Xilio Therapeutics

Waltham, United States Founded: 2016 • Age: 10 yrs
Tumor-selective immunotherapies for cancer treatment are developed.

About Xilio Therapeutics

Xilio Therapeutics is a company based in Waltham (United States) founded in 2016.. Xilio Therapeutics has raised $233 million across 5 funding rounds from investors including AbbVie, Takeda Pharmaceuticals and Ipsen. The company has 64 employees as of December 31, 2024. Xilio Therapeutics offers products and services including Vilastobart, XTX301, and XTX501. Xilio Therapeutics operates in a competitive market with competitors including Zymeworks, Harbour BioMed, Ambrx, Lassen Therapeutics and Leap Therapeutics, among others.

  • Headquarter Waltham, United States
  • Employees 64 as on 31 Dec, 2024
  • Stage Public
  • Sectors
    Healthcare
  • Phone
    *********
  • Website
    *********
  • Social
    *********
  • Legal Name Xilio Therapeutics, Inc.
Operational Areas
Healthcare → Pharmaceuticals & Therapeutics
Healthcare → Healthcare Products & Supplies
Key Metrics
  • Annual Revenue
    $6.34 M
    0
    as on Dec 31, 2024
  • Net Profit
    $-58.24 M
    23.77
    as on Dec 31, 2024
  • EBITDA
    $-58 M
    24.9
    as on Dec 31, 2024
  • Total Equity Funding
    $233 M (USD)

    in 5 rounds

  • Latest Funding Round
    $10 M (USD), Post-IPO

    Feb 12, 2025

  • Investors
    AbbVie

    & 15 more

  • Employee Count
    64

    as on Dec 31, 2024

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IPO & Listings of Xilio Therapeutics

Xilio Therapeutics is a publicly listed company on the NASDAQ with ticker symbol XLO in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

Exchange: NASDAQ · Ticker: XLO . Sector: Health technology · USA

Products & Services of Xilio Therapeutics

Xilio Therapeutics offers a comprehensive portfolio of products and services, including Vilastobart, XTX301, and XTX501. The company's diverse product and service offerings are designed to meet the evolving needs of its customers, address market demands, and provide comprehensive solutions that drive value creation and customer satisfaction across various segments and use cases.

Primary

Targets CTLA-4 for selective tumor immunotherapy in cancer treatment.

Delivers IL-12 to enhance immune response against tumors.

Focuses on masked T cell engagers for targeted cancer therapy.

People of Xilio Therapeutics
Headcount 50-200
Employee Profiles 38
Board Members and Advisors 17
Employee Profiles
People
Sheila Murphy
Executive Assistant To Chief Financial Officer and General Counsel
People
Rene Russo
CEO
People
Chris Frankenfield
CFO & COO
People
Uli Bialucha
Chief Scientific Officer

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Board Members and Advisors
people
Sara Bonstein
Director
people
Jason J. Luke
Scientific Advisor
people
Yuan Xu
Director
people
Christina Rossi
Director

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Funding Insights of Xilio Therapeutics

Xilio Therapeutics has successfully raised a total of $233M across 5 strategic funding rounds. The most recent funding activity was a Post-IPO round of $10 million completed in February 2025. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding
  • Total Rounds 5
  • Last Round Post-IPO — $10.0M
  • First Round

    (12 Oct 2016)

  • Investors Count 16
Date Amount Transaction Name Valuation Lead Investors Investors
Feb, 2025 Amount Post-IPO - Xilio Therapeutics Valuation

investors

Jan, 2021 Amount Series C - Xilio Therapeutics Valuation Rock Springs Capital
Mar, 2020 Amount Series B - Xilio Therapeutics Valuation Takeda Ventures
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Investors in Xilio Therapeutics

Xilio Therapeutics has secured backing from 16 investors, including institutional and venture fund investors. Prominent investors backing the company include AbbVie, Takeda Pharmaceuticals and Ipsen. This diverse investor base provides strategic capital, industry expertise, and valuable network connections that support the company's growth initiatives, market expansion, and long-term value creation.

