Iovance Biotherapeutics

San Carlos, United States Founded: 2007 • Age: 19 yrs Listed
T-cell therapies for cancer treatment are developed.

About Iovance Biotherapeutics

Iovance Biotherapeutics is a company based in San Carlos (United States) founded in 2007 by Robert T Brooke. It operates as a HealthTech. The company has 838 employees. Iovance Biotherapeutics has completed 1 acquisition, including Proleukin. Iovance Biotherapeutics offers products and services including Amtagvi and Proleukin. Iovance Biotherapeutics operates in a competitive market with competitors including Jazz Pharmaceuticals, Revolution Medicines, Blueprint Medicines, Syndax and C4 Therapeutics, among others.

  • Headquarter San Carlos, United States
  • Employees 838
  • Founders Robert T Brooke
  • Stage Public
  • Sectors
    Healthcare
  • Website category Health · Biotechnology and Pharmaceuticals
  • Email
    β€’β€’β€’β€’β€’β€’β€’β€’
  • Phone
    β€’β€’β€’β€’ β€’β€’β€’β€’
  • Website iovance.com
  • Social LinkedIn X
  • Legal Name Iovance Biotherapeutics, Inc.
Key Metrics
  • Annual Revenue
    $263.5 M (USD)
    60.6
    as on Dec 31, 2025
  • Net Profit
    -$390.98 M (USD)
    -5.05
    as on Dec 31, 2025
  • EBITDA
    -$350.89 M (USD)
    0.22
    as on Dec 31, 2025
  • Latest Funding Round
    $100M (USD), Post-IPO

    Jun 2016

  • Investors
    Orbimed

    & 2 more

  • Employee Count
    838
  • Investments & Acquisitions

Products & Services of Iovance Biotherapeutics

Iovance Biotherapeutics offers a comprehensive portfolio of products and services, including Amtagvi and Proleukin.

Amtagvi
Biotechnology

Amtagvi is developed for advanced cancer treatment therapies.

Proleukin
Biotechnology

Proleukin is utilized in cancer immunotherapy treatment solutions.

Funding Insights of Iovance Biotherapeutics

  • Total Rounds 11
  • Last Round Post-IPO β€” $100M
  • First Round $500,000

    (Sep 2010)

  • Investors Count 3

Latest 10 of 11 funding rounds of Iovance Biotherapeutics with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Jun 2016$100MPost-IPO––
–
Jun 2016$100MPost-IPO––
Jun 2016–Post-IPO––
Nov 2014$23.29MPost-IPO––
–
Nov 2013$23.3MPost-IPO––
May 2013$1.35MPost-IPO––
–
Jul 2011$5MPost-IPO––
–
Apr 2011$500,000Post-IPO––
–
Dec 2010$640,000Post-IPO––
–
Oct 2010$250,000Post-IPO––
–
Valuation history

3 investors in total: 3 institutional.

Investors in Iovance Biotherapeutics

Iovance Biotherapeutics has secured backing from 3 investors, including venture fund investors. Prominent investors backing the company include Orbimed, Frazier Healthcare Partners and Perceptive Advisors.

All
Venture Fund
InvestorDescriptionFounded YearDomainLocation
Healthcare sector private equity investments are managed by the firm.
1991frazierhealthcare.comSeattle, United States
Investments are made by OrbiMed in global healthcare innovations across biopharmaceuticals and related fields.
1989orbimed.comNew York, United States
Health-tech companies are targeted for venture capital investments.
1999perceptivelife.comNew York, United States
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Investor details for Iovance Biotherapeutics

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People of Iovance Biotherapeutics

90 people are tracked at Iovance Biotherapeutics (51 in leadership, 6 in board & advisors, 33 in team); the tracked headcount is 838.

