Generation Bio

Cambridge, United States Founded: 2016 • Age: 10 yrs Listed Acquired By XOMA Corporation
Gene therapies for rare liver and eye diseases are developed.

About Generation Bio

Generation Bio is a company based in Cambridge (United States) founded in 2016 by Phillip Samayoa and Mark Angelino was acquired by XOMA Corporation in December 2025. Generation Bio has raised $236.47 million across 3 funding rounds from investors including Fidelity Investments, T. Rowe Price and Farallon Capital Management. The company has 115 employees. Generation Bio offers products and services including ctLNP-siRNA. Generation Bio operates in a competitive market with competitors including Moderna, BridgeBio, Spark Therapeutics, Alnylam and ATAI, among others.

  • Headquarter Cambridge, United States
  • Employees 115
  • Founders Phillip Samayoa, Mark Angelino
  • Stage Public
  • Sectors
    Healthcare
  • Website category Health · Biotechnology and Pharmaceuticals
  • Email
    β€’β€’β€’β€’β€’β€’β€’β€’
  • Website generationbio.com
  • Social LinkedIn X
  • Acquired by XOMA Corporation (Dec 2025)
  • Legal Name Generation Bio Co.
Key Metrics
  • Annual Revenue
    $19.89 M (USD)
    236.92
    as on Dec 31, 2024
  • Net Profit
    -$131.67 M (USD)
    -3.99
    as on Dec 31, 2024
  • EBITDA
    -$73.41 M (USD)
    41.87
    as on Dec 31, 2024
  • Total Equity Funding
    $236.47M (USD)

    in 3 rounds

  • Latest Funding Round
    $111.47M (USD), Series C

    Jan 2020

  • Investors
  • Employee Count
    115
  • Acquired by

Products & Services of Generation Bio

Generation Bio offers a comprehensive portfolio of products and services, including ctLNP-siRNA.

ctLNP-siRNA
Therapeutic Technology

Delivers siRNA to T cells for treating autoimmune diseases

Funding Insights of Generation Bio

Generation Bio has successfully raised a total of $236.47M across 3 strategic funding rounds. The most recent funding activity was a Series C round of $111.47 million completed in January 2020. This substantial capital infusion reflects strong investor confidence in the company's business model, growth potential, and market opportunities. The funding enables strategic expansion, product development, market penetration, and operational scaling to drive long-term value creation and competitive advantage.

  • Total Funding $236.47M
  • Total Rounds 3
  • Last Round Series C β€” $111.47M
  • First Round $25M

    (Jan 2018)

  • Investors Count 10

All 3 funding rounds of Generation Bio with amounts and investors; the two latest post-money valuations are shown, the rest are part of the premium plan.

DateAmountTransaction NameValuationLead InvestorsInvestors
Jan 2020$111.47MSeries C–T. Rowe Price
Feb 2018$100MSeries B–Fidelity Investments
Jan 2018$25MSeries A––
Valuation history

11 investors in total: 11 institutional.

Investors in Generation Bio

Generation Bio has secured backing from 11 investors, including institutional and venture fund investors. Prominent investors backing the company include Fidelity Investments, T. Rowe Price and Farallon Capital Management.

All
Venture Fund
Institutional
InvestorDescriptionFounded YearDomainLocation
Venture capital firm investing in life science and biotechnology sectors
1980atlasventure.comCambridge, United States
Multiple investment strategies are pursued by this hedge fund.
1986faralloncapital.comSan Francisco, United States
Long-term private equity investments in transformational opportunities are pursued.
–invus.comNew York, United States
Investing in Life Sciences sectors like Healthcare and Biotechnology.
–casdincapital.com-
Healthcare ecosystem is supported through investment and innovation by Deerfield.
–deerfield.comNew York, United States
Multi-stage investment firm invests in healthcare and life sciences companies
–foresitecapital.comNew York, United States
Diversified asset management services are provided to investors globally.
1937troweprice.comBaltimore, United States
Diversified investment management services are provided to institutional clients.
–wellington.comBoston, United States
Provider of brokerage accounts, retirement planning, wealth management, and trading platforms
1946fidelity.comBoston, United States
M&A advisory services are provided for healthcare companies.
1995svbsecurities.comBoston, United States
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Investor details for Generation Bio

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People of Generation Bio

16 people are tracked at Generation Bio (3 in leadership, 13 in board & advisors); the tracked headcount is 115.

