OptiNose

Morrisville, United States Founded: 2000 • Age: 26 yrs Listed Acquired By Paratek Pharma
Developer of smart devices for nasal drug delivery

About OptiNose

OptiNose is a company based in Morrisville (United States) founded in 2000 was acquired by Paratek Pharma in March 2025. OptiNose has raised $120.5 million across 10 funding rounds from investors including Fidelity Investments, Paratek Pharma and bpcruk. The company has 132 employees. OptiNose offers products and services including XHANCE, ONZETRA, and Xsail. OptiNose operates in a competitive market with competitors including MannKind Corp, Impel NeuroPharma, Alexza, Qnovia and Iconovo, among others.

  • Headquarter Morrisville, United States
  • Employees 132
  • Stage Public
  • Sectors
    Healthcare
  • Website optinose.com
  • Social LinkedIn
  • Acquired by Paratek Pharma (Mar 2025)
  • Legal Name Optinose Us, Inc.
Key Metrics
  • Annual Revenue
    $76.28 M (USD)
    2
    as on Dec 31, 2022
  • Total Equity Funding
    $120.5M (USD)

    in 10 rounds

  • Latest Funding Round
    $4.68M (USD), Post-IPO

    May 2024

  • Investors
  • Employee Count
    132
  • Acquired by

Products & Services of OptiNose

OptiNose offers a comprehensive portfolio of products and services, including XHANCE, ONZETRA, and Xsail.

XHANCE
Nasal Spray

Delivers steroid for treating nasal inflammation in ENT conditions.

ONZETRA
Migraine Treatment

Exhalation delivery system for migraine relief medication.

Xsail
Delivery Device

Nasal device for effective medication administration in allergies.

Funding Insights of OptiNose

OptiNose has successfully raised a total of $120.5M across 10 strategic funding rounds. The most recent funding activity was a Post-IPO round of $4.68 million completed in May 2024. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $120.5M
  • Total Rounds 10
  • Last Round Post-IPO — $4.68M
  • First Round $48.5M

    (Jun 2010)

  • Investors Count 6

All 10 funding rounds of OptiNose with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
May 2024$4.68MPost-IPO––
–
Nov 2021$4MPost-IPO––
–
Aug 2020$250,000Post-IPO––
–
Sep 2019$5.45MPost-IPO––
–
Sep 2019$150MDebt – Conventional––
Dec 2017–Post-IPO––
Apr 2017$37MSeries D–Fidelity Investments
Oct 2015$35MSeries D–WFD Ventures, Entrepreneurs Fund
–
Aug 2014–Series C––
Jun 2010$48.5MSeries B––
Valuation history

7 investors in total: 7 institutional.

Investors in OptiNose

OptiNose has secured backing from 7 investors, including institutional and venture fund investors. Prominent investors backing the company include Fidelity Investments, Paratek Pharma and bpcruk.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Global private equity investments are managed by the firm.
–athyrium.comNew York, United States
Tech & life science focused stage agnostic VC firm investing primarily in Western Europe
–entrepreneursfund.comLondon, United Kingdom
-
–wfdventures.com-
Provider of marketing services to biopharma sector
2016bpcruk.comUnited Kingdom
Provider of brokerage accounts, retirement planning, wealth management, and trading platforms
1946fidelity.comBoston, United States
Private equity investments are focused on the United States market.
–avistacap.comNew York, United States
Therapeutics for antimicrobial resistant infections are developed.
1996paratekpharma.comBoston, United States
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Investor details for OptiNose

The complete investor list, round-by-round participation and investor portfolios require an active premium plan.

  • Complete investor list
  • Round participation
  • Investor portfolios
  • Co-investor network

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People of OptiNose

25 people are tracked at OptiNose (13 in leadership, 5 in board & advisors, 7 in team); the tracked headcount is 132.

NameRoleGroup
Lee Lockard
Executive Director Market-access (clt Member)Leadership
Jilliane Frederick
Associate Director, Regulatory And Quality OperationsLeadership
Ramy A. Mahmoud
CEO & DirectorLeadership
Mike Marino
Chief Legal OfficerLeadership
Karen E. Brophy
Chief Human Resources OfficerLeadership
Jonathan Neely
VP, Investor Relations, & Business DevelopmentLeadership
Deann L. Kenehan
Director, Thought Leader EngagementLeadership
Cindy Lehrer
Senior Director Of Human ResourcesLeadership
Stephen King
Sr. Director ITLeadership
Renee Marotta
Vice President MarketingLeadership
Bogdan Butoi
Vice President Of Information TechnologyLeadership
Ben Porter
Regional Business DirectorLeadership
Pamela Gray
Sr. Director, QualityLeadership
R. John Fletcher
DirectorBoard & advisors
Kyle Dempsey
DirectorBoard & advisors
Wilhelmus Groenhuysen
DirectorBoard & advisors
Catherine E. Owen
DirectorBoard & advisors
Tomas J. Heyman
DirectorBoard & advisors
Joe Perrin
Manager, Financial A Information SystemsTeam
Ramona Lloyd
SVP, Regulatory & QualityTeam

5 more people are available in the full profile.

