by Regeneron Pharmaceuticals.

Competitors of Checkmate Pharmaceuticals

Checkmate Pharmaceuticals has 9 listed competitors in our database, 8 of them funded. They include Moderna, Jazz Pharmaceuticals, BeiGene, Advanced Accelerator Applications and Incyte, among others.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
modernatx.com2010Cambridge, United States$2.78B1,312
mRNA-based therapeutics for diseases including cancer and infections are developed.
jazzpharma.com2003Dublin, Ireland$265M2,800
Novel biopharmaceutical medicines are developed for unmet medical needs.
beigene.com2010Cambridge, United States$172M1,090
Targeted and immune-oncology drugs for cancer treatment are developed.
adacap.com2002Saint Genis Pouilly, France$56.13M–
Radiopharmaceuticals for oncology diagnostics and therapies are developed and marketed.
incyte.com1991Wilmington, United States–1,387
Small molecules are developed for cancer and skin disease treatments.
revmed.com2014Redwood, United States$326.29M181
Cancer therapies are developed using selective pathway inhibitors.
blueprintmedicines.com2008Cambridge, United States$115M201
Selective kinase inhibitors are developed for genomically defined cancers.
syndax.com2005Waltham, United States$198.29M107
Targeted therapies for cancer treatment are developed.
c4therapeutics.com2016Cambridge, United States$223M121
Small-molecule drugs for cancer treatment are developed via Degronimid platform.
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Detailed competitors of Checkmate Pharmaceuticals

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Top companies in Immunology & Cancer Therapeutics

10 companies that operate in the same segment as Checkmate Pharmaceuticals (Immunology & Cancer Therapeutics), ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Antibody-based drugs are developed for autoimmune diseases and cancer treatment.
2008Ghent, East Flanders, BelgiumUSD 61.9 MUSD 1.41 B355
Targeted and immune-oncology drugs for cancer treatment are developed.
2010Cambridge, Massachusetts, United StatesUSD 172 M––
Immuno-modulatory therapies for dementia and neurodegenerative disorders are developed.
2013San Francisco, California, United StatesUSD 214.78 MUSD 21.05 M211
Targeted therapies for cancer treatment are developed.
2005Waltham, Massachusetts, United StatesUSD 198.29 MUSD 172.35 M270
Treatments for anemia and fibrosis by exploiting connective tissue growth factor (CTGF) and hypoxia-inducible factor (HIF) biology.
1993San Francisco, California, United StatesUSD 213.52 MUSD 29.62 M225
Plasma-based biologics are developed for immune deficiency and infectious diseases.
2005Ramsey, Minnesota, United StatesUSD 17.55 MUSD 510.17 M685
Antibody drugs for cancer treatment are developed.
2015Singapore, SingaporeUSD 150 M––
CAR T-cell and T-cell receptor immunotherapies for cancer are developed.
2013Seattle, Washington, United StatesUSD 316.67 M–520
Antibody-based therapeutics for cancer therapy are developed via cell-free synthesis.
2003United StatesUSD 171.85 MUSD 102.48 M338
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Frequently Asked Questions about Checkmate Pharmaceuticals

Checkmate Pharmaceuticals was founded in 2015 and raised its 1st funding round 2 years after it was founded.

Checkmate Pharmaceuticals is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.

Checkmate Pharmaceuticals is a funded company, having raised a total of $175.08M across 6 funding rounds to date. The company's 1st funding round was a Series A of $25M, raised on Feb 2017.

Checkmate Pharmaceuticals has 16 employees.

Founded in 2015 and based in Cambridge, United States, Checkmate Pharmaceuticals operates in the biotechnology sector. Focus is placed on research and development of CpG DNA-based therapies to stimulate the innate immune system against tumors. This approach integrates Toll-like receptor 9 activation with checkpoint inhibitors. The lead candidate, CMP-001, a CpG-A oligonucleotide, is evaluated in combination with pembrolizumab for melanoma treatment in a Phase 1b trial.

Checkmate Pharmaceuticals's top competitors include Moderna, Jazz Pharmaceuticals and Advanced Accelerator Applications.

Checkmate Pharmaceuticals has 11 investors. Key investors include Regeneron Pharmaceuticals, BrightEdge, Longitude Capital, Novo Holdings, and Medicxi.

Checkmate Pharmaceuticals operates through Checkmate Pharmaceuticals, Inc..

Yes. Checkmate Pharmaceuticals was acquired by Regeneron Pharmaceuticals in April 2022.

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