Ionis

United States Founded: 1989 • Age: 37 yrs Listed
RNA-targeted medicines are developed for various diseases.

About Ionis

Ionis is a publicly listed company based in United States founded in 1989. RNA-targeted medicines are developed for various diseases. The company has 1,070 employees. Its chief executive, as recorded, is Brett P Monia. Its website ionis.com draws about 54 thousand monthly visits. Ionis offers products and services including RNA-targeted Medicines. Its focus areas include Life Sciences, Immunology, Drugs and Diversified. Its legal entity is IONIS PHARMACEUTICALS, INC. Its competitors include Moderna, BridgeBio and Spark Therapeutics; 3 of its 3 listed competitors have raised funding.

Company details

Ionis was founded in 1989 in the United States and operates in the biotechnology sector. Genetic medicines, with a focus on RNA-targeted therapeutics, are developed to target the root causes of diseases. Operations center on research and development of treatments for a range of conditions, including rare and neurological disorders. The company is headquartered in Carlsbad, California, and maintains a global presence through partnerships and clinical trials.

  • Headquarters United States
  • Employees 1,070
  • Stage Public
  • Sectors
    Healthcare
  • Website category Health · Biotechnology and Pharmaceuticals
  • Email
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  • Phone
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  • Website ionis.com
  • Social LinkedIn X Facebook Instagram
  • Legal Name Ionis Pharmaceuticals, Inc.
Key Metrics
  • Annual Revenue
    $943.71 M (USD)
    33.83
    as on Dec 31, 2025
  • Net Profit
    -$381.39 M (USD)
    15.97
    as on Dec 31, 2025
  • EBITDA
    -$358.99 M (USD)
    20.77
    as on Dec 31, 2025
  • Latest Funding Round
    $924.03K (USD), Grant

    Aug 2009

  • Investors
    HHS

    & 1 more

  • Employee Count
    1,070

Products & Services of Ionis

Ionis offers a comprehensive portfolio of products and services, including RNA-targeted Medicines.

RNA-targeted Medicines
Biopharmaceuticals

Treats serious diseases by targeting RNA molecules

Funding Insights of Ionis

  • Total Rounds 9
  • Last Round Grant β€” $924,028
  • First Round $744,910

    (Apr 2004)

  • Investors Count 2

All 9 funding rounds of Ionis with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Aug 2009$924,028Grant––
Aug 2009Grant––
Sep 2008$649,821Grant––
Sep 2008$132,885Grant––
Sep 2007$924,028Grant––
Sep 2007$924,028Grant––
Aug 2007$132,885Grant––
Jun 2006$924,028Grant––
Apr 2004$744,910Grant––
Valuation history

2 investors in total: 2 institutional.

Investors in Ionis

Ionis has secured backing from 2 investors, including institutional investors. Prominent investors backing the company include HHS and Ojp.

All
Institutional
InvestorDescriptionFounded YearDomainLocation
Public health and human services are overseen by HHS.
1953hhs.gov
Federal justice system funding, training, and resources are provided.
ojp.gov
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Investor details for Ionis

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People of Ionis

319 people are tracked at Ionis (227 in leadership, 10 in board & advisors, 82 in team); the tracked headcount is 1,070.

NameRoleGroup
Brett P Monia
CEOLeadership
Sanjay Bhanot
Vice President Metabolics & Translational MedicineLeadership
C. Frank Bennett
EVP, Chief Scientific OfficerLeadership
Kevin Cornetto
Director, Drug Safety SurveillanceLeadership
Samuel Abariga
Medical Director, Drug Safety & PharmacovigilanceLeadership
Isaac Ballesteros
Assistant Director, AccountingLeadership
Ewa Karwatowska-Prokopczuk
VP, Cardiovascular MedicineLeadership
Patrick R. O’Neil
Chief Legal Officer and General CounselLeadership
Alex Behling
Assistant Director- Biomarkers BioanalysisLeadership
Adam Mullick
VP, Drug DiscoveryLeadership
Leo Sahelijo
VP, Translational MedicineLeadership
John Su
VP, BiometricsLeadership
Shannon Devers
Executive Vice President, Chief Human Resources OfficerLeadership
Daniel Capaldi
VP, Analytical & Process ChemistryLeadership
Eric Swayze
Executive Vice President, Research At Ionis Pharmaceuticals, Inc.Leadership
Isaiah Cedillo
Executive Director, Manufacturing & OperationsLeadership
Pratap Singh
Executive Director, Clinical PharmacologyLeadership
Holly Kordasiewicz
VP, Drug DiscoveryLeadership
Eugene Schneider
Executive Vice President, Chief Clinical Development OfficerLeadership
Richard S. Geary
EVP, Chief Development OfficerLeadership

299 more people are available in the full profile.

