Helios

Tokyo, Japan Founded: 2011 • Age: 15 yrs Listed
HiPSC-derived RPE cells are developed for AMD treatment.

About Helios

Helios is a company based in Tokyo (Japan) founded in 2011. It operates as a HealthTech. Helios has raised $29.17 million across 2 funding rounds from investors including Nikon, European Union and Sumitomo Dainippon Pharma. The company has 65 employees. Helios offers products and services including iPSC Regenerative Medicine, Somatic Stem Cell Regenerative Medicine, and Cancer Immunotherapy (NK Cells). Helios operates in a competitive market with competitors including Kriya Therapeutics, Annexon, Aldeyra, Blue Rock Therapeutics and Nicox, among others.

  • Headquarter Tokyo, Japan
  • Employees 65
  • Stage Public
  • Sectors
    Healthcare
  • Website category Health · Biotechnology and Pharmaceuticals
  • Website healios.co.jp
  • Social LinkedIn
  • Legal Name Healios Kk
Key Metrics
  • Annual Revenue
    $663.81 K (USD)
    -81.43
    as on Dec 31, 2025
  • Net Profit
    -$14.17 M (USD)
    47.65
    as on Dec 31, 2025
  • EBITDA
    -$19.98 M (USD)
    -20.08
    as on Dec 31, 2025
  • Total Equity Funding
    $29.17M (USD)

    in 2 rounds

  • Latest Funding Round
    $55.99K (USD), Grant

    Jun 2019

  • Investors
    Nikon

    & 2 more

  • Employee Count
    65

Products & Services of Helios

Helios offers a comprehensive portfolio of products and services, including iPSC Regenerative Medicine, Somatic Stem Cell Regenerative Medicine, and Cancer Immunotherapy (NK Cells).

iPSC Regenerative Medicine
Regenerative Medicine

Innovative therapies are developed using iPSC technology.

Somatic Stem Cell Regenerative Medicine
Regenerative Medicine

Treatments are created using somatic stem cells.

Cancer Immunotherapy (NK Cells)
Immunotherapy

Cancer treatments are developed using NK cells.

Funding Insights of Helios

Helios has successfully raised a total of $29.17M across 2 strategic funding rounds. The most recent funding activity was a Grant round of $55.99 thousand completed in June 2019. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $29.17M
  • Total Rounds 2
  • Last Round Grant β€” $55,992
  • First Round $29.17M

    (Oct 2013)

  • Investors Count 3

All 2 funding rounds of Helios with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Jun 2019$55,992Grant––
Oct 2013$29.17MSeries A––
Valuation history

3 investors in total: 3 institutional.

Investors in Helios

Helios has secured backing from 3 investors, including institutional investors. Prominent investors backing the company include Nikon, European Union and Sumitomo Dainippon Pharma.

All
Institutional
InvestorDescriptionFounded YearDomainLocation
Government entites focused on freedom, democracy, equality and the rule of law, promoting peace and stability
1958europa.euBrussels, Belgium
Pharmaceuticals, food ingredients, additives, and veterinary products are manufactured.
1897ds-pharma.comOsaka, Japan
Nikon is recognized as a key technology solutions company.
1917nikon.comMinato, Japan
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Investor details for Helios

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IPO & Listings of Helios

Helios is a publicly listed company on the TSE with ticker symbol 4593 in Japan, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

  • IPO date16 Jun 2015
  • Listed onTSE: 4593
  • Listed entityHealios KK
  • Exchange sectorHealth technology
  • ISINJP3835100003
  • Share price302.00 JPY (+0.67% on the day) · 2026-10-09
  • Market capitalisation40,934,681,610.00 JPY
  • Price to earnings110.4
  • EPS (diluted, trailing year)2.73 JPY
  • Volume (last session)1,336,400

Financials of Helios

Exchange-reported annual figures
YearRevenueNet incomeEBITDA
2025104.0M JPY-2.22B JPY-3.13B JPY
2024560.0M JPY-4.24B JPY-2.60B JPY
2023121.0M JPY-3.82B JPY-3.01B JPY
202290.0M JPY-5.17B JPY-4.78B JPY
202141.0M JPY-4.91B JPY-5.12B JPY
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Detailed financial statements for Helios

Statement rows, ratios, five-year trends and downloadable financials of the group companies require an active premium plan.

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  • Downloads

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Timeline of Helios

4 dated milestones of Helios across 8 years, from founding to its latest funding, stage changes and deals.

  1. Founded Helios is founded.
  2. Funding First funding round of $29.2M.
  3. IPO Lists on the stock exchange (IPO).
  4. Funding Latest funding round, Grant, of $56K.