NameRoleGroup
Phillip Samayoa
Co-FounderLeadership
Mark Angelino
Co-Founder & COOLeadership
Geoff McDonough
CEOLeadership
Gustav Christensen
DirectorBoard & advisors
Charles Rowland
DirectorBoard & advisors
Richard Thompson
AdvisorBoard & advisors
Donald Nicholson
DirectorBoard & advisors
Catherine Stehman-Breen
DirectorBoard & advisors
Adrian Thrasher
AdvisorBoard & advisors
Katherine Fitzgerald
AdvisorBoard & advisors
Kevin Fitzgerald
AdvisorBoard & advisors
Ron Cooper
DirectorBoard & advisors
Jason Rhodes
ChairBoard & advisors
Jeff Jonas
DirectorBoard & advisors
Anthony Quinn
DirectorBoard & advisors
Steven Dowdy
AdvisorBoard & advisors
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IPO & Listings of Generation Bio

Generation Bio is a publicly listed company on the NASDAQ with ticker symbol GBIO in USA, operating in the Health technology sector. As a publicly traded entity, the company provides investors with opportunities to participate in its growth story through equity ownership. The listing enables access to capital markets, enhances corporate visibility, and provides liquidity for shareholders while maintaining transparency through regulatory compliance and regular financial disclosures.

  • IPO date12 Jun 2020
  • Listed onNASDAQ: GBIO
  • Listed entityGeneration Bio Co.
  • Exchange sectorHealth technology
  • ISINUS37148K2096
  • Share price$5.34 (-6.97% on the day) · 2026-02-10
  • Market capitalisation$36.0M
  • EPS (diluted, trailing year)$-9.35
  • Volume (last session)551,924
  • Analyst consensusBuy

Financials of Generation Bio

Exchange-reported annual figures
YearRevenueNet incomeEBITDA
2024$19.9M-$131.7M-$73.4M
2023$5.9M-$126.6M-$126.3M
2022–-$136.6M-$130.9M
2021–-$119.2M-$114.6M
2020–-$80.5M-$77.7M
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Detailed financial statements for Generation Bio

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  • Downloads

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Timeline of Generation Bio

5 dated milestones of Generation Bio across 9 years, from founding to its latest funding, stage changes and deals.

  1. Founded Generation Bio is founded.
  2. Funding First funding round of $25.0M.
  3. Funding Latest funding round, Series C, of $111.5M.
  4. IPO Lists on the stock exchange (IPO).
  5. Exit Acquired by XOMA Corporation.

Competitors of Generation Bio

Generation Bio operates in a dynamic and competitive business environment, facing competition from various established players and emerging companies in the market. The competitive landscape includes prominent companies such as Moderna, BridgeBio, Spark Therapeutics, Alnylam and ATAI, among others.

Company NameDomainFoundedHQ LocationTotal fundingEmployeesDescription
modernatx.com2010Cambridge, United States$2.78B1,312
mRNA-based therapeutics for diseases including cancer and infections are developed.
bridgebio.com2015Palo Alto, United States$434.2M–
Therapeutics for genetic diseases are developed through targeted interventions.
sparktx.com2013Philadelphia, United States$82.8M822
Gene therapies for rare diseases including retinal dystrophies are developed.
alnylam.com2002Cambridge, United States$17M2,100
RNA interference-based therapeutics are developed for multiple disorders.
atai.life2018Munich, Germany$386.67M–
A biopharmaceutical company accelerating innovative mental health treatments.
insitro.com2018San Francisco, United States$643.21M257
An AI-enabled platform is developed for infectious disease treatment.
rhythmtx.com2010Boston, United States$84M115
Developer of peptide therapeutics for the treatment of rare genetic deficiencies
horizontherapeutics.com2008Dublin, Ireland$61.78M–
Developer of drugs for treating rare and autoimmune diseases
ultragenyx.com2010Novato, United States$135.1M837
Therapeutics for rare and ultra-rare metabolic diseases are developed.
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Detailed competitors of Generation Bio

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Web traffic of Generation Bio

The website of Generation Bio (generationbio.com) receives about 4.1K visits a month and ranks #4,660,703 among all websites worldwide, #5,548 in Biotechnology and Pharmaceuticals.