NameRoleGroup
Robert T Brooke
Founder & CEOLeadership
Anthonius Kley
Associate Director Facilities EngineeringLeadership
Katie Benson
Senior Director, Global Customer Engagement & Strategic AlliancesLeadership
Howard B. Johnson
Chief Business OfficerLeadership
Igor Bilinsky
COOLeadership
Toby S.
Director; Global Channel ManagementLeadership
Gurinder Bhatia
VP Of Infrastructure & OperationsLeadership
Balaji Hariharan
Director Infrastructure OperationsLeadership
Amit Joshi
Senior Director, Strategic SourcingLeadership
Dan Kirby
Chief Commercial Officer (cco)Leadership
Minjie Feng
Senior DirectorLeadership
Morgan Landes
Director, Life Cycle Program ManagementLeadership
Brian Shew
SVP, Head of Digital & Information TechnologyLeadership
Leah Robinson
Director, Logistics And PlanningLeadership
Katrina Bezak
Senior Director, Commercial OperationsLeadership
Rana Fiaz M.d.
Executive DirectorLeadership
Bill Hershfield
Head Of Market Access Operations, Distribution And PricingLeadership
Frederick G. Vogt
Interim CEO, President & General CounselLeadership
Allison Marotta
Director, Supply ChainLeadership
Jim Meyer
Vice President Global CommercialLeadership

70 more people are available in the full profile.

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IPO & Listings of Iovance Biotherapeutics

Iovance Biotherapeutics is a publicly listed company on the NASDAQ with ticker symbol IOVA in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

  • IPO date27 May 2010
  • Listed onNASDAQ: IOVA
  • Listed entityIovance Biotherapeutics, Inc.
  • Exchange sectorHealth technology
  • ISINUS4622601007
  • Share price$14.62 (+9.84% on the day) · 2026-10-09
  • Market capitalisation$6.62B
  • EPS (diluted, trailing year)$-0.72
  • Volume (last session)16,990,348

Financials of Iovance Biotherapeutics

Exchange-reported annual figures
YearRevenueNet incomeEBITDA
2025$263.5M-$391.0M-$350.9M
2024$164.1M-$372.2M-$351.7M
2023$1.2M-$444.0M-$427.4M
2022–-$395.9M-$377.7M
2021–-$342.2M-$328.7M
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Detailed financial statements for Iovance Biotherapeutics

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Investments & Acquisitions by Iovance Biotherapeutics

Iovance Biotherapeutics has strategically engaged in corporate development activities, having acquired 1 company. Notable acquisitions include Proleukin.

Acquisitions
Company NameDescriptionDomainLocationFoundedAcquiredAmount
Information on cancer drugs is provided via an online platform.
proleukin.comYardley, United States1998Jan 2023β€’β€’β€’β€’
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Complete acquisition details for Iovance Biotherapeutics

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Timeline of Iovance Biotherapeutics

5 dated milestones of Iovance Biotherapeutics across 16 years, from founding to its latest funding, stage changes and deals.

  1. Founded Iovance Biotherapeutics is founded.
  2. IPO Lists on the stock exchange (IPO).
  3. Funding First funding round of $500K.
  4. Funding Latest funding round, Post-IPO, of $100.0M.
  5. Acquisition Acquires Proleukin.

Competitors of Iovance Biotherapeutics

Iovance Biotherapeutics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Jazz Pharmaceuticals, Revolution Medicines, Blueprint Medicines, Syndax and C4 Therapeutics, among others.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
jazzpharma.com2003Dublin, Ireland$265M2,800
Novel biopharmaceutical medicines are developed for unmet medical needs.
revmed.com2014Redwood, United States$326.29M181
Cancer therapies are developed using selective pathway inhibitors.
blueprintmedicines.com2008Cambridge, United States$115M201
Selective kinase inhibitors are developed for genomically defined cancers.
syndax.com2005Waltham, United States$198.29M107
Targeted therapies for cancer treatment are developed.
c4therapeutics.com2016Cambridge, United States$223M121
Small-molecule drugs for cancer treatment are developed via Degronimid platform.
erasca.com2018San Diego, United States$300M120
Small molecule therapeutics for cancer treatment are developed.
mereobiopharma.com2015London, United Kingdom$119M56
Therapeutics for cancer and rare diseases are developed.
aviditybiosciences.com2012San Diego, United States$142.54M253
Antibody-siRNA complexes are developed for cancer treatment.
argenx.com2008Ghent, Belgium$61.9M355
Antibody-based drugs are developed for autoimmune diseases and cancer treatment.
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Detailed competitors of Iovance Biotherapeutics

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Web traffic of Iovance Biotherapeutics

The website of Iovance Biotherapeutics (iovance.com) receives about 16.2K visits a month and ranks #1,264,131 among all websites worldwide, #1,606 in Biotechnology and Pharmaceuticals.