Competitors of Helios

Helios operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Kriya Therapeutics, Annexon, Aldeyra, Blue Rock Therapeutics and Nicox, among others.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
kriyatherapeutics.com2012Redwood, United States$930.93M159
Developer of therapeutic solutions for the treatment of diabetes
annexonbio.com2011San Francisco, United States$256M80
Developer of antibodies to treat complement-mediated neurodegenerative diseases
aldeyra.com2004Lexington, United States$4.79M30
Drug candidates for immune-mediated diseases are developed by Aldeyra.
bluerocktx.com2016Boston, United States$225M138
Stem cell therapies are developed for cardiovascular and neurological diseases.
nicox.com1996Valbonne, France$271.01M–
Nitric oxide-based therapeutics for glaucoma and eye conditions are developed.
gyroscope.cc2016San Francisco, United States––
Mobile SDK developed for app engagement and monetization strategies.
aspenneuroscience.com2018San Diego, United States$224M–
Provider of genomic-based personalised pluripotent stem cell therapy
meiragtx.com2015New York, United States–358
Gene therapies for ocular and neurodegenerative diseases are developed.
perceivebio.com2021San Francisco, United States$78M–
Developer of therapeutics to treat diabetes and eye diseases
alimerasciences.com2003Alpharetta, United States$66.8M79
Ophthalmic pharmaceuticals for diabetic macular edema are developed and commercialized.
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Detailed competitors of Helios

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Verified entity values are shown only after access is granted.

Web traffic of Helios

The website of Helios (healios.co.jp) receives about 26.8K visits a month and ranks #899,069 among all websites worldwide, #1,080 in Biotechnology and Pharmaceuticals.

  • Monthly visits
    26.8K

    ▼ 1% vs previous month

  • Unique visitors
    10K

    per month

  • Global rank
    #899,069

    among all websites

  • Category rank
    #1,080

    Health · Biotechnology and Pharmaceuticals

Similar websites

Websites whose visitors overlap most with Helios. Affinity shows how closely the audiences match.

WebsiteDomainAudience affinityMonthly visitsGlobal rankProfile
ptglab.co.jp
ptglab.co.jp
100%
–#676,043–
kyo-eye.org
kyo-eye.org
61%
–#1,348,363–
nipro.co.jp
60%
160.7K#244,538View details
he-lios.co.jp
he-lios.co.jp
31%
–#3,685,191–
news.yahoo.co.jp
news.yahoo.co.jp
30%
–#44–

Latest news on Helios

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Complete news archive for Helios

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Similar companies to Helios

10 companies that operate in the same segment as Helios (Cell Therapy), ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
CAR T-cell and T-cell receptor immunotherapies for cancer are developed.
2013Seattle, Washington, United StatesUSD 316.67 M–520
CAR-T and TIL immunotherapies for solid tumors are developed.
2018San Francisco, California, United StatesUSD 493 MUSD 36 K300
T-cell-based immunotherapies for cancer treatment are developed.
2000Tubingen, Baden-wurttemberg, GermanyUSD 236.4 MUSD 54.47 M423
Engineered T-cell immunotherapies are developed for cancer and auto-immune diseases.
2015London, England, United KingdomUSD 181.37 MUSD 75.56 M647
Smart surgical devices for spinal surgery are developed.
1997San Diego, California, United StatesUSD 54.1 M––
Genetically engineered cell therapies are developed for multiple disorders.
2018Seattle, Washington, United StatesUSD 821 M–194
Provider of bio-artificial pancreas for Type 1 Diabetes treatment
2015Cambridge, Massachusetts, United StatesUSD 158 M–58
T-cell and antibody-based therapeutics are developed via single-cell sequencing platforms.
2011San Francisco, California, United StatesUSD 36.13 M–36
Developer of immune cell therapies
2019San Francisco, California, United StatesUSD 631.16 M–178
Cue Biopharma is focused on developing immunotherapy solutions.
2015Cambridge, Massachusetts, United StatesUSD 10 MUSD 27.47 M41
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Frequently Asked Questions about Helios

Helios was founded in 2011 and raised its 1st funding round 2 years after it was founded.

Helios is headquartered in Tokyo, Japan. It is registered at Tokyo, Tokyo, Japan.

Helios is a funded company, having raised a total of $29.17M across 2 funding rounds to date. The company's 1st funding round was a Series A of $29.17M, raised on Oct 2013.

Helios has 65 employees.

Annual revenue of Helios is $663.81K as on Dec 31, 2025.

Helios is focused on the development of regenerative medicine therapies to expand treatment options for patients worldwide. The company operates in sectors such as iPSC regenerative medicine, somatic stem cell therapies, and cancer immunotherapy using NK cells. Solutions are being researched for conditions like age-related macular degeneration, liver diseases, stroke, and acute respiratory distress syndrome (ARDS). Innovative strategies are employed to deliver new treatment methods and hope to patients globally.

Helios's top competitors include Annexon, Alimera Sciences and MeiraGTx.

Helios offers iPSC Regenerative Medicine, Somatic Stem Cell Regenerative Medicine, and Cancer Immunotherapy (NK Cells).

Yes, Helios is publicly traded on TSE under the ticker symbol 4593.

Helios has 3 investors. Key investors include Nikon, European Union, and Sumitomo Dainippon Pharma.

Helios operates through Helios K.K..

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