  • Monthly visits
    4.1K

    ▲ 12.5% vs previous month

  • Unique visitors
    1.6K

    per month

  • Global rank
    #4,660,703

    among all websites

  • Category rank
    #5,548

    Health · Biotechnology and Pharmaceuticals

Latest news on Generation Bio

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Complete news archive for Generation Bio

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Similar companies to Generation Bio

10 companies that operate in the same segment as Generation Bio (Genomics & Gene Therapy Platforms), ranked by their profile score on The Company Check.

CompanyDescriptionFoundedLocationTotal fundingRevenueEmployees
mRNA-based therapeutics for diseases including cancer and infections are developed.
2010Cambridge, Massachusetts, United StatesUSD 2.78 BUSD 1.94 B5,800
Digital sequencing technology for cancer detection is developed.
2012Redwood City, California, United StatesUSD 557.5 MUSD 982.02 M2,020
Circulating tumor DNA is screened for early cancer detection.
2016Menlo Park, California, United StatesUSD 3.22 BUSD 147.17 M1,000
Nanopore-based electronic systems for single-molecule analysis are developed.
2005Oxford, Oxfordshire, United KingdomUSD 1.3 BUSD 301.49 M1,480
Provider of genetic test solutions to study ancestry, genealogy, and inherited traits
2006Sunnyvale, California, United StatesUSD 943.53 MUSD 189.9 M265
Provider of DNA testing services to create a family tree and ancestor
2003Yehud, Central District, IsraelUSD 40 M––
Genetically modified cell lines are developed using AAV gene-editing platform.
2007Cambridge, Cambridgeshire, United KingdomUSD 46.29 M––
Gene therapies for rare diseases including retinal dystrophies are developed.
2013Philadelphia, Pennsylvania, United StatesUSD 82.8 MUSD 64.73 M822
Therapeutics for genetic diseases are developed through targeted interventions.
2015Palo Alto, California, United StatesUSD 434.2 MUSD 502.08 M730
Provider of an online genealogy platform offering a host of services
1996Lehi, Utah, United StatesUSD 146.2 M––
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Frequently Asked Questions about Generation Bio

Generation Bio was founded in 2016 and raised its 1st funding round 2 years after it was founded.

Generation Bio is headquartered in Cambridge, United States. It is registered at Cambridge, Massachusetts, United States.

Geoff McDonough is the current CEO of Generation Bio.

Generation Bio is a funded company, having raised a total of $236.47M across 3 funding rounds to date. The company's 1st funding round was a Series A of $25M, raised on Jan 2018.

Generation Bio has 115 employees.

Annual revenue of Generation Bio is $19.89M as on Dec 31, 2024.

Generation Bio was founded in 2016 in Cambridge, United States, within the biotechnology sector. Non-viral gene therapies are provided for conditions such as phenylketonuria, hemophilia A, Wilson disease, Leber congenital amaurosis, and Stargardt disease. The Gene Wave technology enables optimal titration and re-dosing through closed-ended DNA. This ceDNA is packaged in lipid nanoparticles, which dissolve into cell cytoplasm and enter the nucleus to produce proteins.

Generation Bio's top competitors include Moderna, Spark Therapeutics and BridgeBio.

Generation Bio offers ctLNP-siRNA.

Yes, Generation Bio is publicly traded on NASDAQ under the ticker symbol GBIO.

Generation Bio has 11 investors. Key investors include Fidelity Investments, T. Rowe Price, Farallon Capital Management, Atlas Venture, and XOMA Corporation.

Generation Bio operates through Generation Bio Co..

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