  • Monthly visits
    16.2K

    ▼ 19.8% vs previous month

  • Unique visitors
    9K

    per month

  • Global rank
    #1,264,131

    among all websites

  • Category rank
    #1,606

    Health · Biotechnology and Pharmaceuticals

Similar websites

Websites whose visitors overlap most with Iovance Biotherapeutics. Affinity shows how closely the audiences match.

WebsiteDomainAudience affinityMonthly visitsGlobal rankProfile
maxcyte.com
100%
11.2K#1,958,980View details
fiercebiotech.com
81%
858.3K#81,022View details
regmednet.com
regmednet.com
74%
–#1,456,222–
lilly.com
60%
4.9M#13,252View details
drugs.com
drugs.com
60%
–#3,085–
β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’.comβ€’β€’%β€’.β€’M#‒‒‒‒‒–
β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’.comβ€’β€’%β€’.β€’M#‒‒‒‒‒–
β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’β€’.comβ€’β€’%β€’.β€’M#‒‒‒‒‒–
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All 8 similar websites and full traffic analytics for Iovance Biotherapeutics

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Verified entity values are shown only after access is granted.

Latest news on Iovance Biotherapeutics

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Similar companies to Iovance Biotherapeutics

10 companies that operate in the same segment as Iovance Biotherapeutics (Cell Therapy), ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
CAR T-cell and T-cell receptor immunotherapies for cancer are developed.
2013Seattle, Washington, United StatesUSD 316.67 M–520
CAR-T and TIL immunotherapies for solid tumors are developed.
2018San Francisco, California, United StatesUSD 493 MUSD 36 K300
T-cell-based immunotherapies for cancer treatment are developed.
2000Tubingen, Baden-wurttemberg, GermanyUSD 236.4 MUSD 54.47 M423
Engineered T-cell immunotherapies are developed for cancer and auto-immune diseases.
2015London, England, United KingdomUSD 181.37 MUSD 75.56 M647
Smart surgical devices for spinal surgery are developed.
1997San Diego, California, United StatesUSD 54.1 M––
Genetically engineered cell therapies are developed for multiple disorders.
2018Seattle, Washington, United StatesUSD 821 M–194
Provider of bio-artificial pancreas for Type 1 Diabetes treatment
2015Cambridge, Massachusetts, United StatesUSD 158 M–58
T-cell and antibody-based therapeutics are developed via single-cell sequencing platforms.
2011San Francisco, California, United StatesUSD 36.13 M–36
Developer of immune cell therapies
2019San Francisco, California, United StatesUSD 631.16 M–178
Cue Biopharma is focused on developing immunotherapy solutions.
2015Cambridge, Massachusetts, United StatesUSD 10 MUSD 27.47 M41
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Frequently Asked Questions about Iovance Biotherapeutics

Iovance Biotherapeutics was founded in 2007 and raised its 1st funding round 3 years after it was founded.

Iovance Biotherapeutics is headquartered in San Carlos, United States. It is registered at San Carlos, California, United States.

Robert T Brooke is the current CEO of Iovance Biotherapeutics. They have also founded this company.

Iovance Biotherapeutics has 838 employees.

Annual revenue of Iovance Biotherapeutics is $263.5M as on Dec 31, 2025.

Iovance Biotherapeutics is engaged in pioneering cancer treatment by leveraging the human immune system. The company is dedicated to developing Tumor Infiltrating Lymphocyte (TIL) therapies and Peripheral Blood Lymphocyte (PBL) therapies for solid tumors and blood cancers. Solutions are personalized to target diverse cancer cells unique to each patient. Research and clinical trials are conducted across multiple advanced cancer types, including melanoma, NSCLC, and endometrial cancer. Manufacturing is supported by a state-of-the-art facility in Philadelphia. The focus is placed on next-generation approaches to enhance cancer treatment outcomes.

Iovance Biotherapeutics's top competitors include Jazz Pharmaceuticals, C4 Therapeutics and argenx.

Iovance Biotherapeutics offers Amtagvi and Proleukin.

Yes, Iovance Biotherapeutics is publicly traded on NASDAQ under the ticker symbol IOVA.

Iovance Biotherapeutics has made 1 acquisition, including Proleukin.

Iovance Biotherapeutics has 3 investors. Key investors include Orbimed, Frazier Healthcare Partners, and Perceptive Advisors.

Iovance Biotherapeutics operates through Iovance Biotherapeutics, Inc..

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