All
Venture Fund
Institutional
Investor Description Founded Year Domain Location
Early-stage and late-stage biotech and finance companies are funded.
Founded Year Domain Location
Healthcare ecosystem is supported through investment and innovation by Deerfield.
Founded Year Domain Location
Venture capital firm investing in life science and biotechnology sectors
Founded Year Domain Location
Investor Description Founded Year Domain Location
Single family office of Amitabh Bachchan, founder of Amitabh Bachchan Corporation or AB CORP
Founded Year Domain Location
Startup ecosystems are ignited through strategic investments by Signite Partners.
Founded Year Domain Location
Venture capital is directed toward companies in multiple sectors.
Founded Year Domain Location
Venture capital is invested in cybersecurity, fintech, and AI startups.
Founded Year Domain Location

Investments & Acquisitions by Xilio Therapeutics

Investments
Company Name Description Domain Location Founded Year Amount
Bionic investment advisor platform
2016
Fine Asian gourmet food is offered by an internet-first restaurant.
2016
Physical e-commerce kiosks are deployed for rural purchases in Indonesia.
2014
Fine Asian gourmet food is offered by an internet-first restaurant.
2016

Financial Statements - Xilio Therapeutics

Tata Steel revenue growth over time
Tata Steel profit and loss trends over time
Date Amount Transaction Name Valuation Lead Investors Investors
Jul, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Jan, 2021 Amount Post-IPO - Grab Valuation

investors

Feb, 2021 Amount Post-IPO - Grab Valuation

investors

Xilio Therapeutics Comparisons

Employees
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Competitors of Xilio Therapeutics

Xilio Therapeutics operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Zymeworks, Harbour BioMed, Ambrx, Lassen Therapeutics and Leap Therapeutics, among others. This competitive environment drives innovation, market differentiation, and strategic positioning as companies strive to capture market share and deliver value to their customers. Understanding the competitive dynamics is crucial for assessing market positioning, identifying growth opportunities, and navigating the challenges inherent in a competitive marketplace.

Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Bi-specific antibodies and antibody-drug conjugates are developed for cancer treatment.
domain founded_year HQ Location
Antibody therapeutics are developed for immunology and oncology diseases.
domain founded_year HQ Location
Antibody-drug conjugates are developed for cancers and metabolic disorders.
domain founded_year HQ Location
Biotherapeutics targeting cancer via interleukin-11 are developed.
domain founded_year HQ Location
Novel immuno-oncology therapeutics are acquired and developed for clinical advancement.
Company Name Domain Founded year HQ Location Description
domain founded_year HQ Location
Multiple services are booked via an app-based platform.
domain founded_year HQ Location
On-demand services are booked through an app-based platform.
domain founded_year HQ Location
App based platform offering on demand delivery and ride-hailing services
domain founded_year HQ Location
Operates an on-demand hyperlocal delivery app for food and groceries.

Latest news on Xilio Therapeutics

Frequently Asked Questions about Xilio Therapeutics

When was Xilio Therapeutics founded?

Xilio Therapeutics was founded in 2016.

Where is Xilio Therapeutics located?

Xilio Therapeutics is headquartered in Waltham, United States. It is registered at Waltham, Massachusetts, United States.

Who is the current CEO of Xilio Therapeutics?

Rene Russo is the current CEO of Xilio Therapeutics.

Is Xilio Therapeutics a funded company?

Xilio Therapeutics is a funded company, having raised a total of $233M across 5 funding rounds to date. The company's 1st funding round was a Series B of $100.5M, raised on Oct 12, 2016.

How many employees does Xilio Therapeutics have?

As of Dec 31, 2024, the latest employee count at Xilio Therapeutics is 64.

What is the annual revenue of Xilio Therapeutics?

Annual revenue of Xilio Therapeutics is $6.34M as on Dec 31, 2024.

What does Xilio Therapeutics do?

Xilio Therapeutics was founded in 2016 and is headquartered in Waltham, United States. Focus is placed on biotechnology, specifically the development of immunotherapies for cancer. Proprietary technology is utilized to engineer therapies activated selectively within tumors, minimizing systemic toxicity. Key candidates include XTX201, an IL-2 variant that promotes immune responses in tumors, along with XTX101, XTX301, and XTX401, which exhibit antitumor effects in preclinical studies.

Who are the top competitors of Xilio Therapeutics?

Xilio Therapeutics's top competitors include Ambrx, Harbour BioMed and BioAtla.

What products or services does Xilio Therapeutics offer?

Xilio Therapeutics offers Vilastobart, XTX301, and XTX501.

Is Xilio Therapeutics publicly traded?

Yes, Xilio Therapeutics is publicly traded on NASDAQ under the ticker symbol XLO.

Who are Xilio Therapeutics's investors?

Xilio Therapeutics has 16 investors. Key investors include AbbVie, Takeda Pharmaceuticals, Ipsen, RA Capital, and Atlas Venture.

What is Xilio Therapeutics's ticker symbol?

The ticker symbol of Xilio Therapeutics is XLO on NASDAQ.

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