Passage Bio

Philadelphia, United States Founded: 2017 • Age: 9 yrs Listed
Gene therapies for CNS rare diseases are developed.

About Passage Bio

Passage Bio is a publicly listed company based in Philadelphia (United States) founded in 2017 by Stephen Squinto. Gene therapies for CNS rare diseases are developed. Passage Bio has raised $225.5 million across 3 funding rounds from investors including New Leaf Venture Partners, Orbimed and Frazier Healthcare Partners. The company has 60 employees. Its chief executive, as recorded, is William Chou. Its focus areas include Life Sciences, Genomics, Applied Genomics and Clinical Genomics. Its competitors include BridgeBio, Spark Therapeutics and Alnylam; 3 of its 3 listed competitors have raised funding.

Company details

Passage Bio was founded in 2017 in Philadelphia, United States, within the biotechnology sector. AAV-delivered therapeutics are developed for rare monogenic central nervous system diseases. Lead programs are directed toward GM1 gangliosidosis, frontotemporal dementia, and Krabbe disease. Operations center on advancing gene therapy solutions for these conditions, with research and development conducted in the U.S. geographic area.

  • Headquarters Philadelphia, United States
  • Employees 60
  • Founders Stephen Squinto
  • Stage Public
  • Sectors
    Healthcare
  • Website category Health · Biotechnology and Pharmaceuticals
  • Email
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  • Website passagebio.com
  • Social LinkedIn
  • Legal Name Passage Bio, Inc.
Key Metrics
  • Net Profit
    -$45.52 M (USD)
    29.71
    as on Dec 31, 2025
  • EBITDA
    -$42.42 M (USD)
    31.67
    as on Dec 31, 2025
  • Total Equity Funding
    $225.5M (USD)

    in 3 rounds

  • Latest Funding Round
    $50M (USD), Post-IPO

    Sep 2021

  • Investors
  • Employee Count
    60

Funding Insights of Passage Bio

Passage Bio has successfully raised a total of $225.5M across 3 strategic funding rounds. The most recent funding activity was a Post-IPO round of $50 million completed in September 2021. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $225.5M
  • Total Rounds 3
  • Last Round Post-IPO β€” $50M
  • First Round $115.5M

    (Feb 2019)

  • Investors Count 11

All 3 funding rounds of Passage Bio with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Sep 2021$50MPost-IPO––
Sep 2019$110MSeries B–Access Biotechnology
Feb 2019$115.5MSeries A–Orbimed
Valuation history

11 investors in total: 11 institutional.

Investors in Passage Bio

Passage Bio has secured backing from 11 investors, including venture fund and institutional investors. Prominent investors backing the company include New Leaf Venture Partners, Orbimed and Frazier Healthcare Partners.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Venture capital firm managing investments in biotechnology and pharmaceuticals since 1999.
versantventures.com
Investments are made by OrbiMed in global healthcare innovations across biopharmaceuticals and related fields.
1989orbimed.comNew York, United States
Healthcare sector private equity investments are managed by the firm.
1991frazierhealthcare.comSeattle, United States
Biotech startups are funded by this venture capital firm.
boxercap.comSan Diego, United States
Stage-agnostic investments in US life sciences are managed.
2005nlvpartners.comNew York, United States
Venture capital and private equity firm
vivocapital.comPalo Alto, United States
Private equity fund focused on the biotechnology sector
logoscapital.comSan Francisco, United States
lillyasiaventures.com
Investment firm managing mid and large cap U.S. equities portfolios via fundamental research.
1995highlinecap.comNew York, United States
Manages hedge funds with long/short equity and real estate strategies for investors.
2004spherafund.comTel Aviv, Israel
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Investor details for Passage Bio

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People of Passage Bio

30 people are tracked at Passage Bio (20 in leadership, 6 in board & advisors, 4 in team); the tracked headcount is 60.

NameRoleGroup
Stephen Squinto
Co-FounderLeadership
William Chou
CEOLeadership
Jasmine Li
Executive Director Of Analytical Development & Quality ControlLeadership
Paulette Triglia
Executive Director, Clinical OperationsLeadership
Jiwen Zhang
VP, Regulatory AffairsLeadership
Sue Browne
VP, BiologyLeadership
Tiffini Voss
VP, Clinical DevelopmentLeadership
Stuart Henderson
VP, Corporate Development & Investor RelationsLeadership
James M. Wilson
Chief Scientific AdvisorLeadership
Samiah Al-Zaidy
VP, Clinical DevelopmentLeadership
Kathleen Borthwick
VP, Financial Planning & AnalysisLeadership
Susan Browne
Senior Vice President, Research & DevelopmentLeadership
Glen Kerker II
Director, Regulatory OperationsLeadership
Steve Krausert
Vice President, Supply Chain & PlanningLeadership
Dave Bottari
Head Of Quality Assurance - Executive DirectorLeadership
Sharath Vallabhajosyula
Associate Director, Biomarker OperationsLeadership
Joshua Benton
Director Of Manufacturing Technical OperationsLeadership
Pamela H.
Vice President Clinical OperationsLeadership
Karl Whitney
Senior Vice President, Global Regulatory AffairsLeadership
Chelsea Difebbo Ortiz
Executive Director, Patient AdvocacyLeadership

10 more people are available in the full profile.