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IPO & Listings of Ionis

Ionis is a publicly listed company on the NASDAQ with ticker symbol IONS in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

  • IPO date17 Jul 2017
  • Listed onNASDAQ: AKCA
  • Listed entityIonis Pharmaceuticals, Inc.
  • Exchange sectorHealth technology
  • ISINUS4622221004
  • Share price$42.38 (-2.95% on the day) · 2026-10-13
  • Market capitalisation$7.04B
  • EPS (diluted, trailing year)$-3.47
  • Volume (last session)2,978,032

Financials of Ionis

Exchange-reported annual figures
YearRevenueNet incomeEBITDA
2025$943.7M-$381.4M-$359.0M
2024$705.1M-$453.9M-$453.1M
2023$787.6M-$366.3M-$331.2M
2022$587.4M-$269.7M-$388.1M
2021$810.5M-$28.6M-$10.6M
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Detailed financial statements for Ionis

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Timeline of Ionis

4 dated milestones of Ionis across 28 years, from founding to its latest funding, stage changes and deals.

  1. Founded Ionis is founded.
  2. Funding First funding round of $745K.
  3. Funding Latest funding round, Grant, of $924K.
  4. IPO Lists on the stock exchange (IPO).

Competitors of Ionis

Ionis has 3 listed competitors in our database, 3 of them funded. They include Moderna, BridgeBio and Spark Therapeutics.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
modernatx.com2010Cambridge, United States$2.78B1,312
mRNA-based therapeutics for diseases including cancer and infections are developed.
bridgebio.com2015Palo Alto, United States$434.2M
Therapeutics for genetic diseases are developed through targeted interventions.
sparktx.com2013Philadelphia, United States$82.8M822
Gene therapies for rare diseases including retinal dystrophies are developed.
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Detailed competitors of Ionis

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Web traffic of Ionis

The website of Ionis (ionis.com) receives about 54.3K visits a month and ranks #738,122 among all websites worldwide, #848 in Biotechnology and Pharmaceuticals.

  • Monthly visits
    54.3K

    ▲ 17.6% vs previous month

  • Unique visitors
    21.6K

    per month

  • Global rank
    #738,122

    among all websites

  • Category rank
    #848

    Health · Biotechnology and Pharmaceuticals

Similar websites

Websites whose visitors overlap most with Ionis. Affinity shows how closely the audiences match.

WebsiteDomainAudience affinityMonthly visitsGlobal rankProfile
theratech.com
100%
5.5K#5,174,204View details
pharmashots.com
99%
#2,147,167View details
argonautms.com
98%
9.6K#2,712,987View details
pipelinereview.com
pipelinereview.com
96%
–
bioratherapeutics.com
95%
1.8K#6,912,037View details
β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’.comβ€’β€’%β€’.β€’M#‒‒‒‒‒–
β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’.comβ€’β€’%β€’.β€’M#‒‒‒‒‒–
β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’.comβ€’β€’%β€’.β€’M#‒‒‒‒‒–
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All 40 similar websites and full traffic analytics for Ionis

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Top companies in Immunology & Cancer Therapeutics

3 companies that operate in the same segment as Ionis (Immunology & Cancer Therapeutics) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Targeted and immune-oncology drugs for cancer treatment are developed.
2010Cambridge, Massachusetts, United StatesUSD 172 M
Immuno-modulatory therapies for dementia and neurodegenerative disorders are developed.
2013San Francisco, California, United StatesUSD 214.78 MUSD 21.05 M211
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Related news about Ionis

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Frequently Asked Questions about Ionis

Ionis was founded in 1989 and raised its 1st funding round 15 years after it was founded.

Ionis is headquartered in United States.

Brett P Monia is the CEO of Ionis, as recorded in our data.

Ionis has 1,070 employees.

Annual revenue of Ionis is $943.71M as on Dec 31, 2025.

Ionis was founded in 1989 in the United States and operates in the biotechnology sector. Genetic medicines, with a focus on RNA-targeted therapeutics, are developed to target the root causes of diseases. Operations center on research and development of treatments for a range of conditions, including rare and neurological disorders. The company is headquartered in Carlsbad, California, and maintains a global presence through partnerships and clinical trials.

Ionis's top competitors include Moderna, Spark Therapeutics and BridgeBio.

Ionis offers RNA-targeted Medicines.

Yes, Ionis is publicly traded on NASDAQ under the ticker symbol IONS.

Ionis has 2 investors. Key investors include HHS, and Ojp.

Ionis operates through Ionis Pharmaceuticals, Inc..

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