Primmune

San Diego, United States Founded: 2017 • Age: 9 yrs
Immunotherapies for cancer are developed using TLR7 agonists.

About Primmune

Primmune is a company based in San Diego (United States) founded in 2017 by Jim Appleman and Paulo Rangel. It operates as a HealthTech. Primmune has raised $60.03 million across 8 funding rounds from investors including McDermott International, Bioqube Ventures and CAM Capital. Primmune offers products and services including PRTX007. Primmune operates in a competitive market with competitors including TScan Therapeutics, Lyell Immunopharma, Hummingbird Bioscience, GigaGen and Shattuck Labs, among others.

  • Headquarter San Diego, United States
  • Founders Jim Appleman, Paulo Rangel
  • Sectors
    Healthcare
  • Email
    ***********
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Primmune Therapeutics, Inc.
Operational Areas
Healthcare → Pharmaceuticals & Therapeutics
Healthcare → Healthcare Products & Supplies
Key Metrics
  • Annual Revenue
  • Net Profit
  • EBITDA
  • Total Equity Funding
    $60.03 M (USD)

    in 8 rounds

  • Latest Funding Round
    $8.6 M (USD), Series B

    Jan 26, 2026

  • Investors
  • Employee Count
    Employee Count
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Products & Services of Primmune

Primmune offers a comprehensive portfolio of products and services, including PRTX007. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.

Primary

PRTX007 is developed as a TLR7 agonist therapy.

People of Primmune
Headcount 1-10
Employee Profiles 8
Board Members and Advisors 9
Employee Profiles
People
James Appleman
SVP, R&D & CSO Co-Founder, Director
People
Richard Daniels
Chief Operating Officer
People
Charles McDermott
Chairman, President & CEO
People
Paulo Rangel
Chief Business Officer & Co-Founder

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Board Members and Advisors
people
Amir Nashat
Director
people
Todd Harris
Director
people
Elina Zuniga
Scientific Advisor
people
Sheldon Morris
Clinical Advisor

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Funding Insights of Primmune

Primmune has successfully raised a total of $60.03M across 8 strategic funding rounds. The most recent funding activity was a Series B round of $8.6 million completed in January 2026. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 8
  • Last Round Series B — $8.6M
  • First Round

    (18 Oct 2017)

  • Investors Count 9
Date Amount Transaction Name Valuation Lead Investors Investors
Jan, 2026 Amount Series B - Primmune Valuation

investors

Nov, 2021 Amount Series A - Primmune Valuation

investors

Jan, 2021 Amount Series A - Primmune Valuation Bioqube Ventures
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Investors in Primmune

Primmune has secured backing from 9 investors, including venture fund, institutional, and angel investors. Prominent investors backing the company include McDermott International, Bioqube Ventures and CAM Capital. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Angel
Investor Description Founded Year Domain Location
Life sciences investments are managed by Bioqube Ventures in Europe and the US to advance therapeutic assets and technologies.
Founded Year Domain Location
US focused venture capital firm
Founded Year Domain Location
Venture capital funding is provided by Samsara BioCapital in California.
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by Primmune

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016

Financial Statements - Primmune

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Primmune Comparisons

Employees
+
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Competitors of Primmune

Primmune operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as TScan Therapeutics, Lyell Immunopharma, Hummingbird Bioscience, GigaGen and Shattuck Labs, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
T cell-based treatments for immunological and oncological disorders are developed.
domain founded_year HQ Location
CAR-T and TIL immunotherapies for solid tumors are developed.
domain founded_year HQ Location
Antibody drugs for cancer treatment are developed.
domain founded_year HQ Location
T-cell and antibody-based therapeutics are developed via single-cell sequencing platforms.
domain founded_year HQ Location
An immunotherapy platform for oncology and other diseases is developed.
domain founded_year HQ Location
Viral immunotherapies are developed for cancer treatment.
Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

Frequently Asked Questions about Primmune

When was Primmune founded?

Primmune was founded in 2017.

Where is Primmune located?

Primmune is headquartered in San Diego, United States. It is registered at San Diego, California, United States.

Who is the current CEO of Primmune?

Paulo Rangel is the current CEO of Primmune. They have also founded this company.

Is Primmune a funded company?

Primmune is a funded company, having raised a total of $60.03M across 8 funding rounds to date. The company's 1st funding round was a Series A of $4M, raised on Oct 18, 2017.

What does Primmune do?

Primmune is engaged in the development of innovative therapies targeting cancer and viral infections through the activation of innate immunity. The company specializes in toll-like receptor 7 (TLR7) agonists, with its lead candidate PRTX007 being advanced for clinical trials in HPV-caused oropharyngeal cancer and hepatocellular carcinoma. Solutions are designed to stimulate plasmacytoid dendritic cells (pDCs) for systemic immune responses while minimizing proinflammatory side effects. Operations are centered in the healthcare and biotechnology sectors, addressing significant global health challenges.

Who are the top competitors of Primmune?

Primmune's top competitors include Hummingbird Bioscience, Lyell Immunopharma and GigaGen.

What products or services does Primmune offer?

Primmune offers PRTX007.

Who are Primmune's investors?

Primmune has 9 investors. Key investors include McDermott International, Bioqube Ventures, CAM Capital, Polaris Partners, and Samsara BioCapital.

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