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Complete people profiles for OptiNose

Full employee and board profiles, team structure, tenure and professional contact details require an active premium plan.

  • Full employee list
  • Team structure
  • Board tenure
  • Professional contacts

Verified entity values are shown only after access is granted.

Timeline of OptiNose

5 dated milestones of OptiNose across 25 years, from founding to its latest funding, stage changes and deals.

  1. Founded OptiNose is founded.
  2. Funding First funding round of $48.5M.
  3. IPO Lists on the stock exchange (IPO).
  4. Funding Latest funding round, Post-IPO, of $4.7M.
  5. Exit Acquired by Paratek Pharma.

Competitors of OptiNose

OptiNose operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as MannKind Corp, Impel NeuroPharma, Alexza, Qnovia and Iconovo, among others.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
mannkindcorp.com1991Los Angeles, United States$50M322
Developer of small-molecule drugs
impelnp.com2008Seattle, United States$126.83M158
Intranasal delivery technology for CNS diseases is developed.
alexza.com2000Mountain View, United States$97M72
Developer of products for the treatment of acute and intermittent conditions
qnovia.com2018Richmond, United States$38.12M–
Inhaled drug delivery devices are developed for pharmaceuticals.
iconovo.se2013Lund, Sweden$3.56M–
Inhalation devices for medical applications are developed by Iconovo.
aerami.com2010Durham, United States$151.1M–
Therapeutics for cardiopulmonary diseases are developed using inhaled therapies.
nobhilltherapeutics.com2016Albuquerque, United States$3.67M–
Dry powder nebulizer is developed for targeted lung drug delivery.
beyondair.net2011Garden, United States––
Developer of device for treating respiratory conditions
nebuflow.com2019Glasgow, United Kingdom$7.97M–
Aerosol delivery platform technology is developed for medical applications.
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Detailed competitors of OptiNose

The full competitor set, operating metrics and side-by-side benchmarks require an active premium plan.

  • Full competitor set
  • Operating metrics
  • Benchmarks
  • Competitive positioning

Verified entity values are shown only after access is granted.

Web traffic of OptiNose

The website of OptiNose (optinose.com) receives about 5.1K visits a month.

  • Monthly visits
    5.1K

    ▼ 10.4% vs previous month

Latest news on Optinose

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Complete news archive for OptiNose

Full article history, source details, and older brand coverage require an active premium plan.

  • Full article archive
  • Source and publication date
  • Older coverage
  • Brand-specific news history

Verified entity values are shown only after access is granted.

Similar companies to OptiNose

10 companies that operate in the same segment as OptiNose (Biopharma Outsourcing & Drug Delivery), ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
Developer of integrated contract research development and manufacturing services
2007Bengaluru, Karnataka, IndiaUSD 35.74 MUSD 226.38 M1,820
Drug discovery and development services are provided to biopharma sector.
1993Hamburg, Hamburg, GermanyUSD 25 MUSD 926.33 M4,830
Drug discovery and development services for small molecules are provided.
2003Beijing, ChinaUSD 320 M–476
Suite solutions are provided for payers and healthcare providers.
1998Princeton, New Jersey, United StatesUSD 255.15 MUSD 374.1 M4,490
Wearable insulin infusion systems are developed for diabetes patients.
2000Boston, Massachusetts, United StatesUSD 120.4 MUSD 2.71 B3,900
Developer of small-molecule drugs
1991Los Angeles, California, United StatesUSD 50 MUSD 348.97 M407
Pharmaceutical and biotechnology company
2005Hyderabad, Telangana, IndiaUSD 229.73 MUSD 726.15 M12,470
Pharmaceutical products for treating multiple diseases are provided.
1849New York, New York, United StatesUSD 8 MUSD 266.99 M1,770
Provider of laboratory tests for physicians
1969Burlington, Vermont, United States–USD 13.95 B70,000
India's leading healthcare products distribution platform
2018Mumbai, Maharashtra, IndiaUSD 59.67 MUSD 702.49 M4,260
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Frequently Asked Questions about OptiNose

OptiNose was founded in 2000 and raised its 1st funding round 10 years after it was founded.

OptiNose is headquartered in Morrisville, United States.

OptiNose is a funded company, having raised a total of $120.5M across 10 funding rounds to date. The company's 1st funding round was a Series B of $48.5M, raised on Jun 2010.

OptiNose has 132 employees.

Annual revenue of OptiNose is $76.28M as on Dec 31, 2022.

OptiNose is a developer of smart devices for nasal drug delivery. The drug delivery devices can be used for powder and liquid formulations. Pipeline includes candidates for chronic nasal inflammatory disease, migraine and autism.

OptiNose's top competitors include MannKind Corp, Impel NeuroPharma and Qnovia.

OptiNose offers XHANCE, ONZETRA, and Xsail.

OptiNose has 7 investors. Key investors include Fidelity Investments, Paratek Pharma, bpcruk, Athyrium Capital Management, and Avista Capital Partners.

OptiNose operates through Optinose Us, Inc..

Yes. OptiNose was acquired by Paratek Pharma in March 2025.

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