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IPO & Listings of Passage Bio

Passage Bio is a publicly listed company on the NASDAQ with ticker symbol PASG in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

  • IPO date28 Feb 2020
  • Listed onNASDAQ: PASG
  • Listed entityPassage Bio, Inc.
  • Exchange sectorHealth technology
  • ISINUS7027122099
  • Share price$3.64 (-20% on the day) · 2026-10-13
  • Market capitalisation$11.7M
  • EPS (diluted, trailing year)$-11.31
  • Volume (last session)14,219

Financials of Passage Bio

Exchange-reported annual figures
YearRevenueNet incomeEBITDA
2025-$45.5M-$42.4M
2024-$64.8M-$62.1M
2023-$102.1M-$96.4M
2022-$136.1M-$125.6M
2021-$185.4M-$176.2M
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Detailed financial statements for Passage Bio

Statement rows, ratios, five-year trends and downloadable financials of the group companies require an active premium plan.

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Timeline of Passage Bio

4 dated milestones of Passage Bio across 4 years, from founding to its latest funding, stage changes and deals.

  1. Founded Passage Bio is founded.
  2. Funding First funding round of $115.5M.
  3. IPO Lists on the stock exchange (IPO).
  4. Funding Latest funding round, Post-IPO, of $50.0M.

Competitors of Passage Bio

Passage Bio has 3 listed competitors in our database, 3 of them funded. They include BridgeBio, Spark Therapeutics and Alnylam.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
bridgebio.com2015Palo Alto, United States$434.2M
Therapeutics for genetic diseases are developed through targeted interventions.
sparktx.com2013Philadelphia, United States$82.8M822
Gene therapies for rare diseases including retinal dystrophies are developed.
alnylam.com2002Cambridge, United States$17M2,100
RNA interference-based therapeutics are developed for multiple disorders.
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Detailed competitors of Passage Bio

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Web traffic of Passage Bio

The website of Passage Bio (passagebio.com) receives about 6.9K visits a month and ranks #3,738,748 among all websites worldwide, #4,786 in Biotechnology and Pharmaceuticals.

  • Monthly visits
    6.9K

    ▲ 41.3% vs previous month

  • Unique visitors
    2K

    per month

  • Global rank
    #3,738,748

    among all websites

  • Category rank
    #4,786

    Health · Biotechnology and Pharmaceuticals

Top companies in Genomics & Gene Therapy Platforms

3 companies that operate in the same segment as Passage Bio (Genomics & Gene Therapy Platforms) in United States, ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Digital sequencing technology for cancer detection is developed.
2012Redwood City, California, United StatesUSD 557.5 MUSD 982.02 M4,867
Circulating tumor DNA is screened for early cancer detection.
2016Menlo Park, California, United StatesUSD 2 BUSD 147.17 M1,141
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Related news about Passage Bio

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Frequently Asked Questions about Passage Bio

Passage Bio was founded in 2017 and raised its 1st funding round 2 years after it was founded.

Passage Bio is headquartered in Philadelphia, United States. It is registered at Philadelphia, Pennsylvania, United States.

William Chou is the CEO of Passage Bio, as recorded in our data.

Passage Bio is a funded company, having raised a total of $225.5M across 3 funding rounds to date. The company's 1st funding round was a Series A of $115.5M, raised on Feb 2019.

Passage Bio has 60 employees.

Passage Bio was founded in 2017 in Philadelphia, United States, within the biotechnology sector. AAV-delivered therapeutics are developed for rare monogenic central nervous system diseases. Lead programs are directed toward GM1 gangliosidosis, frontotemporal dementia, and Krabbe disease. Operations center on advancing gene therapy solutions for these conditions, with research and development conducted in the U.S. geographic area.

Passage Bio's top competitors include Spark Therapeutics, BridgeBio and Alnylam.

Yes, Passage Bio is publicly traded on NASDAQ under the ticker symbol PASG.

Passage Bio has 11 investors. Key investors include New Leaf Venture Partners, Orbimed, Frazier Healthcare Partners, Versant Ventures, and Lilly Asia Ventures.

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